The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Specific labelling of a component polypeptide of the oxidase

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961 · see citing works

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

Raza, H., John, A., & Nemmar, A. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350087 · Cited by 47,311 · see citing works

Oxygen-Dependent Microbial Killing by Phagocytes

BABIOR, B. M. (1978) · New England Journal of Medicine · doi:10.1056/nejm197803232981205 · Cited by 2,483 · see citing works

Oxidants from phagocytes: agents of defense and destruction

Babior, B. (1984) · Blood · doi:10.1182/blood.v64.5.959.959 · Cited by 804 · see citing works

Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44,000 protein

Segal, A. W., Heyworth, P. G., Cockcroft, S., & Barrowman, M. M. (1985) · Nature · doi:10.1038/316547a0 · Cited by 281 · see citing works

Characteristics of the cofactor requirements for the superoxide-generating NADPH oxidase of human polymorphonuclear leukocytes

Light, D. R., Walsh, C. T., O'Callaghan, A. M., Goetzl, E. J., & Tauber, A. I. (1981) · Biochemistry · doi:10.1021/bi00509a010 · Cited by 249 · see citing works

The enzymic reduction and kinetics of oxidation of cytochrome b.245 of neutrophils

Cross, A. R., Higson, F. K., Jones, O. T. G., Harper, A., & Segal, A. W. (1982) · Biochemical Journal · doi:10.1042/bj2040479 · Cited by 246 · see citing works

Oxidation-reduction properties of the cytochrome b found in the plasma-membrane fraction of human neutrophils. A possible oxidase in the respiratory burst

Cross, A. R., Jones, O. T., Harper, A., & Segal, A. W. (1981) · Biochemical Journal · doi:10.1042/bj1940599 · Cited by 229 · see citing works

Polymorphonuclear Leukocyte-Mediated, Antibody-Dependent, Cellular Cytotoxicity against Tumor Cells: Dependence on Oxygen and the Respiratory Burst

Hafeman, D. G., & Lucas, Z. J. (1979) · The Journal of Immunology · doi:10.4049/jimmunol.123.1.55 · Cited by 142 · see citing works

The superoxide-generating oxidase of leucocytes. NADPH-dependent reduction of flavin and cytochrome b in solubilized preparations

Cross, A. R., Parkinson, J. F., & Jones, O. T. G. (1984) · Biochemical Journal · doi:10.1042/bj2230337 · Cited by 136 · see citing works

Mechanism of the superoxide-producing oxidase of neutrophils. O2 is necessary for the fast reduction of cytochrome b-245 by NADPH

Cross, A. R., Parkinson, J. F., & Jones, O. T. G. (1985) · Biochemical Journal · doi:10.1042/bj2260881 · Cited by 128 · see citing works

Specific labelling of a constituent polypeptide of bovine heart mitochondrial reduced nicotinamide-adenine dinucleotide-ubiquinone reductase by the inhibitor diphenyleneiodonium

RAGAN, C. I., & Bloxham, D. P. (1977) · Biochemical Journal · doi:10.1042/bj1630605 · Cited by 115 · see citing works

The association of FAD with the cytochrome b–245 of human neutrophils

Cross, A. R., Jones, O. T. G., Garcia, R. C., & Segal, A. W. (1982) · Biochemical Journal · doi:10.1042/bj2080759 · Cited by 111 · see citing works

The NADPH-dependent O-.2-generating oxidase from human neutrophils.

Gabig, T. G. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)32416-5 · Cited by 105 · see citing works

Purification and partial characterization of the b-type cytochrome from human polymorphonuclear leukocytes.

Lutter, R., van Schaik, M. L., van Zwieten, R., Wever, R., Roos, D., & Hamers, M. N. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)89544-8 · Cited by 94 · see citing works

Purification of cytochrome b-245 from human neutrophils

Harper, A., Dunne, M. J., & Segal, A. W. (1984) · Biochemical Journal · doi:10.1042/bj2190519 · Cited by 89 · see citing works

Cytochrome b558 from (bovine) granulocytes. Partial purification from Triton X-114 extracts and properties of the isolated cytochrome.

Pember, S. O., Heyl, B. L., Kinkade, J. M., & Lambeth, J. D. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)91003-3 · Cited by 74 · see citing works

CHANGES IN THE METABOLIC PATTERN OF POLYMORPHO-NUCLEAR LEUCOCYTES DURING PHAGOCYTOSIS.

Rossi, F., & Zatti, M. (1964) · PubMed · Cited by 72 · see citing works

Activation of protein kinase C in neutrophil cytoplasts

Gennaro, R., Florio, C., & Romeo, D. (1985) · FEBS Letters · doi:10.1016/0014-5793(85)81068-1 · Cited by 66 · see citing works

The effects of diphenyleneiodonium on mitochondrial reactions. Relation of binding of diphenylene[125I]iodonium to mitochondria to the extent of inhibition of oxygen uptake

Gatley, S. J., & Sherratt, H. S. A. (1976) · Biochemical Journal · doi:10.1042/bj1580307 · Cited by 59 · see citing works

The Role of Particles in the Pathogenesis of Joint Disease

Dieppe, P. A., & Doherty, M. (1982) · Current topics in pathology · doi:10.1007/978-3-642-68382-4_7 · Cited by 24 · see citing works

The relationship of diphenyleneiodonium-induced hypoglycaemia to the specific covalent modification of nadh-ubiquinone oxidoreductase

BLOXHAM, D. P. (1979) · Biochemical Society Transactions · doi:10.1042/bst0070103 · Cited by 19 · see citing works

Nitric oxide synthases in mammals

Knowles, R. G., & Moncada, S. (1994) · Biochemical Journal · doi:10.1042/bj2980249 · Cited by 2,752 · see citing works

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

Papayannopoulos, V., Metzler, K. D., Hakkim, A., & Zychlinsky, A. (2010) · Journal of Cell Biology · doi:10.1083/jcb.201006052 · Cited by 2,103 · see citing works

Generation of reactive oxygen species by the mitochondrial electron transport chain

Liu, Y., Fiskum, G., & Schubert, D. (2002) · Journal of Neurochemistry · doi:10.1046/j.0022-3042.2002.00744.x · Cited by 1,260 · see citing works

Hydrogen peroxide and nitric oxide as signalling molecules in plants

Neill, S. J., Desikan, R., Clarke, A., Hurst, R. D., & Hancock, J. T. (2002) · Journal of Experimental Botany · doi:10.1093/jexbot/53.372.1237 · Cited by 1,218 · see citing works

Oxidants and human disease: some new concepts 1

Halliwell, B. B. (1987) · The FASEB Journal · doi:10.1096/fasebj.1.5.2824268 · Cited by 1,201 · see citing works

Killing activity of neutrophils is mediated through activation of proteases by K+ flux

Reeves, E. P., Lu, H., Jacobs, H. L., Messina, C. G. M., Bolsover, S., Gabella, G., Potma, E. O., Warley, A., Roes, J., & Segal, A. W. (2002) · Nature · doi:10.1038/416291a · Cited by 1,153 · see citing works

Organic Polyvalent Iodine Compounds

Stang, P. J., & Zhdankin, V. V. (1996) · Chemical Reviews · doi:10.1021/cr940424+ · Cited by 1,022 · see citing works

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

Drummond, G. R., Selemidis, S., Griendling, K. K., & Sobey, C. G. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3403 · Cited by 899 · see citing works

The superoxide-generating NADPH oxidase: structural aspects and activation mechanism

Vignais, P. V. (2002) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-002-8520-9 · Cited by 773 · see citing works

Voltage-Gated Proton Channels and Other Proton Transfer Pathways

DeCoursey, T. E. (2003) · Physiological Reviews · doi:10.1152/physrev.00028.2002 · Cited by 730 · see citing works

The O2−-forming NADPH oxidase of the phagocytes: nature, mechanisms of activation and function

Rossi, F. (1986) · Biochimica et Biophysica Acta (BBA) - Reviews on Bioenergetics · doi:10.1016/0304-4173(86)90005-4 · Cited by 656 · see citing works

Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance.

Münzel, T. F., Sayegh, H. S., Freeman, B. Α., Tarpey, M. M., & Harrison, D. G. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117637 · Cited by 652 · see citing works

Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase

O’Donnell, V. B., Tew, D. G., Jones, O. T. G., & ENGLAND, P. J. (1993) · Biochemical Journal · doi:10.1042/bj2900041 · Cited by 588 · see citing works

Abscisic Acid Activation of Plasma Membrane Ca2+ Channels in Guard Cells Requires Cytosolic NAD(P)H and Is Differentially Disrupted Upstream and Downstream of Reactive Oxygen Species Production in abi1-1 and abi2-1 Protein Phosphatase 2C Mutants

Murata, Y., Pei, Z., Mori, I. C., & Schroeder, J. I. (2001) · The Plant Cell · doi:10.1105/tpc.010210 · Cited by 579 · see citing works

Production of Reactive Oxygen Intermediates (O2 ˙ −, H2O2, and ˙ OH) by Maize Roots and Their Role in Wall Loosening and Elongation Growth

Krieger‐Liszkay, A., van der Zalm, E., & Schöpfer, P. (2004) · PLANT PHYSIOLOGY · doi:10.1104/pp.104.044784 · Cited by 572 · see citing works

The superoxide‐generating oxidase of phagocytic cells

Morel, F., Doussière, J., & Vignais, P. V. (1991) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1991.tb16312.x · Cited by 562 · see citing works

NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets

Zhang, Y., Murugesan, P., Huang, K., & Cai, H. “. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0260-8 · Cited by 546 · see citing works

Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation

Tejero, J., Shiva, S., & Gladwin, M. T. (2019) · Physiological Reviews · doi:10.1152/physrev.00036.2017 · Cited by 541 · see citing works

Ozone-Sensitive Arabidopsis rcd1 Mutant Reveals Opposite Roles for Ethylene and Jasmonate Signaling Pathways in Regulating Superoxide-Dependent Cell Death

Overmyer, K., Tuominen, H., Kettunen, R., Betz, C., Langebartels, C., Sandermann, H., & Kangasjärvi, J. (2000) · The Plant Cell · doi:10.1105/tpc.12.10.1849 · Cited by 532 · see citing works

ABA, hydrogen peroxide and nitric oxide signalling in stomatal guard cells

Desikan, R. (2003) · Journal of Experimental Botany · doi:10.1093/jxb/erh033 · Cited by 515 · see citing works

Regulation of Nox and Duox enzymatic activity and expression

Lambeth, J. D., Kawahara, T., & Diebold, B. A. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.03.028 · Cited by 498 · see citing works

The NADPH oxidase of professional phagocytes—prototype of the NOX electron transport chain systems

Cross, A. R., & Segal, A. W. (2004) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2004.03.008 · Cited by 489 · see citing works

Transmigrating Neutrophils Shape the Mucosal Microenvironment through Localized Oxygen Depletion to Influence Resolution of Inflammation

Campbell, E. L., Bruyninckx, W. J., Kelly, C. J., Glover, L. E., McNamee, E. N., Bowers, B., Bayless, A. J., Scully, M. M., Saeedi, B. J., Golden‐Mason, L., et al. (2014) · Immunity · doi:10.1016/j.immuni.2013.11.020 · Cited by 472 · see citing works

Diphenyleneiodonium, an NAD(P)H Oxidase Inhibitor, also Potently Inhibits Mitochondrial Reactive Oxygen Species Production

Li, Y., & Trush, M. A. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9729 · Cited by 470 · see citing works

Enzymic mechanisms of superoxide production

Cross, A. R., & Jones, O. T. G. (1991) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(05)80140-9 · Cited by 468 · see citing works

Endothelium-Derived Hyperpolarizing Factor Synthase (Cytochrome P450 2C9) Is a Functionally Significant Source of Reactive Oxygen Species in Coronary Arteries

Fleming, I., Michaelis, U. R., Bredenkötter, D., Fisslthaler, B., Dehghani, F., Brandes, R. P., & Busse, R. (2001) · Circulation Research · doi:10.1161/01.res.88.1.44 · Cited by 440 · see citing works

Early signaling components in ultraviolet‐B responses: distinct roles for different reactive oxygen species and nitric oxide

A.‐H.‐Mackerness, S., John, C. F., Jordan, B. R., & Thomas, B. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)02103-2 · Cited by 419 · see citing works

Analysis and Effects of Cytosolic Free Calcium Increases in Response to Elicitors in Nicotiana plumbaginifolia Cells

Lecourieux, D., Mazars, C., Pauly, N., Ranjeva, R., & Pugin, A. (2002) · The Plant Cell · doi:10.1105/tpc.005579 · Cited by 403 · see citing works

Endothelial Mitochondria: Contributing to Vascular Function and Disease

Davidson, S. M., & Duchen, M. R. (2007) · Circulation Research · doi:10.1161/01.res.0000261970.18328.1d · Cited by 381 · see citing works

Cytochrome b 558 : the Flavin-Binding Component of the Phagocyte NADPH Oxidase

Rotrosen, D., Yeung, C. L., Leto, T. L., Malech, H. L., & Kwong, C. H. (1992) · Science · doi:10.1126/science.1318579 · Cited by 378 · see citing works

Dihydrorhodamine 123: a fluorescent probe for superoxide generation?

HENDERSON, L. M., & Chappell, J. (1993) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1993.tb18328.x · Cited by 368 · see citing works

The Mitochondrial Network of Human Neutrophils: Role in Chemotaxis, Phagocytosis, Respiratory Burst Activation, and Commitment to Apoptosis

Fossati, G., MOULDING, D. A., Spiller, D. G., Moots, R. J., White, M., & Edwards, S. W. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.170.4.1964 · Cited by 348 · see citing works

The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel

HENDERSON, L. M., Chappell, J., & Jones, O. T. G. (1987) · Biochemical Journal · doi:10.1042/bj2460325 · Cited by 334 · see citing works

Guard‐cell signalling for hydrogen peroxide and abscisic acid

Wang, P., & Song, C. (2008) · New Phytologist · doi:10.1111/j.1469-8137.2008.02431.x · Cited by 323 · see citing works

Hydrogen Peroxide Is Involved in Collagen-Induced Platelet Activation

Pignatelli, P., Pulcinelli, F. M., Lenti, L., Gazzaniga, P. P., & Violi, F. (1998) · Blood · doi:10.1182/blood.v91.2.484 · Cited by 322 · see citing works

The voltage dependence of NADPH oxidase reveals why phagocytes need proton channels

DeCoursey, T. E., Morgan, D., & Cherny, V. V. (2003) · Nature · doi:10.1038/nature01523 · Cited by 318 · see citing works

Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase. A new action for an old drug.

Münzel, T. F., Kurz, S. D., Rajagopalan, S., Thoenes, M., Berrington, W. R., Thompson, J. A., Freeman, B. Α., & Harrison, D. G. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118935 · Cited by 313 · see citing works

The superoxide-forming enzymatic system of phagocytes

Bellavite, P. (1988) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(88)90044-5 · Cited by 312 · see citing works

Diversity in Mitochondrial Function Explains Differences in Vascular Oxygen Sensing

Michelakis, E. D., Hampl, V., Nsair, A., Wu, X., Harry, G., Haromy, A., Gurtu, R., & Archer, S. L. (2002) · Circulation Research · doi:10.1161/01.res.0000024689.07590.c2 · Cited by 309 · see citing works

Reactive oxygen species generation by human spermatozoa is induced by exogenous NADPH and inhibited by the flavoprotein inhibitors diphenylene iodonium and quinacrine

Aitken, R. J., Fisher, H. M., Fulton, N., Gómez, E., Knox, W., Lewis, B., & Irvine, S. (1997) · Molecular Reproduction and Development · doi:10.1002/(sici)1098-2795(199708)47:4 · Cited by 303 · see citing works

Regulation of Protein-Tyrosine Phosphorylation and Human Sperm Capacitation by Reactive Oxygen Derivatives

Leclerc, P., de Lamirande, E., & Gagnon, C. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00379-6 · Cited by 294 · see citing works

Volatile signalling by sesquiterpenes from ectomycorrhizal fungi reprogrammes root architecture

Ditengou, F. A., Müller, A., Rosenkranz, M., Felten, J., Lasok, H., van Doorn, M. M., Legué, V., Palme, K. J., Schnitzler, J., & Polle, A. (2015) · Nature Communications · doi:10.1038/ncomms7279 · Cited by 291 · see citing works

Plasma Membrane Redox Enzyme Is Involved in the Synthesis of O2- and H2O2 by Phytophthora Elicitor-Stimulated Rose Cells

Auh, C., & Murphy, T. M. (1995) · PLANT PHYSIOLOGY · doi:10.1104/pp.107.4.1241 · Cited by 283 · see citing works

The electron transport chain of the microbicidal oxidase of phagocytic cells and its involvement in the molecular pathology of chronic granulomatous disease.

Segal, A. W. (1989) · Journal of Clinical Investigation · doi:10.1172/jci114083 · Cited by 282 · see citing works

Comparative Biochemistry of the Oxidative Burst Produced by Rose and French Bean Cells Reveals Two Distinct Mechanisms1

Bolwell, G. P., Davies, D. R., Gerrish, C., Auh, C., & Murphy, T. M. (1998) · PLANT PHYSIOLOGY · doi:10.1104/pp.116.4.1379 · Cited by 281 · see citing works

Plant Respiratory Burst Oxidase Homologs Impinge on Wound Responsiveness and Development inLycopersicon esculentum [W]

Sagi, M., Davydov, O., Orazova, S., Yesbergenova, Z., Ophir, R., Stratmann, J. W., & Fluhr, R. (2004) · The Plant Cell · doi:10.1105/tpc.019398 · Cited by 278 · see citing works

Early Events Induced by the Elicitor Cryptogein in Tobacco Cells: Involvement of a Plasma Membrane NADPH Oxidase and Activation of Glycolysis and the Pentose Phosphate Pathway

Pugin, A., Frachisse, J., Tavernier, E., Bligny, R., Gout, E., Douce, R., & Guern, J. (1997) · The Plant Cell · doi:10.1105/tpc.9.11.2077 · Cited by 266 · see citing works

Endothelial NADPH Oxidase as the Source of Oxidants in Lungs Exposed to Ischemia or High K +

Al‐Mehdi, A. B., Zhao, G., Dodia, C., Tozawa, K., Costa, K., Muzykantov, V. R., Ross, C. R., Blecha, F., Dinauer, M. C., & Fisher, A. B. (1998) · Circulation Research · doi:10.1161/01.res.83.7.730 · Cited by 264 · see citing works

O 2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase

Archer, S. L., Reeve, H. L., Michelakis, E. D., Puttagunta, L., Waite, R. E., Nelson, D. P., Dinauer, M. C., & Weir, Ε. K. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.14.7944 · Cited by 260 · see citing works

Pulmonary Artery NADPH-Oxidase is Activated in Hypoxic Pulmonary Vasoconstriction

Marshall, C., Mamary, A. J., Verhoeven, A. J., & Marshall, B. E. (1996) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.15.5.8918370 · Cited by 256 · see citing works

Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line

Morgan, D., Oliveira-Emilio, H. R., Keane, D., Hirata, A. E., Rocha, M., Bordin, S. A., Curi, R., Newsholme, P., & Carpinelli, Â. R. (2006) · Diabetologia · doi:10.1007/s00125-006-0462-6 · Cited by 252 · see citing works

Superoxide Production in Galleria mellonella Hemocytes: Identification of Proteins Homologous to the NADPH Oxidase Complex of Human Neutrophils

Bergin, D. A., Reeves, E. P., Renwick, J. A. A., Wientjes, F. B., & Kavanagh, K. A. (2005) · Infection and Immunity · doi:10.1128/iai.73.7.4161-4170.2005 · Cited by 250 · see citing works

Involvement of NADPH Oxidase Isoforms and Src Family Kinases in CD95-dependent Hepatocyte Apoptosis

Reinehr, R., Becker, S., Eberle, A., Grether‐Beck, S., & Häussinger, D. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m414361200 · Cited by 246 · see citing works

Small-Molecule NOX Inhibitors: ROS-Generating NADPH Oxidases as Therapeutic Targets

Jaquet, V., Scapozza, L., Clark, R. A., Krause, K. H., & Lambeth, J. D. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2585 · Cited by 243 · see citing works

NADPH oxidases in the vasculature: Molecular features, roles in disease and pharmacological inhibition

Selemidis, S., Sobey, C. G., Wingler, K., Schmidt, H. H. H. W., & Drummond, G. R. (2008) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2008.08.005 · Cited by 241 · see citing works

The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation

Di, A., Gao, X.-P., Qian, F., Kawamura, T., Han, J., Hecquet, C. M., Ye, R. D., Vogel, S. M., & Malik, A. B. (2011) · Nature Immunology · doi:10.1038/ni.2171 · Cited by 238 · see citing works

Oxygen Free Radicals and Platelet Activation

Iuliano, L., Colavita, A. R., Leo, R., Praticò, D., & Violi, F. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00488-1 · Cited by 235 · see citing works

IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis

Iannitti, R. G., Napolioni, V., Oikonomou, V., LUCA, A. D., Galosi, C., Pariano, M., Massi-Benedetti, C., Borghi, M., Puccetti, M., Lucidi, V., et al. (2016) · Nature Communications · doi:10.1038/ncomms10791 · Cited by 233 · see citing works

Superoxide anion is a natural inhibitor of FAS‐mediated cell death.

Clement, M., & Stamenkovic, I. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00352.x · Cited by 233 · see citing works

Identification of a superoxide-generating NADPH oxidase system in human fibroblasts

Meier, B., Cross, A. R., Hancock, J. T., Kaup, F. ‐., & Jones, O. T. G. (1991) · Biochemical Journal · doi:10.1042/bj2750241 · Cited by 229 · see citing works

The Respiratory Burst Oxidase

BABIOR, B. M. (1992) · Advances in enzymology and related areas of molecular biology/Advances in enzymology and related subjects · doi:10.1002/9780470123119.ch2 · Cited by 220 · see citing works

Oxygen sensors in context

Ward, J. P. T. (2007) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2007.10.010 · Cited by 219 · see citing works

Subcellular localization of ozone‐induced hydrogen peroxide production in birch (Betula pendula) leaf cells

Pellinen, R., Palva, T. E., & Kangasjärvi, J. (1999) · The Plant Journal · doi:10.1046/j.1365-313x.1999.00613.x · Cited by 219 · see citing works

Nox enzymes as novel targets for drug development

Lambeth, J. D., Krause, K.-H., & Clark, R. A. (2008) · Seminars in Immunopathology · doi:10.1007/s00281-008-0123-6 · Cited by 212 · see citing works

The inhibition by diphenyleneiodonium and its analogues of superoxide generation by macrophages

Hancock, J. T., & Jones, O. T. (1987) · Biochemical Journal · doi:10.1042/bj2420103 · Cited by 208 · see citing works

Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor

Hirano, K., Chen, W. S., Chueng, A. L. W., Dunne, A. A., Seredenina, T., Filippova, A., Ramachandran, S., Bridges, A., Chaudry, L., Pettman, G., et al. (2015) · Antioxidants & Redox Signaling · doi:10.1089/ars.2014.6202 · Cited by 205 · see citing works

NADPH oxidase of neutrophils

HENDERSON, L. M., & Chappell, J. (1996) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(95)00140-9 · Cited by 205 · see citing works

Classical Inhibitors of NOX NAD(P)H Oxidases Are Not Specific

Aldieri, E., Riganti, C., Polimeni, M., Gazzano, E., Lussiana, C., Campia, I., & Ghigo, D. (2008) · Current Drug Metabolism · doi:10.2174/138920008786049285 · Cited by 201 · see citing works

Electron currents generated by the human phagocyte NADPH oxidase

Schrenzel, J., Serrander, L., Bánfi, B., Nüße, O., Foyouzi-Youssefi, R., Lew, D. P., Demaurex, N., & Krause, K. (1998) · Nature · doi:10.1038/33725 · Cited by 201 · see citing works

Scavenging reactive oxygen species selectively inhibits M2 macrophage polarization and their pro-tumorigenic function in part, via Stat3 suppression

Griess, B., Mir, S. U. R., Datta, K., & Teoh-Fitzgerald, M. L. T. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.12.018 · Cited by 200 · see citing works

Diphenyleneiodonium inhibits reduction of iron-sulfur clusters in the mitochondrial NADH-ubiquinone oxidoreductase (Complex I).

Majander, A. S., Finel, M., & Wikström, M. K. F. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)31926-9 · Cited by 200 · see citing works

Involvement of an NAD(P)H oxidase as a pO2 sensor protein in the rat carotid body

Cross, A. R., HENDERSON, L. M., Jones, O. T. G., Delpiano, M. A., Hentschel, J., & Acker, H. (1990) · Biochemical Journal · doi:10.1042/bj2720743 · Cited by 199 · see citing works

Diphenyleneiodonium Inhibits the Cell Redox Metabolism and Induces Oxidative Stress

Riganti, C., Gazzano, E., Polimeni, M., Costamagna, C., Bosìa, A., & Ghigo, D. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m406314200 · Cited by 198 · see citing works

Inhibition of NADPH Oxidase Activation by 4-(2-Aminoethyl)-benzenesulfonyl Fluoride and Related Compounds

Diatchuk, V., Lotan, O., Koshkin, V., Wikstroem, P., & Pick, E. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.20.13292 · Cited by 195 · see citing works

Transgenic tobacco expressing a foreign calmodulin gene shows an enhanced production of active oxygen species

Harding, S. A., Oh, S., & Roberts, D. M. (1997) · The EMBO Journal · doi:10.1093/emboj/16.6.1137 · Cited by 194 · see citing works

NADPH oxidase is an O 2 sensor in airway chemoreceptors: Evidence from K + current modulation in wild-type and oxidase-deficient mice

Fu, X., Wang, D., Nurse, C. A., Dinauer, M. C., & Cutz, E. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.8.4374 · Cited by 192 · see citing works

Pharmacological characterization of the seven human NOX isoforms and their inhibitors

Augsburger, F., Филиппова, А., Rasti, D., Seredenina, T. S., Lam, M. A., Maghzal, G. J., Mahiout, Z., Jansen‐Dürr, P., Knaus, U. G., Doroshow, J. H., et al. (2019) · Redox Biology · doi:10.1016/j.redox.2019.101272 · Cited by 191 · see citing works

NADPH oxidase activity is required for endothelial cell proliferation and migration

Abid, M. R., Kachra, Z., Spokes, K., & Aird, W. C. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)02305-x · Cited by 191 · see citing works

Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells

Lambertucci, R. H., Hirabara, S. M., Silveira, L. R., Levada‐Pires, A. C., Curi, R., & Pithon‐Curi, T. C. (2008) · Journal of Cellular Physiology · doi:10.1002/jcp.21463 · Cited by 187 · see citing works

Pancreatic β-Cells Express Phagocyte-Like NAD(P)H Oxidase

Oliveira, H. R., Verlengia, R., Carvalho, C. R. D. O., Britto, L. R., Curi, R., & Carpinelli, Â. R. (2003) · Diabetes · doi:10.2337/diabetes.52.6.1457 · Cited by 186 · see citing works

Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

Kolpen, M., Hansen, C. R., Bjarnsholt, T., Moser, C. E., Christensen, L., van Gennip, M., Ciofu, O., Mandsberg, L. F., Kharazmi, A., Döring, G., et al. (2009) · Thorax · doi:10.1136/thx.2009.114512 · Cited by 185 · see citing works

Hypoxia/reoxygenation-mediated induction of astrocyte interleukin 6: a paracrine mechanism potentially enhancing neuron survival.

Maeda, Y., Matsumoto, M., Hori, O., Kuwabara, K., Ogawa, S., Yan, S. D., Ohtsuki, T., Kinoshita, T., Kamada, T., & Stern, D. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.180.6.2297 · Cited by 185 · see citing works

K+ channels and the microglial respiratory burst

Khanna, R., Roy, L., Zhu, X., & Schlichter, L. C. (2001) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.2001.280.4.c796 · Cited by 182 · see citing works

Internal pH changes associated with the activity of NADPH oxidase of human neutrophils. Further evidence for the presence of an H+ conducting channel

HENDERSON, L. M., Chappell, J., & Jones, O. T. G. (1988) · Biochemical Journal · doi:10.1042/bj2510563 · Cited by 179 · see citing works

Regulation of Apical Dominance in Aspergillus nidulans Hyphae by Reactive Oxygen Species

Semighini, C. P., & Harris, S. D. (2008) · Genetics · doi:10.1534/genetics.108.089318 · Cited by 178 · see citing works

N -Glycosylation of Effector Proteins by an α-1,3-Mannosyltransferase Is Required for the Rice Blast Fungus to Evade Host Innate Immunity

Chen, X., Shi, T., Yang, J., Shi, W., Gao, X., Chen, D., Xu, X., Xu, J., Talbot, N. J., & Peng, Y. (2014) · The Plant Cell · doi:10.1105/tpc.114.123588 · Cited by 176 · see citing works

Processing and Maturation of Flavocytochromeb 558 Include Incorporation of Heme as a Prerequisite for Heterodimer Assembly

DeLeo, F. R., Burritt, J. B., Yu, L., Jesaitis, A. J., Dinauer, M. C., & Nauseef, W. M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.18.13986 · Cited by 176 · see citing works

Free Radicals and Antioxidant Protection: Mechanisms and Significance in Toxicology and Disease

Halliwell, B. B., & Gutteridge, J. M. C. (1988) · Human Toxicology · doi:10.1177/096032718800700102 · Cited by 176 · see citing works

Lymphocyte Migration Through Monolayers of Endothelial Cell Lines Involves VCAM-1 Signaling Via Endothelial Cell NADPH Oxidase

Matheny, H. E., Deem, T. L., & Cook‐Mills, J. M. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.12.6550 · Cited by 173 · see citing works

Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generation

Morand, S. C., Ueyama, T., Tsujibe, S., Saito, N., Korzeniowska, A., & Leto, T. L. (2008) · The FASEB Journal · doi:10.1096/fj.08-120006 · Cited by 171 · see citing works

Ellagic acid inhibits oxidized LDL-mediated LOX-1 expression, ROS generation, and inflammation in human endothelial cells

Lee, W., Ou, H., Hsu, W.-C., Chou, M., Tseng, J., Hsu, S., Tsai, K., & Sheu, W. H. (2010) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2010.04.085 · Cited by 166 · see citing works

The effect of the NADPH oxidase inhibitor diphenyleneiodonium on aerobic and anaerobic microbicidal activities of human neutrophils

Ellis, J. A., Mayer, S. J., & Jones, O. T. G. (1988) · Biochemical Journal · doi:10.1042/bj2510887 · Cited by 164 · see citing works

Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis

Hattori, H., Subramanian, K. K., Sakai, J., Jia, Y., Li, Y., Porter, T. F., Loison, F., Sarraj, B., Kasorn, A., Jo, H., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914351107 · Cited by 162 · see citing works

NADPH oxidase: a universal oxygen sensor?

Jones, R. D., Hancock, J. T., & Morice, A. H. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00320-8 · Cited by 162 · see citing works

Solubilization and Separation of a Plant Plasma Membrane NADPH-O2- Synthase from Other NAD(P)H Oxidoreductases

Gestelen, P. V., Asard, H., & Caubergs, R. J. (1997) · PLANT PHYSIOLOGY · doi:10.1104/pp.115.2.543 · Cited by 160 · see citing works

Yeast β-glucan stimulates respiratory burst activity of Atlantic salmon (Salmo salar L.) macrophages

Jørgensen, J. B., & Robertsen, B. (1995) · Developmental & Comparative Immunology · doi:10.1016/0145-305x(94)00045-h · Cited by 160 · see citing works

Analysis of Dichlorodihydrofluorescein and Dihydrocalcein as Probes for the Detection of Intracellular Reactive Oxygen Species

Keller, A., Mohamed, A., Dröse, S., Brandt, U., Fleming, I., & Brandes, R. P. (2004) · Free Radical Research · doi:10.1080/10715760400022145 · Cited by 157 · see citing works

The respiratory burst oxidase

BABIOR, B. M. (1995) · Current Opinion in Hematology · doi:10.1097/00062752-199502010-00008 · Cited by 157 · see citing works

The inhibitory effects of some iodonium compounds on the superoxide generating system of neutrophils and their failure to inhibit diaphorase activity

Cross, A. R. (1987) · Biochemical Pharmacology · doi:10.1016/0006-2952(87)90356-x · Cited by 58 · see citing works

NADPH binding component of neutrophil superoxide-generating oxidase.

Umei, T., Takeshige, K., & Minakami, S. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)57201-5 · Cited by 61 · see citing works

Purification and some properties of the 45 kDa diphenylene iodonium-binding flavoprotein of neutrophil NADPH oxidase

Yea, C., Cross, A. R., & Jones, O. T. G. (1990) · Biochemical Journal · doi:10.1042/bj2650095 · Cited by 62 · see citing works

Diphenylene iodonium as an inhibitor of the NADPH oxidase complex of bovine neutrophils: Factors controlling the inhibitory potency of diphenylene iodonium in a cell‐free system of oxidase activation

DOUSSIÈRE, J., & VIGNAIS, P. V. (1992) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1992.tb17159.x · Cited by 153 · see citing works

The inhibition by diphenyleneiodonium and its analogues of superoxide generation by macrophages

Hancock, J. T., & Jones, O. T. (1987) · Biochemical Journal · doi:10.1042/bj2420103 · Cited by 208 · see citing works