The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
The electron transport chain of the microbicidal oxidase of phagocytic cells and its involvement in the molecular pathology of chronic granulomatous disease.
Open accessAbstract
The earliest experiments attempted to purify the oxidase from whole-cell homogenates and crude subcellular fractions.These were incubated with a variety of potential substrates in an attempt to demonstrate oxidase or diaphorase activity (5).The dramatic increase in the activity ofthe hexose monophosphate shunt in association with the respiratory burst (6) indicated one of its products, NADPH (7), as the most physiological of these substrates.A variety of activities were detected, but the
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Cites
Targeting the KEAP1-NRF2 system to prevent kidney disease progression
Nezu, M., Suzuki, N., & Yamamoto, M. (2017) · American Journal of Nephrology · doi:10.1159/000475890 · Cited by 3,447
Royer-Pokora, B., Kunkel, L. M., Monaco, A. P., Goff, S. C., Newburger, P. E., Baehner, R. L., Cole, F. S., Curnutte, J. T., & Orkin, S. H. (1986) · Nature · doi:10.1038/322032a0 · Cited by 833
Cross, A. R., & Jones, O. T. G. (1986) · Biochemical Journal · doi:10.1042/bj2370111 · Cited by 551
Parkos, C. A., Allen, R. A., Cochrane, C. G., & Jesaitis, A. J. (1987) · Journal of Clinical Investigation · doi:10.1172/jci113128 · Cited by 455
Two cytosolic neutrophil oxidase components absent in autosomal chronic granulomatous disease
Volpp, B. D., Nauseef, W. M., & Clark, R. A. (1988) · Science · doi:10.1126/science.2848318 · Cited by 407
Dinauer, M. C., Orkin, S. H., Brown, R., Jesaitis, A. J., & Parkos, C. A. (1987) · Nature · doi:10.1038/327717a0 · Cited by 407
Induction of phagocyte cytochrome b heavy chain gene expression by interferon gamma.
Newburger, P. E., Ezekowitz, R. A., Whitney, C., Wright, J., & Orkin, S. H. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.14.5215 · Cited by 140
Cited by
Strategies of antioxidant defense
SIES, H. (1993) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1993.tb18025.x · Cited by 1,976
Role of nitric oxide synthesis in macrophage antimicrobial activity
Nathan, C. F., & Hibbs, J. B. (1991) · Current Opinion in Immunology · doi:10.1016/0952-7915(91)90079-g · Cited by 1,523
The biochemical basis of the NADPH oxidase of phagocytes
Segal, A. W., & Abo, A. (1993) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(93)90051-n · Cited by 459
Self-citationTyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteins.
Heinecke, J. W., Li, W., Francis, G. A., & Goldstein, J. A. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116531 · Cited by 354
Segal, A. W., West, I., Wientjes, F., Nugent, J. H. A., Chavan, A. J., Haley, B., Garcia, R. C., Rosen, H., & Scrace, G. (1992) · Biochemical Journal · doi:10.1042/bj2840781 · Cited by 349
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Metadata
- Authors
- Segal, A. W.
- Venue
- Journal of Clinical Investigation
- Published
- 1989-06-01
- Volume
- 83
- Issue
- 6
- Pages
- 1785-1793
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W3023000517
- Cited by
- 284
- References
- 7
- FWCI
- 16.89
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Segal, A. W. (1989). The electron transport chain of the microbicidal oxidase of phagocytic cells and its involvement in the molecular pathology of chronic granulomatous disease. Journal of Clinical Investigation. https://doi.org/10.1172/jci114083
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
