CoChat
Sign Up
Cited by 53

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Pathogenic Role of the Wnt Signaling Pathway Activation In Laser-Induced Choroidal Neovascularization

Hu, Yang, Chen, Ying, Lin, Mingkai, Lee, Kyungwon, Mott, Robert A., Ma, Jian-xing·2013·Investigative Opthalmology & Visual Science
DOI 10.1167/iovs.12-10281
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1167/iovs.12-10281

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 37

  1. Munoz B, Klein R, Rodriguez J, Snyder R, West SK. Prevalence of age-related macular degeneration in a population-based sample of Hispanic people in Arizona: Proyecto VER. Arch Ophthalmol. 2005;123:1575-1580.
  2. Orsulic S, Peifer M. Cell-cell signalling: wingless lands at last. Curr Biol. 1996;6:1363-1367.
  3. Tamai K, Zeng X, Liu C, et al. A mechanism for Wnt coreceptor activation. Mol Cell. 2004;13:149-156.
  4. Bilic J, Huang YL, Davidson G, et al. Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation. Science. 2007;316:1619-1622.
  5. Liu G, Bafico A, Harris VK, Aaronson SA. A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor. Mol Cell Biol. 2003;23:5825-5835.
  6. Piao S, Lee SH, Kim H, et al. Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta- catenin signaling. PLoS One. 2008;3:e4046.
  7. Wu G, Huang H, Garcia Abreu J, He X. Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6. PLoS One. 2009;4:e4926.
  8. Beagle B, Johnson GV. Differential modulation of TCF/LEF-1 activity by the soluble LRP6-ICD. PLoS One. 2010;5:e11821.
  9. Ojesina AI. The role of beta-catenin in regulating angiogenesis in Wilms tumor. J Pediatr Surg. 2004;39:1446-1447; author reply 1447.
  10. Tachikawa K, Schroder O, Frey G, Briggs SP, Sera T. Regulation of the endogenous VEGF-A gene by exogenous designed regulatory proteins. Proc Natl Acad Sci U S A. 2004;101: 15225-15230.
  11. Easwaran V, Lee SH, Inge L, et al. beta-Catenin regulates vascular endothelial growth factor expression in colon cancer. Cancer Res. 2003;63:3145-3153.
  12. Lichtlen PD, Lam T, Nork M, Streit T, Urech DM. Relative contribution of VEGF and TNF-alpha in the cynomolgus laser- induced CNV model: comparing efficacy of bevacizumab, adalimumab and ESBA105. Invest Ophthalmol Vis Sci. 2010; 51:4738-4745.
  13. Lu M, Adamis AP. Molecular biology of choroidal neovascular- ization. Ophthalmol Clin North Am. 2006;19:323-334.
  14. Miller H, Miller B, Ishibashi T, Ryan SJ. Pathogenesis of laser- induced choroidal subretinal neovascularization. Invest Oph- thalmol Vis Sci. 1990;31:899-908.
  15. Toma HS, Barnett JM, Penn JS, Kim SJ. Improved assessment of laser-induced choroidal neovascularization. Microvasc Res. 2010;80:295-302.
  16. Sheets KG, Zhou Y, Ertel MK, et al. Neuroprotectin D1 attenuates laser-induced choroidal neovascularization in mouse. Mol Vis. 2010;16:320-329.
  17. Takehana Y, Kurokawa T, Kitamura T, et al. Suppression of laser-induced choroidal neovascularization by oral tranilast in the rat. Invest Ophthalmol Vis Sci. 1999;40:459-466.
  18. Chen Y, Hu Y, Lu K, Flannery JG, Ma JX. Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization. J Biol Chem. 2007; 282:34420-34428.
  19. Zhou T, He X, Cheng R, et al. Implication of dysregulation of the canonical wingless-type MMTV integration site (WNT) pathway in diabetic nephropathy. Diabetologia. 2012;55:255- 266.
  20. Chen Y, Hu Y, Moiseyev G, Zhou KK, Chen D, Ma JX. Photoreceptor degeneration and retinal inflammation induced by very low-density lipoprotein receptor deficiency. Micro- vasc Res. 2009;78:119-127.
  21. Zhou T, Hu Y, Chen Y, et al. The pathogenic role of the canonical Wnt pathway in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2010;51:4371-4379.
  22. Zhou T, Zhou KK, Lee K, et al. The role of lipid peroxidation products and oxidative stress in activation of the canonical wingless-type MMTV integration site (WNT) pathway in a rat model of diabetic retinopathy. Diabetologia. 2011;54:459- 468.
  23. Zhang XZ, Jiang JB, Luo XQ, et al. Effect of vascular endothelial growth factor small interfering RNA (siRNA) on retinal microvascular endothelial cells under hypoxia condition in vitro [in Chinese]. Zhonghua Er Ke Za Zhi. 2009;47:457-461.
  24. Falkenstein IA, Cheng L, Wong-Staal F, et al. Toxicity and intraocular properties of a novel long-acting anti-proliferative and anti-angiogenic compound IMS2186. Curr Eye Res. 2008; 33:599-609.
  25. Muther PS, Semkova I, Schmidt K, et al. Conditions of retinal glial and inflammatory cell activation after irradiation in a GFP- chimeric mouse model. Invest Ophthalmol Vis Sci. 2010;51: 4831-4839.
  26. Tsubota K. Oxidative stress and inflammation: hypothesis for the mechanism of aging [in Japanese]. Nihon Ganka Gakkai Zasshi. 2007;111:193-205; discussion 206.
  27. Zhuang P, Shen Y, Lin BQ, Zhang WY, Chiou GC. Effect of quercetin on formation of choroidal neovascularization (CNV) in age-related macular degeneration(AMD). Yan Ke Xue Bao. 2011;26:23-29.
  28. Shi X, Semkova I, Muther PS, Dell S, Kociok N, Joussen AM. Inhibition of TNF-alpha reduces laser-induced choroidal neovascularization. Exp Eye Res. 2006;83:1325-1334.
  29. Chen Y, Hu Y, Zhou T, et al. Activation of the Wnt pathway plays a pathogenic role in diabetic retinopathy in humans and animal models. Am J Pathol. 2009;175:2676-2685.
  30. Jasielska M, Semkova I, Shi X, et al. Differential role of tumor necrosis factor (TNF)-{alpha} receptors in the development of choroidal neovascularization. Invest Ophthalmol Vis Sci. 2010;51:3874-3883.
  31. Mi K, Johnson GV. Role of the intracellular domains of LRP5 and LRP6 in activating the Wnt canonical pathway. J Cell Biochem. 2005;95:328-338.
  32. Gong Y, Bourhis E, Chiu C, et al. Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies. PLoS One. 2010;5:e12682.
  33. Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature. 1998;391: 357-362.
  34. Sakane H, Yamamoto H, Kikuchi A. LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse. J Cell Sci. 2010;123:360-368.
  35. Ettenberg SA, Charlat O, Daley MP, et al. Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibod- ies. Proc Natl Acad Sci U S A. 2010;107:15473-15478.
  36. Lee K, Hu Y, Ding L, et al. Therapeutic potential of a monoclonal antibody blocking the wnt pathway in diabetic retinopathy. Diabetes. 2012;61:2948-2957.
  37. Berger C, Madshus IH, Stang E. Cetuximab in combination with anti-human IgG antibodies efficiently down-regulates the EGF receptor by macropinocytosis. Exp Cell Res. 2012;318: 2578-2591.

Cited by

Sorted by citations

Metadata

Authors
Hu, Y., Chen, Y., Lin, M., Lee, K., Mott, R. A., & Ma, J.-X.
Affiliations
  • From the Department of Physiology and Harold Hamm Diabetes Center, University of Oklahoma, Health Sciences Center, Oklahoma City, Oklahoma. 2These authors contributed equally to the work presented here and should therefore be regarded as equivalent author
  • From the Department of Physiology and Harold Hamm Diabetes Center, University of Oklahoma, Health Sciences Center, Oklahoma City, Oklahoma.
Venue
Investigative Opthalmology & Visual Science
Publisher
Association for Research in Vision and Ophthalmology (ARVO)
Published
2013-01-07
Volume
54
Issue
1
Pages
141
ISSN
1552-5783
DOI
10.1167/iovs.12-10281
Cited by
53
References
2
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review