Accelerated Accumulation of Lipofuscin Pigments in the RPE of a Mouse Model for ABCA4-Mediated Retinal Dystrophies following Vitamin A Supplementation

Radu, Roxana A., Yuan, Quan, Hu, Jane, Peng, Jennifer H., Lloyd, Marcia, Nusinowitz, Steven, Bok, Dean, Travis, Gabriel H.·2008·Investigative Opthalmology & Visual Science

Cited by (188)

Items 101–188 of 188

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  12. Impaired cathepsin D in retinal pigment epithelium cells mediates Stargardt disease pathogenesis
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  15. Test-Retest Reliability and Inter-Ocular Symmetry of Multi-Focal Electroretinography in Stargardt Disease
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  18. Systemic complement activation levels in Stargardt disease
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  20. Excessive retinol intake exacerbates choroidal neovascularization through upregulated vascular endothelial growth factor in retinal pigment epithelium in mice
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  21. Clinical Utility Gene Card for: autosomal recessive cone-rod dystrophy
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  22. Late-onset Stargardt disease
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  23. The Ophthalmic Experience: Unanticipated Primary Findings in the Era of Next Generation Sequencing
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  24. Absence of Genotype/Phenotype Correlations Requires Molecular Diagnostic to Ascertain Stargardt and Stargardt-Like Swiss Patients
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  30. Bisretinoids as a Source of Early Photoreceptor Pathology in Stargardt Disease
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  32. Macular degeneration: A possible biochemical mechanism
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  33. Identification of genetic variation and haplotype structure of the canine ABCA4 gene for retinal disease association studies
    Barbara Zangerl, S. J. Lindauer, Gregory M. Acland, Geoffrey K. Aguirre · 2010 · Molecular Genetics and Genomics
  34. Interlinks Between Vitamin A and Retinopathy
    Rahul K. Reddy, Marc Comaratta · 2019 · Elsevier eBooks
  35. Rescue of the Stargardt Disease Phenotype in Abca4 Knockout Mice Through Dietary Modulation of the Vitamin A Receptor RBPR2
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  37. Fenretinide-Associated Multilayered Retinal Hemorrhage in a Patient with Hairy Cell Leukemia
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  38. Ophthalmic Opportunities For The Medicinal Chemist
    PF Kador · 2012 · Future Medicinal Chemistry
  39. Primary Photoreceptor Degenerations: Retinitis Pigmentosa
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  40. Pharmakotherapie von ABCA4-assoziierten Netzhautdystrophien
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  41. Decoding pediatric inherited retinal dystrophies: Bridging genetic complexity and clinical heterogeneity
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  42. Loss of retinal stem cell reserve and lipofuscin accumulation accelerates cone-rod degeneration and replicates Stargardt disease in abca4b null zebrafish
    Divya Pidishetty, Santhosh Kumar Damera, Murali Murugavel, Praveen Joseph Susaimanickam, Sai Naga Sri Harsha Chittajallu, Gopal Kushawah, Puja Sarkar, Shrikant R. Bharadwaj, Rakesh K. Mishra, Indumathi Mariappan · 2025 · Scientific Reports
  43. Stargardt disease: progress, enigmas, and prospects for therapeutic intervention
    Victoria A. C. Palmgren, Mustansir Pindwarawala, Ali Hosseinzadeh, Robert S. Molday · 2026 · Expert Review of Ophthalmology
  44. Uncovering mitochondrial defects in photoreceptors opens therapeutic opportunities for Stargardt disease
    Simona Brillante, Mariagrazia Volpe, Anna Diana, Santiago Negueruela, Marta Molinari, Rosa Saurino, Eva Cipollaro, Elena Polishchuk, Erika Tenderini, Carla Damiano et al. · 2026 · Proceedings of the National Academy of Sciences
  45. Morbus Stargardt: Genetik, molekulare Mechanismen, mögliche Lebensstilinterventionen und Pharmakotherapie
    Theresa Lipsky, Sophia Dithmar, Georg Ansari, Virginie Peter, Hanno J. Bolz, Tobias Duncker, Monika Fleckenstein, Peter Charbel Issa, Christina Gerth‐Kahlert, Moreno Menghini et al. · 2026 · Die Ophthalmologie
  46. Two distinct phenotypes in pigmented cells of different embryonic origins in eyes of pale ear mice
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  47. The value of genetic testing for inherited retinal disease caused by mutations in the ABCA4 gene in South Africans
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  48. Gene Therapy, Diet and Drug Approaches to Treating Inherited Retinal Disease
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  49. Retinal repair in tissue engineering perspectives
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  50. Zelltherapie am Augenhintergrund – gestern, heute, morgen
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  51. Genetic Etiology and Clinical Consequences of Cone Disorders
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  52. Recherche de gènes impliqués dans des rétinopathies canines comme modèles de rétinites pigmentaires humaines
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  53. Characterization of RPE65 and RDH12, two enzymes associated with retinal dystrophy and retinoid processing
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  60. Thematic Review Series: Lipids and Lipid Metabolism in the Eye Phospholipid meets all- trans -retinal: the making of RPE bisretinoids
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  61. LETTER TO THE EDITOR: RETINOIC ACID RECEPTOR BETA IN PATHOPHYSIOLOGY OF AGE-RELATED MACULAR DEGENERATION
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  62. called 'Quick 7' (which provides a genetic diagnosis, i.e. identification of both mutations, in 40% of Afrikaner patients with STGD
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  63. Macular disease genetics and supplementation: the evidence for choosing wisely
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  65. Animal and Human Models of Retinal Diseases
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  78. Dysregulated DNA Methylation in Abca4-/- Retinal Pigment Epithelium: Insights into Early Stage of Stargardt Disease
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  84. Abca4 Knockdown in the Cone-Rich Rodent Psammomys Obesus Leads to Stargardt's Disease-Like Progressive Retinal Degeneration
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  88. DGAT1-associated lipid-retinoid dysregulation correlates with metabolic impairment in the RPE of Stargardt disease
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