Confluent monolayers of cultured human fetal retinal pigment epithelium exhibit morphology and physiology of native tissue

Maminishkis, Arvydas, Chen, Shan, Jalickee, Stephen, Banzon, Tina, Shi, Guangpu, Wang, Fei E., Ehalt, Todd, Hammer, Jeffrey A. +1 more·2006·Investigative Opthalmology & Visual Science

Cited by (401)

Items 101–200 of 401

  1. ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium
    Roxanne H. Croze, David E. Buchholz, Monte J. Radeke, William J. Thi, Qirui Hu, Peter J. Coffey, Dennis Clegg · 2014 · Stem Cells Translational Medicine
  2. Characterization of Barrier Properties and Inducible VEGF Expression of Several Types of Retinal Pigment Epithelium in Medium-Term Culture
    Pete Geisen, J.R. McColm, Bradley King, M. Elizabeth Hartnett · 2006 · Current Eye Research
  3. A New Efficient Protocol for Directed Differentiation of Retinal Pigmented Epithelial Cells from Normal and Retinal Disease Induced Pluripotent Stem Cells
    Azadeh Zahabi, Ebrahim Shahbazi, Hamid Ahmadieh, Seyedeh‐Nafiseh Hassani, Mehdi Totonchi, Adeleh Taei, Najmehsadat Masoudi, Marzieh Ebrahimi, Nasser Aghdami, Ali Seifinejad et al. · 2011 · Stem Cells and Development
  4. Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods
    Lyndsay L. Leach, Roxanne H. Croze, Qirui Hu, Vignesh P. Nadar, Tracy N. Clevenger, Britney O. Pennington, David M. Gamm, Dennis Clegg · 2016 · Journal of Ocular Pharmacology and Therapeutics
  5. A detailed three-step protocol for live imaging of intracellular traffic in polarized primary porcine RPE monolayers
    Toops, Kimberly A., Tan, Li Xuan, Lakkaraju, Aparna · 2014 · Experimental Eye Research
  6. miR‐184 regulates ezrin, <scp>LAMP</scp>‐1 expression, affects phagocytosis in human retinal pigment epithelium and is downregulated in age‐related macular degeneration
    Murad, Najiba, Kokkinaki, Maria, Gunawardena, Nishantha, Gunawan, Mia S., Hathout, Yetrib, Janczura, Karolina J., Theos, Alexander C., Golestaneh, Nady · 2014 · The FEBS Journal
  7. Cultured primary human fetal retinal pigment epithelium (hfRPE) as a model for evaluating RPE metabolism
    Jeffrey Adijanto, Nancy J. Philp · 2014 · Experimental Eye Research
  8. Ion channels and transporters of the retinal pigment epithelium
    Nadine Reichhart, Olaf Strauß · 2014 · Experimental Eye Research
  9. Nanofiber Scaffold-Based Tissue-Engineered Retinal Pigment Epithelium to Treat Degenerative Eye Diseases
    Nathan A. Hotaling, Vladimir Khristov, Qin Wan, Ruchi Sharma, Balendu Shekhar Jha, Mostafa Lotfi, Arvydas Maminishkis, Carl G. Simon, Kapil Bharti · 2016 · Journal of Ocular Pharmacology and Therapeutics
  10. Changes in extracellular matrix cause RPE cells to make basal deposits and activate the alternative complement pathway
    Rosario Fernández‐Godino, Kinga M. Bujakowska, Eric A. Pierce · 2017 · Human Molecular Genetics
  11. A Novel Serum-Free Method for Culturing Human Prenatal Retinal Pigment Epithelial Cells
    David M. Gamm, John Nicholas Melvan, Rebecca L. Shearer, Isabel Pinilla, Grzegorz Sabat, Clive Niels Svendsen, Lynda S. Wright · 2008 · Investigative Ophthalmology & Visual Science
  12. Allogeneic iPSC-Derived RPE Cell Graft Failure Following Transplantation Into the Subretinal Space in Nonhuman Primates
    Trevor J. McGill, Jonathan Stoddard, Lauren M. Renner, Ilhem Messaoudi, Kapil Bharti, Shoukhrat M. Mitalipov, Andreas Katsuya Lauer, David John Wilson, Martha Neuringer · 2018 · Investigative Ophthalmology & Visual Science
  13. Sublytic membrane-attack-complex (MAC) activation alters regulated rather than constitutive vascular endothelial growth factor (VEGF) secretion in retinal pigment epithelium monolayers
    Kunchithapautham, Kannan, Rohrer, Bärbel · 2011 · Journal of Biological Chemistry
  14. Cellular models and therapies for age-related macular degeneration
    David L. Forest, Lincoln V. Johnson, Dennis Clegg · 2015 · Disease Models & Mechanisms
  15. Silencing of the <i>CHM</i> Gene Alters Phagocytic and Secretory Pathways in the Retinal Pigment Epithelium
    Gordiyenko, Nataliya V., Fariss, Robert N., Zhi, Connie, MacDonald, Ian M. · 2010 · Investigative Opthalmology &amp; Visual Science
  16. Minimal Effects of VEGF and Anti-VEGF Drugs on the Permeability or Selectivity of RPE Tight Junctions
    Shaomin Peng, Ron Afshari Adelman, Lawrence J. Rizzolo · 2010 · Investigative Ophthalmology & Visual Science
  17. Chronic oxidative stress upregulates Drusen-related protein expression in adult human RPE stem cell-derived RPE cells: A novel culture model for dry AMD
    David M. Rabin, Richard L. Rabin, Timothy A. Blenkinsop, Sally Temple, Jeffrey H. Stern · 2012 · Aging
  18. Aβ-Induced Senescent Retinal Pigment Epithelial Cells Create a Proinflammatory Microenvironment in AMD
    Lining Cao, Hao Wang, Fang Wang, Ding Xu, Fang Liu, Chaoqi Liu · 2013 · Investigative Ophthalmology & Visual Science
  19. TNF-α disrupts morphologic and functional barrier properties of polarized retinal pigment epithelium
    Makoto Shirasawa, Shozo Sonoda, Hiroto Terasaki, Noboru Arimura, Hiroki Otsuka, Takehiro Yamashita, Eisuke Uchino, Toshio Hisatomi, Tatsuro Ishibashi, Taiji Sakamoto · 2013 · Experimental Eye Research
  20. Metabolomics and Age-Related Macular Degeneration
    Connor N. Brown, B. Green, R. Thompson, A. den Hollander, I. Lengyel · 2018 · Metabolites
  21. Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization
    Hazim, Roni A., Karumbayaram, Saravanan, Jiang, Mei, Dimashkie, Anupama, Lopes, Vanda S., Li, Douran, Burgess, Barry L., Vijayaraj, Preethi, Alva-Ornelas, Jackelyn A., Zack, Jerome A. et al. · 2017 · Stem Cell Research &amp; Therapy
  22. Porous Poly(ε-Caprolactone) Scaffolds for Retinal Pigment Epithelium Transplantation
    Kevin J. McHugh, Sarah L. Tao, Magali Saint‐Geniez · 2014 · Investigative Ophthalmology & Visual Science
  23. Pigment Epithelium-derived Factor Maintains Retinal Pigment Epithelium Function by Inhibiting Vascular Endothelial Growth Factor-R2 Signaling through γ-Secretase
    Zsolt Ablonczy, Annamalai Prakasam, James Fant, Abdul H. Fauq, Craig E. Crosson, Kumar Sambamurti · 2009 · Journal of Biological Chemistry
  24. Electrical signaling in control of ocular cell behaviors
    Min Zhao, Laura Chalmers, Lin Cao, Ana Carolina Vieira, Mark J. Mannis, Brian Reid · 2011 · Progress in Retinal and Eye Research
  25. The contribution of melanoregulin to microtubule-associated protein 1 light chain 3 (LC3) associated phagocytosis in retinal pigment epithelium
    Frost, Laura S., Lopes, Vanda S., Bragin, Alvina, Reyes-Reveles, Juan, Brancato, Jennifer, Cohen, Art, Mitchell, Claire H., Williams, David S., Boesze-Battaglia, Kathleen · 2015 · Molecular Neurobiology
  26. Pluripotent Stem Cells for Retinal Tissue Engineering: Current Status and Future Prospects
    Ratnesh Kumar Singh, Oscar Cuzzani, François Binette, Hal Sternberg, Michael D. West, Igor O. Nasonkin · 2018 · Stem Cell Reviews and Reports
  27. Oxidized Lipoprotein Uptake Through the CD36 Receptor Activates the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells
    Gopalan Gnanaguru, Ariel R. Choi, Dhanesh Amarnani, Patrìcia A. D'Amore · 2016 · Investigative Ophthalmology & Visual Science
  28. Antiapoptotic Properties of α-Crystallin–Derived Peptide Chaperones and Characterization of Their Uptake Transporters in Human RPE Cells
    Parameswaran Gangadharan Sreekumar, Paresh P. Chothe, K. Krishna Sharma, Rinku Baid, Uday B. Kompella, Christine K. Spee, Nandini Kannan, Christina Manh, Stephen J. Ryan, Vadivel Ganapathy et al. · 2013 · Investigative Ophthalmology & Visual Science
  29. Sorsby fundus dystrophy—A review of pathology and disease mechanisms
    Christensen, David R.G., Brown, Ffion E., Cree, Angela J., Ratnayaka, J. Arjuna, Lotery, Andrew J. · 2017 · Experimental Eye Research
  30. Zeb1 Represses Mitf and Regulates Pigment Synthesis, Cell Proliferation, and Epithelial Morphology
    Yongqing Liu, Fei Ye, Qiutang Li, Shigeo Tamiya, Douglas S. Darling, Henry J. Kaplan, Douglas C. Dean · 2009 · Investigative Ophthalmology & Visual Science
  31. PDGF-C and -D Induced Proliferation/Migration of Human RPE Is Abolished by Inflammatory Cytokines
    Rong Li, Arvydas Maminishkis, Fei E. Wang, Sheldon S. Miller · 2007 · Investigative Ophthalmology & Visual Science
  32. C3a triggers formation of sub-retinal pigment epithelium deposits via the ubiquitin proteasome pathway
    Rosario Fernández‐Godino, Eric A. Pierce · 2018 · Scientific Reports
  33. Polarity and epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy
    Hui Zou, Chenli Shan, Linlin Ma, Jia Liu, Ning Yang, Jinsong Zhao · 2020 · PeerJ
  34. Looking into the future: Using induced pluripotent stem cells to build two and three dimensional ocular tissue for cell therapy and disease modeling
    Min Jae Song, Kapil Bharti · 2015 · Brain Research
  35. Interleukin-17A Induces IL-1β Secretion From RPE Cells Via the NLRP3 Inflammasome
    Shujie Zhang, Ning Yu, Rong Zhang, Shenghai Zhang, Jihong Wu · 2016 · Investigative Ophthalmology & Visual Science
  36. Altered mTOR Signaling in Senescent Retinal Pigment Epithelium
    Yan Chen, Jian Wang, Jiyang Cai, Paul Sternberg · 2010 · Investigative Ophthalmology & Visual Science
  37. Ameliorative effect of PACAP and VIP against increased permeability in a model of outer blood retinal barrier dysfunction
    Soraya Scuderi, Agata Grazia D’Amico, Alessandro Castorina, Rosa Imbesi, Maria Luisa Carnazza, Velia D’Agata · 2012 · Peptides
  38. Patient-specific mutations impair BESTROPHIN1’s essential role in mediating Ca2+-dependent Cl- currents in human RPE
    Yao Li, Yu Zhang, Yu Hong Xu, Alec Kittredge, Nancy Ward, Shoudeng Chen, Stephen H. Tsang, Tingting Yang · 2017 · eLife
  39. Matrix Metalloproteinase Activity Creates Pro-Angiogenic Environment in Primary Human Retinal Pigment Epithelial Cells Exposed to Complement
    Mausumi Bandyopadhyay, Bärbel Rohrer · 2012 · Investigative Ophthalmology & Visual Science
  40. Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration
    Kelly Mulfaul, Ema Ozaki, Nilisha Fernando, Kiva Brennan, Kathleen R. Chirco, Emma Connolly, Chris Greene, Arvydas Maminishkis, Robert G. Salomon, Mikhail D. Linetsky et al. · 2020 · Cell Reports
  41. Expression, Localization, and Function of Junctional Adhesion Molecule-C (JAM-C) in Human Retinal Pigment Epithelium
    Matina Economopoulou, Jeffrey A. Hammer, Fei Wang, Robert N. Fariss, Arvydas Maminishkis, Sheldon S. Miller · 2009 · Investigative Ophthalmology & Visual Science
  42. CNTF Mediates Neurotrophic Factor Secretion and Fluid Absorption in Human Retinal Pigment Epithelium
    Rong Li, Rong Wen, Tina M. Banzon, Arvydas Maminishkis, Sheldon S. Miller · 2011 · PLoS ONE
  43. Retinal pigment epithelium (RPE) cytoskeleton in vivo and in vitro
    Vera L. Bonilha · 2013 · Experimental Eye Research
  44. Effects of Proinflammatory Cytokines on the Claudin-19 Rich Tight Junctions of Human Retinal Pigment Epithelium
    Shaomin Peng, Geliang Gan, Veena Rao, Ron Afshari Adelman, Lawrence J. Rizzolo · 2012 · Investigative Ophthalmology & Visual Science
  45. A Multiplex High-Throughput Gene Expression Assay to Simultaneously Detect Disease and Functional Markers in Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium
    Marc Ferrer, Barbara Corneo, Janine A. Davis, Qin Wan, Kiyoharu J. Miyagishima, Rebecca King, Arvydas Maminishkis, Juan Marugán, Ruchi Sharma, Michael S. Shure et al. · 2014 · Stem Cells Translational Medicine
  46. LC–MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line
    Laura Pelkonen, Kazuki Sato, Mika Reinisalo, Heidi Kidron, Masanori Tachikawa, Michitoshi Watanabe, Yasuo Uchida, Arto O. Urtti, Tetsuya Terasaki · 2017 · Molecular Pharmaceutics
  47. Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells
    Luca Tamò, Youssef Hibaoui, Sampada Kallol, Marco P. Alves, Christiane Albrecht, Katrin Hostettler, Anis Féki, Jean‐Sébastien Rougier, Hugues Abriel, Lars Knudsen et al. · 2018 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  48. Ionic Components of Electric Current at Rat Corneal Wounds
    Ana Carolina Vieira, Brian Reid, Lin Cao, Mark J. Mannis, Ivan R. Schwab, Min Zhao · 2011 · PLoS ONE
  49. Investigation and Restoration of BEST1 Activity in Patient-derived RPEs with Dominant Mutations
    Changyi Ji, Yao Li, Alec Kittredge, Austin R. Hopiavuori, Nancy Ward, Peng Yao, Yohta Fukuda, Yu Zhang, Stephen H. Tsang, Tingting Yang · 2019 · Scientific Reports
  50. Docosahexaenoic acid aggravates photooxidative damage in retinal pigment epithelial cells via lipid peroxidation
    Yixiang Liu, Di Zhang, WU Yong-pei, Baoping Ji · 2014 · Journal of Photochemistry and Photobiology B Biology
  51. The Role of RPE Cell-Associated VEGF 189 in Choroidal Endothelial Cell Transmigration across the RPE
    Haibo Wang, Pete Geisen, Erika S. Wittchen, Bradley King, Keith Burridge, Patrìcia A. D'Amore, M. Elizabeth Hartnett · 2010 · Investigative Ophthalmology & Visual Science
  52. Engineering a Blood-Retinal Barrier With Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium: Transcriptome and Functional Analysis
    Shaomin Peng, Geliang Gan, Caihong Qiu, Mei Zhong, Hongyan An, Ron Afshari Adelman, Lawrence J. Rizzolo · 2013 · Stem Cells Translational Medicine
  53. A Bruch's membrane substitute fabricated from silk fibroin supports the function of retinal pigment epithelial cells in vitro
    Audra M. A. Shadforth, Shuko Suzuki, Christina Theodoropoulos, Neil Andrew Richardson, Traian V. Chirilă, Damien G. Harkin · 2015 · Journal of Tissue Engineering and Regenerative Medicine
  54. N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related macular degeneration
    Chia-yi Chen, Esther Melo, Peter Jakob, Arno Friedlein, Brigitta Elsässer, Peter Goettig, Verena Küppers, Frédéric Delobel, Corinne Stucki, Tom P. J. Dunkley et al. · 2018 · Matrix Biology
  55. Expression of inwardly rectifying potassium channel subunits in native human retinal pigment epithelium
    Dongli Yang, Xiaoming Zhang, Bret A. Hughes · 2008 · Experimental Eye Research
  56. RNA‐seq analysis of ageing human retinal pigment epithelium: Unexpected up‐regulation of visual cycle gene transcription
    Joe M. Butler, Wasu Supharattanasitthi, Yit Chiun Yang, Luminita Paraoan · 2021 · Journal of Cellular and Molecular Medicine
  57. Integrin α5β1 Mediates Attachment, Migration, and Proliferation in Human Retinal Pigment Epithelium: Relevance for Proliferative Retinal Disease
    Rong Li, Arvydas Maminishkis, Grit Zahn, Doerte Vossmeyer, Sheldon S. Miller · 2009 · Investigative Ophthalmology & Visual Science
  58. A Multi-Omics Approach Identifies Key Regulatory Pathways Induced by Long-Term Zinc Supplementation in Human Primary Retinal Pigment Epithelium
    Eszter Emri, Elöd Körtvely, Sascha Dammeier, Franziska Klose, David A. C. Simpson, Anneke I. den Hollander, Marius Ueffing, Imre Lengyel · 2020 · Nutrients
  59. IFNγ regulates retinal pigment epithelial fluid transport
    Rong Li, Arvydas Maminishkis, Tina M. Banzon, Qin Wan, Stephen Jalickee, Shan Chen, Sheldon S. Miller · 2009 · American Journal of Physiology-Cell Physiology
  60. Oxidative stress and mitochondrial transfer: A new dimension towards ocular diseases
    Mohana Devi Subramaniam, Mahalaxmi Iyer, Aswathy P. Nair, Dhivya Venkatesan, Sinnakaruppan Mathavan, Nimmisha Eruppakotte, Soumya Kizhakkillach, Manoj kumar Chandran, Ayan Roy, Abilash Valsala Gopalakrishnan et al. · 2020 · Genes & Diseases
  61. Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity
    Marzena Kurzawa‐Akanbi, Nikolaos Tzoumas, Julio C. Corral-Serrano, Rosellina Guarascio, DAVID H. STEEL, Michael E. Cheetham, Lyle Armstrong, Majlinda Lako · 2024 · Progress in Retinal and Eye Research
  62. Pro-angiogenic effect of IFNgamma is dependent on the PI3K/mTOR/translational pathway in human retinal pigmented epithelial cells.
    Baoying Liu, Lisa J. Faia, Mengjun Hu, Robert Burton Nussenblatt · 2010 · PubMed Central
  63. Inflammasomes Induced by 7-Ketocholesterol and Other Stimuli in RPE and in Bone Marrow-Derived Cells Differ Markedly in Their Production of IL-1 and IL-18
    Gongping Shi, S. Chen, Wambui S. Wandu, Osato Ogbeifun, Lindsey F. Nugent, Arvydas Maminishkis, Samuel J. H. Hinshaw, Ignacio R. Rodríguez, Igal Gery · 2015 · Investigative Ophthalmology & Visual Science
  64. Untitled work
    2007 · PubMed
  65. Basal and apical regulation of VEGF-A and placenta growth factor in the RPE/choroid and primary RPE.
    Alexa Klettner, Leyla Kaya, Janina Flach, Jens Flensted Lassen, Felix Treumer, Johann Baptist Roider · 2015 · Europe PMC (PubMed Central)
  66. Cell-autonomous lipid-handling defects in Stargardt iPSC-derived retinal pigment epithelium cells
    Mitra Farnoodian, Devika Bose, Vladimir Khristov, Praveen Joseph Susaimanickam, Savitri Maddileti, Indumathi Mariappan, Mones S. Abu-Asab, Maria Mercedes Campos, Rafael Villasmil, Qin Wan et al. · 2022 · Stem Cell Reports
  67. TRP Channels Localize to Subdomains of the Apical Plasma Membrane in Human Fetal Retinal Pigment Epithelium
    Peter Y. Zhao, Geliang Gan, Shaomin Peng, Shao-Bin Wang, Bo Chen, Ron Afshari Adelman, Lawrence J. Rizzolo · 2015 · Investigative Ophthalmology & Visual Science
  68. Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly
    Najim Lahrouchi, Aman George, Ilham Ratbi, Ronen Schneider, Siham Chafai Elalaoui, Shahida Moosa, Sanita Bharti, Ruchi Sharma, Mones S. Abu-Asab, Felix Onojafe et al. · 2019 · Nature Communications
  69. Cell Biology of the Retinal Pigment Epithelium
    Gabriele Thumann, Stephan Hoffmann, David R. Hinton · 2006 · Elsevier eBooks
  70. Epithelial-Mesenchymal Transition-Like Phenotypic Changes of Retinal Pigment Epithelium Induced by TGF-β Are Prevented by PPAR-γ Agonists
    Hiroki Hatanaka, Noriko Koizumi, Naoki Okumura, EunDuck P. Kay, Eri Mizuhara, Junji Hamuro, Shigeru Kinoshita · 2012 · Investigative Ophthalmology & Visual Science
  71. Role of lysophosphatidic acid in the retinal pigment epithelium and photoreceptors
    Grace E. Lidgerwood, Andrew J. Morris, Alison Conquest, Maciej Daniszewski, Louise A. Rooney, Shiang Yong Lim, Damián Hernández, Helena Hai Liang, Penelope J. Allen, Paul Connell et al. · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  72. In Vitro Epiretinal Membrane Model and Antibody Permeability: Relationship With Anti-VEGF Resistance in Diabetic Macular Edema
    Rina Namba, Hiroki Kaneko, Ayana Suzumura, Hideyuki Shimizu, Keiko Kataoka, Kei Takayama, Kazuhisa Yamada, Yasuhito Funahashi, Seina Ito, Norie Nonobe et al. · 2019 · Investigative Ophthalmology & Visual Science
  73. Reproducible production and image-based quality evaluation of retinal pigment epithelium sheets from human induced pluripotent stem cells
    Ke Ye, Yuto Takemoto, Arisa Ito, Masanari Onda, Nao Morimoto, Michiko Mandai, Masayo Takahashi, Ryuji Kato, Fumitaka Osakada · 2020 · Scientific Reports
  74. Modulation of MCT3 Expression during Wound Healing of the Retinal Pigment Epithelium
    Shannon M. Gallagher‐Colombo, Arvydas Maminishkis, Susan Tate, Gerald B. Grunwald, Nancy J. Philp · 2010 · Investigative Ophthalmology & Visual Science
  75. Retinoid Uptake, Processing, and Secretion in Human iPS-RPE Support the Visual Cycle
    Alberto Muniz, Whitney A. Greene, Mark L. Plamper, Jae Hyek Choi, Anthony J. Johnson, Andrew T. C. Tsin, Heuy-Ching Hetty Wang · 2013 · Investigative Ophthalmology & Visual Science
  76. Longitudinal adaptive optics fluorescence microscopy reveals cellular mosaicism in patients
    HaeWon Jung, Jianfei Liu, Tao Liu, Aman George, Margery G. Smelkinson, Sarah Cohen, Ruchi Sharma, Owen Schwartz, Arvydas Maminishkis, Kapil Bharti et al. · 2019 · JCI Insight
  77. Development of 3D Printed Bruch’s Membrane-Mimetic Substance for the Maturation of Retinal Pigment Epithelial Cells
    Jongmin Kim, Ju Young Park, Jeong Sik Kong, Hyungseok Lee, Jae Yon Won, Dong‐Woo Cho · 2021 · International Journal of Molecular Sciences
  78. Identification of a synergistic interaction between endothelial cells and retinal pigment epithelium
    Carrie Spencer, Stephanie Abend, Kevin J. McHugh, Magali Saint‐Geniez · 2017 · Journal of Cellular and Molecular Medicine
  79. Structure and Function of the Bestrophin family of calcium-activated chloride channels
    Aaron P. Owji, Alec Kittredge, Yu Zhang, Tingting Yang · 2021 · Channels
  80. Development of Retinal Pigment Epithelium from Human Parthenogenetic Embryonic Stem Cells and MicroRNA Signature
    Wenbo Li, Yunshan Zhang, Zhenyu Lu, Lijie Dong, Fei E. Wang, Rong Dong, Xiaorong Li · 2012 · Investigative Ophthalmology & Visual Science
  81. <i>N‐tert‐butyl</i> hydroxylamine, a mitochondrial antioxidant, protects human retinal pigment epithelial cells from iron overload: relevance to macular degeneration
    Voloboueva, Ludmila A., Killilea, David W., Atamna, Hani, Ames, Bruce N. · 2007 · The FASEB Journal
  82. Subcellular Distribution and Activity of Mechanistic Target of Rapamycin in Aged Retinal Pigment Epithelium
    Bo Yu, P. Xu, Zhenyang Zhao, Jiyang Cai, P. Sternberg, Y. Chen · 2014 · Investigative Ophthalmology & Visual Science
  83. Features specific to retinal pigment epithelium cells derived from three-dimensional human embryonic stem cell cultures — a new donor for cell therapy
    Wei Wu, Yuxiao Zeng, Zhengya Li, Qiyou Li, Haiwei Xu, Zheng Qin Yin · 2016 · Oncotarget
  84. Human Retinal Pigment Epithelium Stem Cell (RPESC)
    Janmeet S. Saini, Sally Temple, Jeffrey H. Stern · 2015 · Advances in experimental medicine and biology
  85. Self-Formation of RPE Spheroids Facilitates Enrichment and Expansion of hiPSC-Derived RPE Generated on Retinal Organoid Induction Platform
    Shengxu Liu, Bing Xie, Xiaojing Song, Dandan Zheng, Liwen He, Guilan Li, Guanjie Gao, Fuhua Peng, Minzhong Yu, Jian Ge et al. · 2018 · Investigative Ophthalmology & Visual Science
  86. Cell Therapy for Retinal Dystrophies: From Cell Suspension Formulation to Complex Retinal Tissue Bioengineering
    Karim Ben M’Barek, Christelle Monville · 2019 · Stem Cells International
  87. Secretory proteostasis of the retinal pigmented epithelium: Impairment links to age-related macular degeneration
    Luminita Paraoan, Umar Sharif, Emil Carlsson, Wasu Supharattanasitthi, Nur Musfirah Mahmud, Tengku Ain Kamalden, Paul Stephenson Hiscott, Malcolm Joseph Jackson, Ian Grierson · 2020 · Progress in Retinal and Eye Research
  88. Highly Differentiated Human Fetal RPE Cultures Are Resistant to the Accumulation and Toxicity of Lipofuscin-Like Material
    Qitao Zhang, Feriel Presswalla, Melissa A. Calton, Carol J. Charniga, Jeffrey H. Stern, Sally Temple, Douglas Vollrath, David N. Zacks, Robin R. Ali, Debra A. Thompson et al. · 2019 · Investigative Ophthalmology & Visual Science
  89. Pigment Epithelium-Derived Factor as a Possible Treatment Agent for Choroidal Neovascularization
    Lei Xi · 2020 · Oxidative Medicine and Cellular Longevity
  90. Characterization and pharmacologic targeting of EZH2, a fetal retinal protein and epigenetic regulator, in human retinoblastoma
    Mehnaz Khan, Laura L. Walters, Qiang Li, Dafydd G. Thomas, Jason M. L. Miller, Qitao Zhang, Andrew P. Sciallis, Yu Liu, Brian J. Dlouhy, Patrice Elie Fort et al. · 2015 · Laboratory Investigation
  91. Experimental Models for Study of Retinal Pigment Epithelial Physiology and Pathophysiology
    Arvydas Maminishkis, Sheldon S. Miller · 2010 · Journal of Visualized Experiments
  92. Defined Medium Conditions for the Induction and Expansion of Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium
    Grace E. Lidgerwood, Shiang Yong Lim, Duncan E. Crombie, Ray Ali, Katherine P. Gill, Damián Hernández, Joshua Kie, Alison Conquest, Hayley S. Waugh, Raymond C.B. Wong et al. · 2015 · Stem Cell Reviews and Reports
  93. Directional ABCA1-mediated cholesterol efflux and apoB-lipoprotein secretion in the retinal pigment epithelium
    Nicholas N. Lyssenko, Naqi Haider, Antonino Picataggi, Eleonora Cipollari, Wanzhen Jiao, Michael C. Phillips, Daniel James Rader, Venkata Ramana Murthy Chavali · 2018 · Journal of Lipid Research
  94. Disease-associated mutations of claudin-19 disrupt retinal neurogenesis and visual function
    Shao-Bin Wang, Tao Xu, Shaomin Peng, Deepti Singh, Maryam Ghiassi-Nejad, Ron Afshari Adelman, Lawrence J. Rizzolo · 2019 · Communications Biology
  95. Retinal pigment epithelium cells produce VEGF in response to oxidized phospholipids through mechanisms involving ATF4 and protein kinase CK2
    Andreas Pollreisz, Taras Afonyushkin, Olga Oskolkova, Флориан Грубер, Valery N. Bochkov, Ursula Margarethe Schmidt-Erfurth · 2013 · Experimental Eye Research
  96. Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration
    Yi-Ting Tsai, Yao Li, Joseph Ryu, Pei-Yin Su, Chia-Hua Cheng, Wen-Hsuan Wu, Yong-Shi Li, Peter M. J. Quinn, Kam W. Leong, Stephen H. Tsang · 2021 · The American Journal of Human Genetics
  97. Genetic analyses of human fetal retinal pigment epithelium gene expression suggest ocular disease mechanisms
    Boxiang Liu, Melissa A. Calton, Nathan S. Abell, Gillie Benchorin, Michael J. Gloudemans, Ming Chen, Jane G. Hu, Xin Li, Brunilda Balliu, Dean Bok et al. · 2019 · Communications Biology
  98. Compromised phagosome maturation underlies RPE pathology in cell culture and whole animal models of Smith-Lemli-Opitz Syndrome
    Ramachandra Rao, Sriganesh, Pfeffer, Bruce A., Más Gómez, Néstor, Skelton, Lara A., Keiko, Ueda, Sparrow, Janet R., Rowsam, Aryn M., Mitchell, Claire H., Fliesler, Steven J. · 2018 · Autophagy
  99. The Construction of Retinal Pigment Epithelium Sheets with Enhanced Characteristics and Cilium Assembly Using iPS Conditioned Medium and Small Incision Lenticule Extraction Derived Lenticules
    Jianing Gu, Yini Wang, Zekai Cui, Hong Li, Shenyang Li, Xu Yang, Xin Yan, Chengcheng Ding, Shibo Tang, Jiansu Chen · 2019 · Acta Biomaterialia
  100. Membrane Attack Complex Mediates Retinal Pigment Epithelium Cell Death in Stargardt Macular Degeneration
    Eunice Sze Yin Ng, Nermin Kady, Jane G. Hu, Arpita R. Dave, Zhichun Jiang, Jacqueline Pei, Michael B. Gorin, Anna Matynia, Roxana A. Radu · 2022 · Cells