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Cited by 272Occupational exposure and asthmaAsthma and respiratory diseasesOccupational Health and Safety in Workplaces

The DOI matches its Crossref record; 78 of the 78 references it cites were found in a registry or an index.

An Official American Thoracic Society Statement: Work-Exacerbated Asthma

Henneberger, Paul K., Redlich, Carrie A., Callahan, David B., Harber, Philip, Lemière, Catherine, Martin, James, Tarlo, Susan M., Vandenplas, Olivier, Torén, Kjell·2011·American Journal of Respiratory and Critical Care Medicine
DOI 10.1164/rccm.812011st
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Abstract

RATIONALE: Occupational exposures can contribute to the exacerbation as well as the onset of asthma. However, work-exacerbated asthma (WEA) has received less attention than occupational asthma (OA) that is caused by work. OBJECTIVES: The purpose of this Statement is to summarize current knowledge about the descriptive epidemiology, clinical characteristics, and management and treatment of WEA; propose a case definition for WEA; and discuss needs for prevention and research. METHODS: Information about WEA was identified primarily by systematic searches of the medical literature. Statements about prevention and research needs were reached by consensus. MEASUREMENTS AND MAIN RESULTS: WEA is defined as the worsening of asthma due to conditions at work. WEA is common, with a median prevalence of 21.5% among adults with asthma. Different types of agents or conditions at work may exacerbate asthma. WEA cases with persistent work-related symptoms can have clinical characteristics (level of severity, medication needs) and adverse socioeconomic outcomes (unemployment, reduction in income) similar to those of OA cases. Compared with adults with asthma unrelated to work, WEA cases report more days with symptoms, seek more medical care, and have a lower quality of life. WEA should be considered in any patient with asthma that is getting worse or who has work-related symptoms. Management of WEA should focus on reducing work exposures and optimizing standard medical management, with a change in jobs only if these measures are not successful. CONCLUSIONS: WEA is a common and underrecognized adverse outcome resulting from conditions at work. Additional research is needed to improve the understanding of the risk factors for, and mechanisms and outcomes of, WEA, and to inform and evaluate preventive interventions.

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Crossref · 10.1164/rccm.812011st

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Metadata

Authors
Henneberger, P. K., Redlich, C. A., Callahan, D. B., Harber, P., Lemière, C., Martin, J., Tarlo, S. M., Vandenplas, O., & Torén, K.
ORCID
Venue
American Journal of Respiratory and Critical Care Medicine
Publisher
Oxford University Press (OUP)
Published
2011-08-01
Volume
184
Issue
3
Pages
368-378
ISSN
  • 1073-449X (ISSN-L)
  • 1535-4970
DOI
10.1164/rccm.812011st
OpenAlex
W2142450330
Cited by
272
References
77
Citations by year
2026: 6 · 2025: 12 · 2024: 14 · 2023: 8 · 2022: 16 · 2021: 12 · 2020: 24 · 2019: 27 · 2018: 24 · 2017: 21 · 2016: 16 · 2015: 22 · 2014: 22 · 2013: 28 · 2012: 18
FWCI
3.44
Type
journal article
Language
en
Open access
closed
Licence
academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations
  • American Journal of Respiratory and Critical Care Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B)) (submittedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational exposure and asthma
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational Health and Safety in Workplaces
Keywords
work-exacerbated asthma, occupational asthma, asthma exacerbations, occupational exposure, case definition, prevalence, socioeconomic outcomes, unemployment, quality of life, asthma management, prevention
MeSH terms
Adult, Asthma, Humans, Occupational Diseases, Societies, Medical, United States, Occupational Exposure, Disease Progression

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