Cited by 566Sexual Differentiation and DisordersAdrenal Hormones and DisordersMetabolism and Genetic Disorders

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17-Hydroxylation deficiency in man

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Biglieri, E G, Herron, M A, Brust, N·1966·Journal of Clinical Investigation

DOI 10.1172/jci105499PMC PMC292880

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Practical Physiological Chemistry
(1938) · JAMA · doi:10.1001/jama.1938.02790100062037 · Cited by 1,364
On the Enzymatic Determination of Blood Glucose
Raabo, B. E., & Terkildsen, T. C. (1960) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365516009065404 · Cited by 925
PRACTICAL PHYSIOLOGICAL CHEMISTRY
HAWK, P. B., Oser, B. L., & SUMMERSON, W. H. (1955) · The American Journal of the Medical Sciences · doi:10.1097/00000441-195507000-00025 · Cited by 908
THE DETERMINATION OF 17, 21-DIHYDROXY-20-KETOSTEROIDS IN URINE AND PLASMA
SILBER, R. H., & Porter, C. C. (1954) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)65419-5 · Cited by 779
ASSAY OF THE FOLLICLE STIMULATING HORMONE BASED ON THE AUGMENTATION WITH HUMAN CHORIONIC GONADOTROPIN
STEELMAN, S. L., & Pohley, F. M. (1953) · Endocrinology · doi:10.1210/endo-53-6-604 · Cited by 698
Double Isotope Derivative Assay of Aldosterone in Biological Extracts
Kliman, B., & Peterson, R. E. (1960) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)76855-0 · Cited by 592
An instrument and method for automatic, rapid, accurate, and sensitive titration of chloride in biologic samples.
Cotlove, E., Trantham, H. V., & Bowman, R. L. (1958) · PubMed · Cited by 427
NEW PROCEDURES FOR MEASUREMENT OF HUMAN PLASMA ANGIOTENSIN AND RENIN ACTIVITY LEVELS.
Boucher, R., Veyrat, R., de Champlain, J., & Genest, J. (1964) · PubMed Central · Cited by 401
AN IMMUNOCHEMICAL ASSAY OF TOTAL EXTRACTABLE INSULIN IN MAN *
Grodsky, G. M., & Forsham, P. H. (1960) · Journal of Clinical Investigation · doi:10.1172/jci104122 · Cited by 350
The adrenogenital syndrome with deficiency of 3β-hydroxysteroid dehydrogenase
Bongiovanni, A. M. (1962) · Journal of Clinical Investigation · doi:10.1172/jci104666 · Cited by 304

Show all 38 references

Research works printed but not linked: 3

[12]12. Riondel, A., J. F. Tait, S. A. S. Tait, M. Gut, and B. Little.' Estimation of progesterone in human peripheral blood using 'S-thiosemicarbazide. J. clin. Endocr. 1965, 25, 229.
[14]14. Horton, R. Estimation of androstenedione in human peripheral blood with 'S-thiosemicarbazide. J. clin. Endocr. 1965, 25, 1237.
[31]31. Biglieri, E. G., P. E. Slaton, Jr., W. S. Silen, M. Galante, and P. H. Forsham. Postoperative stud- ies of adrenal function in primary aldosteronism. J. clin. Endocr. 1966, 26, 553.

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Authors: Biglieri, E. G., Herron, M. A., & Brust, N.
Affiliations: San Francisco General Hospital (US)
Venue: Journal of Clinical Investigation
Publisher: American Society for Clinical Investigation
Published: 1966-12-01
Volume: 45
Issue: 12
Pages: 1946-1954
ISSN: 0021-9738 (ISSN-L)
DOI: 10.1172/jci105499
PMC: PMC292880
OpenAlex: W2025408018
Semantic Scholar: 4321404e8c055df66091f50f82aa9945d6208f8d
Cited by: 561
References: 38
Citations by year: 2026: 5 · 2025: 4 · 2024: 5 · 2023: 16 · 2022: 14 · 2021: 6 · 2020: 7 · 2019: 9 · 2018: 5 · 2017: 12 · 2016: 7 · 2015: 15 · 2014: 13 · 2013: 14 · 2012: 10
FWCI: 6.02
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Journal of Clinical Investigation (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Cisco Systems
National Institutes of Health
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Sexual Differentiation and Disorders
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Metabolism and Genetic Disorders
Keywords: congenital adrenal hyperplasia, steroidogenesis, adrenal cortex, 17-hydroxyprogesterone
MeSH terms: Adrenal Glands, Adrenocorticotropic Hormone, Adult, Corticosterone, Desoxycorticosterone, Diet, Sodium-Restricted, Female, Humans, Mixed Function Oxygenases, Hydroxyprogesterones, Metabolism, Inborn Errors, Metyrapone, Natriuresis, Potassium, Progesterone

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