The DOI matches its Crossref record; 30 of the 32 references it cites were found in a registry or an index.
Kinetics of triglyceride turnover of very low density lipoproteins of human plasma
Open accessAbstract
Ahrens and co-workers (1) have collated and extended prior observations (2-7) that high car- bohydrate, low fat diets may cause hypertriglyceridemia in certain subjects.They termed this phenomenon "carbohydrate-induced lipemia" (1).Despite uncertainties concerning the degree or duration of plasma triglyceride rise needed to merit this appellation, this general response to a high carbohydrate diet is frequently observed in patients with evidence for accelerated atherogenesis (1, 8-10).Furthermore, elevated plasma triglycerides are common in patients with "pre- mature" arteriosclerotic heart disease on ad libitum diets (11-16).Consequently, it becomes im- portant to define the factors controlling plasma triglyceride concentration in man.It can be assumed that changes in concentra- tion of water soluble macromolecules confined to the plasma space, such as lipoproteins, result from variations in rates of entry into and re- moval from plasma, or both.Hypertriglyceridemia in patients with "fat-induced lipemia," another and a relatively uncommon syndrome (1,
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Plasma TG levels range from 0.33 to 120 mmol/L (30 to 10 000 mg/dL)13,17 (Figure 6), reflecting variability in the rates of secretion and clearance of TG and apoB in VLDL and chylomicrons.61,77”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
David, F. N., & Kendall, M. G. (1956) · Journal of the Royal Statistical Society Series A (General) · doi:10.2307/2342970 · Cited by 1,614
CLEARING FACTOR, A HEPARIN-ACTIVATED LIPOPROTEIN LIPASE
Korn, E. D. (1955) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)66011-9 · Cited by 858
THE INFLUENCE OF DIETARY FATS ON SERUM-LIPID LEVELS IN MAN
Ahrens, E., Insull, W., Blomstrand, R., Hirsch, J., Tsaltas, T. T., & Peterson, M. L. (1957) · The Lancet · doi:10.1016/s0140-6736(57)91280-1 · Cited by 726
Serum Triglycerides in Coronary Artery Disease
Albrink, M. J. (1959) · Archives of Internal Medicine · doi:10.1001/archinte.1959.00270010010002 · Cited by 466
CLEARING FACTOR, A HEPARIN-ACTIVATED LIPOPROTEIN LIPASE
Korn, E. D. (1955) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)66012-0 · Cited by 403
IDIOPATHIC HYPERLIPEMIA: METABOLIC STUDIES IN AN AFFECTED FAMILY*
Havel, R. J., & Gordon, R. S. (1960) · Journal of Clinical Investigation · doi:10.1172/jci104202 · Cited by 380
Carbohydrate-induced and fat-induced lipemia.
Eh, A., HIRSCH, J., Oette, K., Farquhar, J. W., & Stein, Y. (1961) · PubMed · Cited by 373
Self-citationLipolytic activity of post-heparin plasma in hyperglyceridemia
Fredrickson, D. S., Ono, K., & Davis, L. L. (1963) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)40361-x · Cited by 371
Sheppard, H. (1965) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600540147 · Cited by 347
Serum Lipids in Men with Myocardial Infarction
Carlson, L. A. (1960) · Acta Medica Scandinavica · doi:10.1111/j.0954-6820.1960.tb03562.x · Cited by 325
Research works printed but not linked: 6
- Nichols, A. V., V. Dobbin, and J. W. Gofman. In- fluence of dietary factors upon human serum lipo- protein concentrations. Geriatrics 1957, 12, 7.
- Reaven, G. M., J. W. Farquhar, L. B. Salans, R. C. Gross, and R. M. Wagner. Carbohydrate-induced lipemia (abstract). Clin. Res. 1964, 12, 277.
- Reaven, G., A. Frank, R. Gross, L. Salans, and J. Farquhar. Glucose and insulin metabolism in car- bohydrate-induced lipemia (abstract). Clin. Res. 1965, 13, 332.
- Fredrickson, D. S., K. Ono, and L. L. Davis. Lipo- lytic activity of post-heparin plasma in hyper- glyceridemia. J. Lipid Res. 1963, 4, 24.
- Porte, D., Jr., D. D. O'Hara, and R. H. Williams. Low post-heparin lipolytic activity in myxedema (abstract). Clin. Res. 1965, 13, 108.
- Farquhar, J. W., R. C. Gross, P. W. Wright, and G. M. Reaven. Kinetics of plasma lipoprotein tri- glyceride in man and the dog (abstract). J. clin. Invest. 1965, 44, 1046.
Cited by
Sorted by citations
Donnelly, K. L., Smith, C. I., Schwarzenberg, S. J., Jessurun, J., Boldt, M. D., & Parks, E. J. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23621 · Cited by 3,604
Fat Transport in Lipoproteins — An Integrated Approach to Mechanisms and Disorders
Fredrickson, D. S., Levy, R. I., & Lees, R. S. (1967) · New England Journal of Medicine · doi:10.1056/nejm196701052760107 · Cited by 1,911
Hatch, F. T., & Lees, R. S. (1968) · Advances in lipid research · doi:10.1016/b978-1-4831-9942-9.50008-5 · Cited by 1,235
Ginsberg, H. N., Packard, C. J., Chapman, M. J., Borén, J., Aguilar-Salinas, C. A., Averna, M., Ference, B. A., Gaudet, D., Hegele, R. A., Kersten, S., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab551 · Cited by 979
Parks, E. J., & Hellerstein, M. K. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.2.412 · Cited by 530
Metadata
- Authors
- Reaven, G. M., Hill, D. B., Gross, R. C., & Farquhar, J. W.
- Affiliations
- Stanford Medicine (US)
- United States Public Health Service (US)
- Venue
- Journal of Clinical Investigation
- Published
- 1965-11-01
- Volume
- 44
- Issue
- 11
- Pages
- 1826-1833
- ISSN
- 0021-9738 (ISSN-L)
- PMC
- PMC289683
- OpenAlex
- W1996392591
- Cited by
- 221
- References
- 32
- Citations by year
- 2026: 1 · 2023: 2 · 2021: 1 · 2020: 1 · 2017: 1 · 2014: 1
- FWCI
- 13.07
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Keywords
- VLDL, triglyceride turnover, hypertriglyceridemia, lipoprotein kinetics, atherogenesis, arteriosclerotic heart disease
- MeSH terms
- Adult, Female, Glycerides, Humans, Kinetics, Lipoproteins, Male, Middle Aged, Models, Theoretical, Lipid Metabolism
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
