The DOI matches its Crossref record.
Might Brushed Nasal Cells Be a Surrogate for CFTR Modulator Clinical Response?
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Patient-derived HNE are precision medicine tools that can predict clinical responsiveness of individuals and likely inform on the theratype of individual mutations or mutation combinations.
“Patient-derived HNE are precision medicine tools that can predict the clinical responsiveness of individuals and likely inform on the theratype of individual mutations or mutation combinations (38–40).”
From Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination (2020) · cites this paper as [39]
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Cites
No references could be resolved yet.
Research works printed but not linked: 5
- O’Sullivan, 2009, Cystic fibrosis, Lancet, 373, 1891, 10.1016/S0140-6736(09)60327-5 · DOI · Paper page
- Accurso, 2014, Sweat chloride as a biomarker of CFTR activity: proof of concept and ivacaftor clinical trial data, J Cyst Fibros, 13, 139, 10.1016/j.jcf.2013.09.007 · DOI
- Wainwright, 2015, Lumacaftor-ivacaftor in patients with cystic fibrosis homozygous for phe508del cftr, N Engl J Med, 373, 1783, 10.1056/NEJMoa1409547 · DOI · Paper page
- Pranke, 2017, Correction of CFTR function in nasal epithelial cells from cystic fibrosis patients predicts improvement of respiratory function by CFTR modulators, Sci Rep, 7, 7375, 10.1038/s41598-017-07504-1 · DOI · Paper page
- Graeber, 2018, Effects of lumacaftor-ivacaftor therapy on cystic fibrosis transmembrane conductance regulator function in Phe508del homozygous patients with cystic fibrosis, Am J Respir Crit Care Med, 197, 1433, 10.1164/rccm.201710-1983OC · DOI
Cited by
Sorted by citations
Veit, G., Roldan, A., Hancock, M. A., Da Fonte, D. F., Xu, H., Hussein, M., Frenkiel, S., Matouk, E., Velkov, T., & Lukacs, G. L. (2020) · JCI Insight · doi:10.1172/jci.insight.139983 · Cited by 250
Metadata
- Authors
- Pranke, I., Hatton, A., Masson, A., Flament, T., Le Bourgeois, M., Chedevergne, F., Bailly, C., Urbach, V., Hinzpeter, A., Edelman, A., & Sermet-Gaudelus, I.
- Affiliations
- Hôpital Necker-Enfants Malades (FR)
- Institut Necker-Enfants Malades, Paris, France
- Hôpital Bretonneau (FR)
- Hôpital Necker-Enfants Malades, Paris, France
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2019-01-01
- Volume
- 199
- Issue
- 1
- Pages
- 123-126
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2896847608
- Cited by
- 50
- References
- 0
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 10 · 2023: 3 · 2022: 11 · 2021: 13 · 2020: 2 · 2019: 5
- FWCI
- 3.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Respiratory and Critical Care Medicine (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Funders
- Vaincre La Mucoviscidose (RC20160501612/1/3/8)
- ABCF Protein Association
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Inhalation and Respiratory Drug Delivery
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- CFTR modulators, cystic fibrosis, clinical response prediction, surrogate markers, airway epithelial cells
- MeSH terms
- Aminopyridines, Cystic Fibrosis, Humans, Nasal Cavity, Nasal Mucosa, Biomarkers, Treatment Outcome, Cystic Fibrosis Transmembrane Conductance Regulator, Benzodioxoles
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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