Effects of p38 MAPK Inhibition on Early Stages of Diabetic Retinopathy and Sensory Nerve Function

Du, Yunpeng, Tang, Jie, Li, Guanyuan, Berti-Mattera, Liliana, Lee, Chieh Allen, Bartkowski, Darian, Gale, David, Monahan, Joe +3 more·2010·Investigative Opthalmology & Visual Science
DOI 10.1167/iovs.09-3674

Cited by (136)

Items 101–136 of 136

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  4. Atypical p38 Kinase Signaling in Retinal Vascular Damage and Recovery
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  5. MAPK8 and HDAC6: potential biomarkers related to autophagy in diabetic retinopathy based on bioinformatics analysis
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  6. β-elemene down-regulates HIF-lα, VEGF and iNOS in human retinal pigment epithelial cells under high glucose conditions
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  7. Insight into dysregulated VEGF-related genes in diabetic retinopathy through bioinformatic analyses
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  8. Khellin a promising natural compound for alleviation of diabetic nephropathy: Evidence from in-silico, in-vitro and in-vivo studies
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  9. The impact of p38 MAPK, 5-HT/DA/E signaling pathways in the development and progression of cardiovascular diseases and heart failure in type 1 diabetes
    Ramugounder Ramakrishnan · 2020 · AIMS molecular science
  10. Biomarker potential of vitreous microRNA in retinal disease: a meta-analysis
    Diana Joseph, Brian Grover, Michael Telias · 2024 · medRxiv
  11. Systematic review on biomarker potential of vitreous microRNA in retinal disease
    Diana Joseph, Brian Grover, Michael Telias · 2025 · Frontiers in Ophthalmology
  12. MicroRNA-183 Repression Ameliorates Mitochondrial Dysregulation and Retinal Degeneration in Mice via P38-MAPK/NF-κB Signaling: Implications for Diabetic Retinopathy
    Yunzhi Lin, Wei Zhao, Ji-Ping Cai, Qian Shi, Jing Lin · 2023 · International Journal of Pharmacology
  13. The Multifaceted Roles of LncRNAs in Diabetic Complications: A Promising Yet Perplexing Paradigm
    Saumik Biswas, Subrata Chakrabarti · 2020 · RNA technologies
  14. Effectiveness of Hydroalcoholic Seed Extract of Securigera securidaca on Pancreatic Local Renin-Angiotensin System and Its Alternative Pathway in Streptozotocin-Induced Diabetic Animal Model
    Fatemeh Khomari, Bahar Kiani, Shahin Alizadeh‐Fanalou, Mohammad Babaei, Ali Kalantari‐Hesari, Iraj Alipourfard, Fatemeh Mirzaei, Sahar Yarahmadi, Elham Bahreini · 2023 · Oxidative Medicine and Cellular Longevity
  15. Pathogenesis of diabetic microvascular complications
    Josephine Maree Forbes, Brooke E. Harcourt · 2015
  16. Exploring lncRNAs associated with human pancreatic islet cell death induced by transfer of adoptive lymphocytes in a humanized mouse model
    M.M. Hossain, Regan Roat, J. Christopherson, Colette Free, Ansarullah, Brian P. James, Zhiguang Guo · 2023 · Frontiers in Endocrinology
  17. Anthrax lethal toxin suppresses high glucose induced VEGF over secretion through a post-translational mechanism.
    Weiwei Zhang, Xin Wang, Ping Xie, Songtao Yuan, Qinghuai Liu · 2015 · PubMed Central
  18. Retraction
    2019 · BioFactors · Retracted
  19. Capillary Degeneration in Diabetic Retinopathy
    Timothy S. Kern · 2011 · Springer eBooks
  20. Effects and tissue penetration of anti-inflammatory drugs and peptides in an ex vivo fetal membrane perfusion model
    Lisa Faye Stinson · 2013 · UWA Profiles and Research Repository (UWA)
  21. Regenerative Therapies for Retinopathy
    Ramesh Periasamy, Rajashekhar Gangaraju · 2016 · Springer eBooks
  22. Efeitos da terapia laser de baixa intensidade (LLLT) em modelo de neuropatia diabética experimental
    Willians Fernando Vieira · 2020
  23. Anti-hyperalgesic effects of photobiomodulation therapy (904 nm) on streptozotocin-induced diabetic neuropathy: A role for MAPK pathway and calcium dynamics
    Willians Fernando Vieira, Kauê Franco Malange, Silviane Fernandes de Magalhães, Júlia Borges Paes Lemes, Gilson Gonçalves dos Santos, Catarine Massucato Nishijima, Alexandre Leite Rodrigues de Oliveira, Maria Alice da Cruz‐Höfling, Carlos Amílcar Parada, Cláudia Herrera Tambeli · 2022 · Research Square
  24. Peripheral Neuropathy: A review of mechanism-based treatments with a focus on metformin as a possible choice
    Omid Arasteh · 2023 · Journal of Clinical Images and Medical Case Reports
  25. Peripheral Neuropathy: A review of mechanism-based treatments with a focus on metformin as a possible choice
    Omid Arasteh · 2023 · Journal of Clinical Images and Medical Case Reports
  26. Mechanical regulation of retinal vascular inflammation and degenerationin diabetes
    Sathishkumar Chandrakumar, Irene Santiago Tierno, Mahesh Agarwal, Emma M. Lessieur, Yunpeng Du, Jie Tang, Jianying Z. Kiser, Xiao Yang, Anthony Rodriguez, Timothy S. Kern et al. · 2023
  27. Mechanical regulation of retinal vascular inflammation and degenerationin diabetes
    Sathishkumar Chandrakumar, Irene Santiago Tierno, Mahesh Agarwal, Emma M. Lessieur, Yunpeng Du, Jie Tang, Jianying Z. Kiser, Xiao Yang, Anthony Rodriguez, Timothy S. Kern et al. · 2023
  28. Effect of cellular protein kinase blockade on neurofilament expression in the retina during experimental diabetic retinopathy
    K.O. Usenko · 2025 · Archive of Ukrainian Ophthalmology
  29. Additional file 1 of 4D label-free proteomics analysis of oxygen-induced retinopathy with or without anti-VEGF treatment
    Xu, Zhaokai, Yubo Wu, Mao, Jianbo, Yiqi Chen, Huan Chen, ShiAn Zhang, Jiafeng Yu, Deng, Xinyi, Shen, Lijun · 2024 · Figshare
  30. STING deficiency alleviates scar formation after glaucoma filtration surgery by suppressing p38 MAPK-induced inflammation in mice
    Huifang Ye, Xinlei Lu, Hongjin Chen, Xi Yang, Han Xu, Lei Huang, Qinxiang Zheng, R. Le, Yuanbo Liang · 2026 · Eye and Vision
  31. Theophylline Inhibits Capillary Degeneration in Early Diabetic Retinopathy
    Emma M. Lessieur, Aicha Saadane, Yunpeng Du, Jianying Z. Kiser, Alice Oum, Zak R. Bollinger, Chieh A. Lee, Jie Tang, Timothy S. Kern · 2026 · Investigative Ophthalmology & Visual Science
  32. Microglial activation in diabetic neuropathic pain: Molecular trigger mechanisms, neuroimmune crosstalk, and emerging therapeutic targets
    Jilin Wang, Huamao Zhou · 2026 · Neuropeptides
  33. Decoding the ceRNA network in diabetic retinopathy: Identification of MEG3 as a hub lncRNA and therapeutic target
    Shashank Rao Padubidri, Sreelakshmi K V, Budheswar Dehury · 2026 · Gene Reports
  34. Hydroxysafflor Yellow A for Diabetic Retinopathy: A Critical Review of Retinal Neurovascular Mechanisms and Systemic-to-Ocular Pharmacokinetic Barriers
    Jiaqi Liu, Wenjing Liu, Lu Li, Qianqian Zhang, Jun Zhang, Wenjie Yan · 2026 · Antioxidants
  35. Diabetic retinopathy: shaped by the “hidden hand” of post-translational modifications
    Ruihan Xiao, M Zhang · 2026 · Molecular Neurodegeneration
  36. Atypical p38 kinase signaling and pathological impact on human health
    Fredejah T. Royer, Lillian Schulz, Abby Young, Johnathan Burns, Emmanuel Owusu, Yash Jadhav, Kelly Hanner, Neil Justin Grimsey · 2026 · Biochemical Journal