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Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1
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MethodsMice.Dgat1 -/-mice (∼95% C57BL/6 and 5% 129/SvJae background) were generated previously (4).Wild-type (Dgat1 +/+ ), ob/+, and A Y /a mice (all in C57BL/6 background) were from the The Jackson Laboratory (Bar Harbor, Maine, USA).A Y /a mice are obese and insulin resistant, reflecting the antagonism of melanocyte-
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Metadata
- Authors
- Chen, H. C., Smith, S. J., Ladha, Z., Jensen, D. R., Ferreira, L. D., Pulawa, L. K., McGuire, J. G., Pitas, R. E., Eckel, R. H., & Farese, R. V.
- Venue
- Journal of Clinical Investigation
- Published
- 2002-04-15
- Volume
- 109
- Issue
- 8
- Pages
- 1049-1055
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W4244906287
- Cited by
- 266
- References
- 0
- FWCI
- 6.81
- Type
- journal article
- Language
- en
- Open access
- bronze
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