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Cited by 436

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Frequency dependence of compliance as a test for obstruction in the small airways

Open access
Woolcock, Ann J., Vincent, N. J., Macklem, Peter T.·1969·Journal of Clinical Investigation

Abstract

We selected five bronchitics and four asthmatics in remission, whose routine lung function tests were not significantly abnormal. Dynamic compliance was measured at different respiratory frequencies and the results compared with those obtained from a normal control group. In all patients compliance was frequency dependent and remained so after the administration of bronchodilator aerosols. Compliance was frequency dependent in only one normal subject, and this was completely reversed by bronchodilators. Because the elastic properties of the patients' lungs were normal, and because pulmonary resistance was normal or only minimally increased, we interpret these results as indicating obstruction in peripheral airways.

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Metadata

Authors
Woolcock, A. J., Vincent, N. J., & Macklem, P. T.
Venue
Journal of Clinical Investigation
Published
1969-06-01
Volume
48
Issue
6
Pages
1097-1106
ISSN
0021-9738 (ISSN-L)
OpenAlex
W2111709698
Cited by
436
References
1
FWCI
53.06
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Frequency dependence of compliance as a test for obstruction in the small airways. https://app.cochat.ai/papers/10.1172/jci106066
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Woolcock, A. J., Vincent, N. J., & Macklem, P. T. (1969). Frequency dependence of compliance as a test for obstruction in the small airways. Journal of Clinical Investigation. https://doi.org/10.1172/jci106066

Data sources

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.