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Cited by 264

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Circadian rhythm in serum parathyroid hormone concentration in human subjects: correlation with serum calcium, phosphate, albumin, and growth hormone levels

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Jubiz, William, Canterbury, Janet M., Reiss, Eric, Tyler, Frank H.·1972·Journal of Clinical Investigation
DOI 10.1172/jci107010
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Abstract

A circadian variation in serum calcium, albumin and PTH concentration in normal subjects has been demonstrated. The levels of the three blood constituents were remarkably constant during the day, but striking night and early morning changes occurred. Serum calcium levels were highest at 8:00 p.m. and reached a nadir between 2:00 and 4:00 a.m. Serum albumin levels were parallel to those of serum calcium. PTH levels began to rise after 8:00 p.m., reached the highest levels between 2:00 and 4:00 a.m., and fell to baseline values by 8:00 a.m. The nocturnal fall in serum calcium levels appears to be secondary to dilution of serum proteins by increasing blood volume. The nocturnal rise in PTH levels appears to be independent of serum calcium levels within the normal range but it can be abolished by induced hypercalcemia. Serum phosphate levels were lowest between 8:00 a.m. and 10:00 a.m. and highest between 2:00 a.m. and 4:00 a.m. The data presented suggest that circadian changes in serum phosphate levels are not mediated in toto by parathyroid hormone but they are exaggerated when the secretion of this hormone is inhibited. They are independent of growth hormone levels and activity but they are greatly modified during a prolonged fast.

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Metadata

Authors
Jubiz, W., Canterbury, J. M., Reiss, E., & Tyler, F. H.
Venue
Journal of Clinical Investigation
Publisher
American Society for Clinical Investigation
Published
1972-08-01
Volume
51
Issue
8
Pages
2040-2046
ISSN
0021-9738 (ISSN-L)
DOI
10.1172/jci107010
OpenAlex
W2140458754
Cited by
264
References
15
FWCI
4.36
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Circadian rhythm in serum parathyroid hormone concentration in human subjects: correlation with serum calcium, phosphate, albumin, and growth hormone levels. https://app.cochat.ai/papers/10.1172/jci107010
The paper
Jubiz, W., Canterbury, J. M., Reiss, E., & Tyler, F. H. (1972). Circadian rhythm in serum parathyroid hormone concentration in human subjects: correlation with serum calcium, phosphate, albumin, and growth hormone levels. Journal of Clinical Investigation. https://doi.org/10.1172/jci107010

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.