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Cited by 221Lipid metabolism and disordersCholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

The DOI matches its Crossref record; 30 of the 32 references it cites were found in a registry or an index.

Kinetics of triglyceride turnover of very low density lipoproteins of human plasma

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Reaven, G M, Hill, D B, Gross, R C, Farquhar, J W·1965·Journal of Clinical Investigation
DOI 10.1172/jci105290PMC PMC289683
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Abstract

Ahrens and co-workers (1) have collated and extended prior observations (2-7) that high car- bohydrate, low fat diets may cause hypertriglyceridemia in certain subjects.They termed this phenomenon "carbohydrate-induced lipemia" (1).Despite uncertainties concerning the degree or duration of plasma triglyceride rise needed to merit this appellation, this general response to a high carbohydrate diet is frequently observed in patients with evidence for accelerated atherogenesis (1, 8-10).Furthermore, elevated plasma triglycerides are common in patients with "pre- mature" arteriosclerotic heart disease on ad libitum diets (11-16).Consequently, it becomes im- portant to define the factors controlling plasma triglyceride concentration in man.It can be assumed that changes in concentra- tion of water soluble macromolecules confined to the plasma space, such as lipoproteins, result from variations in rates of entry into and re- moval from plasma, or both.Hypertriglyceridemia in patients with "fat-induced lipemia," another and a relatively uncommon syndrome (1,

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Citations

Cites

Research works printed but not linked: 6

  1. Nichols, A. V., V. Dobbin, and J. W. Gofman. In- fluence of dietary factors upon human serum lipo- protein concentrations. Geriatrics 1957, 12, 7.
  2. Reaven, G. M., J. W. Farquhar, L. B. Salans, R. C. Gross, and R. M. Wagner. Carbohydrate-induced lipemia (abstract). Clin. Res. 1964, 12, 277.
  3. Reaven, G., A. Frank, R. Gross, L. Salans, and J. Farquhar. Glucose and insulin metabolism in car- bohydrate-induced lipemia (abstract). Clin. Res. 1965, 13, 332.
  4. Fredrickson, D. S., K. Ono, and L. L. Davis. Lipo- lytic activity of post-heparin plasma in hyper- glyceridemia. J. Lipid Res. 1963, 4, 24.
  5. Porte, D., Jr., D. D. O'Hara, and R. H. Williams. Low post-heparin lipolytic activity in myxedema (abstract). Clin. Res. 1965, 13, 108.
  6. Farquhar, J. W., R. C. Gross, P. W. Wright, and G. M. Reaven. Kinetics of plasma lipoprotein tri- glyceride in man and the dog (abstract). J. clin. Invest. 1965, 44, 1046.

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Metadata

Authors
Reaven, G. M., Hill, D. B., Gross, R. C., & Farquhar, J. W.
Affiliations
  • Stanford Medicine (US)
  • United States Public Health Service (US)
Venue
Journal of Clinical Investigation
Publisher
American Society for Clinical Investigation
Published
1965-11-01
Volume
44
Issue
11
Pages
1826-1833
ISSN
0021-9738 (ISSN-L)
DOI
10.1172/jci105290
PMC
PMC289683
OpenAlex
W1996392591
Cited by
221
References
32
Citations by year
2026: 1 · 2023: 2 · 2021: 1 · 2020: 1 · 2017: 1 · 2014: 1
FWCI
13.07
Type
journal article
Language
en
Open access
Locations
  • Journal of Clinical Investigation (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institutes of Health
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Keywords
VLDL, triglyceride turnover, hypertriglyceridemia, lipoprotein kinetics, atherogenesis, arteriosclerotic heart disease
MeSH terms
Adult, Female, Glycerides, Humans, Kinetics, Lipoproteins, Male, Middle Aged, Models, Theoretical, Lipid Metabolism

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