The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
An Adaptation of the Nitrous Oxide Method to the Study of the Cerebral Circulation in Children; Normal Values for Cerebral Blood Flow and Cerebral Metabolic Rate in Childhood1
Open accessAbstract
Determined by the method of estisting the significance of the difference between two means.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“the relative energy and oxygen demands of the developing brain are markedly greater than that of the adult brain (Kennedy and Sokoloff, 1957).”
From The Cellular and Molecular Landscapes of the Developing Human Central Nervous System (2016) · cites this paper as Kennedy and Sokoloff, 1957
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Kety, S. S., & Schmidt, C. F. (1948) · Journal of Clinical Investigation · doi:10.1172/jci101994 · Cited by 2,058
Slyke, D. D. V., & Neill, J. M. (1924) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)85145-6 · Cited by 2,007
Kety, S. S., & Schmidt, C. F. (1948) · Journal of Clinical Investigation · doi:10.1172/jci101995 · Cited by 1,827 · cited 2×
“despite a slight increase in cerebral blood flow (8), the latter change probably a secondary effect of respiratory depression and consequent elevation of blood carbon dioxide tension (9).”
BackgroundQuantitative Clinical Chemistry
Peters, J. P., & Slyke, D. D. V. (1932) · American Journal of Clinical Pathology · doi:10.1093/ajcp/2.6.492 · Cited by 1,580
Drabkin, D. L., & Austin, J. H. (1935) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)74965-x · Cited by 1,018
Quantitative Clinical Chemistry.
(1932) · Archives of Internal Medicine · doi:10.1001/archinte.1932.00150140175014 · Cited by 838
THE EFFECT OF TEMPERATURE ON THE pH OF BLOOD AND PLASMA IN VITRO
Rosenthal, T. B. (1948) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)35552-2 · Cited by 587
Scheinberg, P., & Stead, E. A. (1949) · Journal of Clinical Investigation · doi:10.1172/jci102150 · Cited by 363
Slyke, D. D. V. (1925) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)84758-5 · Cited by 326
Circulation and metabolism of the human brain in health and disease
Kety, S. S. (1950) · The American Journal of Medicine · doi:10.1016/0002-9343(50)90363-9 · Cited by 281
Research works printed but not linked: 6
- Stroud, M. W., Lambertsen, C. J., Wendel, H., and Daley, M. deB., Comparison of continuous and intermittent sampling in nitrous oxide method for determining cerebral blood flow. Federation Proc., 1954, 13, 147.
- Kennedy, C., A micro method for the determination of nitrous oxide in blood. J. Applied Physiol., In press.
- Gibbs, E. L., Lennox, W. G., and Gibbs, F. A., Bi- lateral internal jugular blood. Comparison of A-V differences, oxygen-dextrose ratios and re- spiratory quotients. Am. J. Psychiat., 1945, 102, 184.
- Kety, S. S., Changes in cerebral circulation and oxy- gen consumption which accompany maturation and aging in International Neurochemical Symposium, 1st, Magdalen College, Oxford, 1954, Biochem- istry of the Developing Nervous System. New York, Academic Press, 1955, p. 208.
- Schmidt, C. F., and Hendrix, J. P., The action of chemical substances on cerebral blood-vessels. A. Research Nerv. & Ment. Dis., Proc., 1937, 18, 229.
- White House Conference on Child Health and Pro- tection. Sect I. Medical Service Committee on Growth and Development. Growth and Develop- ment of the Child. Part II. Anatomy and Physi- ology. New York, Century Press, 1933, p. 180.
Cited by
Sorted by citations
Positron emission tomography study of human brain functional development
Chugani, H. T., Phelps, M. E., & Mazziotta, J. C. (1987) · Annals of Neurology · doi:10.1002/ana.410220408 · Cited by 1,548
Brain Glucose Metabolism: Integration of Energetics with Function
Dienel, G. A. (2018) · Physiological Reviews · doi:10.1152/physrev.00062.2017 · Cited by 911
The Cellular and Molecular Landscapes of the Developing Human Central Nervous System
Silbereis, J. C., Pochareddy, S., Zhu, Y., Li, M., & Sestan, N. (2016) · Neuron · doi:10.1016/j.neuron.2015.12.008 · Cited by 818
Klingberg, T., Forssberg, H., & Westerberg, H. (2002) · Journal of Cognitive Neuroscience · doi:10.1162/089892902317205276 · Cited by 695
Chugani, H. T., & Phelps, M. E. (1986) · Science · doi:10.1126/science.3945811 · Cited by 663
Metadata
- Authors
- Kennedy, C., & Sokoloff, L.
- Affiliations
- Children's Hospital of Philadelphia (US)
- Venue
- Journal of Clinical Investigation
- Published
- 1957-07-01
- Volume
- 36
- Issue
- 7
- Pages
- 1130-1137
- ISSN
- 0021-9738 (ISSN-L)
- PMC
- PMC1072700
- OpenAlex
- W2144097932
- Cited by
- 300
- References
- 35
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 7 · 2023: 2 · 2022: 6 · 2021: 10 · 2020: 7 · 2019: 9 · 2018: 10 · 2017: 13 · 2016: 9 · 2015: 5 · 2014: 11 · 2013: 9 · 2012: 11
- FWCI
- 4.26
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Health Sciences › Medicine › Physiology (medical) › Biomedical and Chemical Research
- Keywords
- cerebral blood flow, cerebral metabolic rate, children, reference values, cerebral circulation, pediatric neurophysiology
- MeSH terms
- Acclimatization, Brain, Cerebrovascular Circulation, Child, Humans, Nitrous Oxide, Reference Values
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review