The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes.
Open accessAbstract
Vascular cell adhesion molecule-1 (VCAM-1), an inducible cell-cell recognition protein on the endothelial cell surface (EC), has been associated with early stages of atherosclerosis. In view of the accelerated vascular disease observed in patients with diabetes, and the enhanced expression of VCAM-1 in diabetic rabbits, we examined whether irreversible advanced glycation endproducts (AGEs), could mediate VCAM-1 expression by interacting with their endothelial cell receptor (receptor for AGE, RAGE). Exposure of cultured human ECs to AGEs induced expression of VCAM-1, increased adhesivity of the monolayer for Molt-4 cells, and was associated with increased levels of VCAM-1 transcripts. The inhibitory effect of anti-RAGE IgG, a truncated form of the receptor (soluble RAGE) or N-acetylcysteine on VCAM-1 expression indicated that AGE-RAGE-induced oxidant stress was central to VCAM-1 induction. Electrophoretic mobility shift assays on nuclear extracts from AGE-treated ECs showed induction of specific DNA binding activity for NF-kB in the VCAM-1 promoter, which was blocked by anti-RAGE IgG or N-acetylcysteine. Soluble VCAM-1 antigen was elevated in human diabetic plasma. These data are consistent with the hypothesis that AGE-RAGE interaction induces expression of VCAM-1 which can prime diabetic vasculature for enhanced interaction with circulating monocytes.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Excessive AGE formation is particularly associated with cross-linking of matrix proteins such as collagen, vitronectin, and laminin.[2,10,11]”
From The Role of Dietary Advanced Glycation End Products in Metabolic Dysfunction (2021) · cites this paper as [11]
In the citing paper
“Binding of AGEs to the receptor for AGE (RAGE) enhances the expression of adhesion molecules on endothelial cells to promote the migration and differentiation of monocytes into macrophages.”
From The Vasculature in Prediabetes (2018) · cites this paper as [60]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
Chirgwin, J. M., Przybyla, A., MacDonald, R. J., & Rutter, W. J. (1979) · Biochemistry · doi:10.1021/bi00591a005 · Cited by 21,460
Jaffe, E. A., Nachman, R., Becker, C. G., & Minick, C. (1973) · Journal of Clinical Investigation · doi:10.1172/jci107470 · Cited by 7,146
Schreiber, E. H., Matthias, P., Müller, M. M., & Schaffner, W. (1989) · Nucleic Acids Research · doi:10.1093/nar/17.15.6419 · Cited by 4,179
Schreck, R., RIEBER, P., & Baeuerle, P. A. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07761.x · Cited by 3,793
Role of Oxidative Stress in Development of Complications in Diabetes
Baynes, J. (1991) · Diabetes · doi:10.2337/diab.40.4.405 · Cited by 3,791
Advanced Glycosylation End Products in Tissue and the Biochemical Basis of Diabetic Complications
Flier, J. S., Underhill, L. H., Brownlee, M., Cerami, A., & Vlassara, H. (1988) · New England Journal of Medicine · doi:10.1056/nejm198805193182007 · Cited by 2,512
Endothelial Expression of a Mononuclear Leukocyte Adhesion Molecule During Atherogenesis
Cybulsky, M. I., & Gimbrone, M. A. (1991) · Science · doi:10.1126/science.1990440 · Cited by 1,710
Neeper, M. P., Schmidt, A. M., Brett, J., Yan, S. D., Wang, F., Pan, Y., Elliston, K. O., Stern, D., & SHAW, A. R. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42138-2 · Cited by 1,545
Self-citationYan, S. D., Schmidt, A. M., Anderson, G. M., Zhang, J., Brett, J., Zou, Y., Pinsky, D. J., & Stern, D. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36966-1 · Cited by 1,305
Self-citationCytokines and endothelial cell biology
Pober, J. S., & Cotran, R. S. (1990) · Physiological Reviews · doi:10.1152/physrev.1990.70.2.427 · Cited by 1,251
Flagged first, then by citations
Cited by
Sorted by citations
Items 501–600 of 893
Shen, Y. H., Dai, Y., Wang, X. Q., Zhang, R., Lu, L., Ding, F. H., & Shen, W. F. (2019) · Cardiovascular Diabetology · doi:10.1186/s12933-019-0959-1 · Cited by 32
Race-Specific Differences in Antioxidant Enzyme Activity in Patients With Type 2 Diabetes
Zitouni, K., Nourooz‐Zadeh, J., Harry, D. S., Kerry, S., Betteridge, D. J., Cappuccio, F. P., & Earle, K. (2005) · Diabetes Care · doi:10.2337/diacare.28.7.1698 · Cited by 30
Effect of gliclazide on monocyte–endothelium interactions in diabetes
Renier, G., Desfaits, A.-C., & Serri, O. (2000) · Journal of Diabetes and its Complications · doi:10.1016/s1056-8727(00)00082-9 · Cited by 30
Ido, Y., Chang, K. C., LeJeune, W. S., Bjercke, R. J., Reiser, K. M., Williamson, J. R., & Tilton, R. G. (2001) · Microcirculation · doi:10.1111/j.1549-8719.2001.tb00174.x · Cited by 30
Zhang, F., Gao, H., & Shen, L. (2007) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0b013e3181342bfa · Cited by 29
Mahali, S. K., Verma, N., & Manna, S. K. (2014) · Journal of Cellular Physiology · doi:10.1002/jcp.24647 · Cited by 30
Involvement of HMGB1 and RAGE in IL-1β-induced gingival inflammation
Ito, Y., BHAWAL, U. K., Sasahira, T., Toyama, T., Sato, T., Matsuda, D., Nishikiori, H., Kobayashi, M., Sugiyama, M., Hamada, N., et al. (2011) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2011.08.001 · Cited by 29
Singhania, N., Puri, D., Madhu, S. V., & Sharma, S. B. (2008) · QJM · doi:10.1093/qjmed/hcn020 · Cited by 28
Interaction of β1-adrenoceptor with RAGE mediates cardiomyopathy via CaMKII signaling
Zhu, W., Tsang, S., Browe, D. M., Woo, A. Y., Huang, Y. R., Xu, C., Liu, J., Lv, F., Zhang, Y., & Xiao, R. (2016) · JCI Insight · doi:10.1172/jci.insight.84969 · Cited by 29
Caterina, R. D., Bourcier, T., Laufs, U., Fata, V. L., Lazzerini, G., Neish, A. S., Libby, P., & Liao, J. K. (2001) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.21.2.227 · Cited by 29
Grdina, D. J., Murley, J. S., Kataoka, Y., & Calvin, D. P. (2002) · Seminars in Radiation Oncology · doi:10.1053/srao.2002.31383 · Cited by 29
Pallayová, M., Banerjee, D., & Taheri, S. (2014) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2014.01.007 · Cited by 28
Lee, J., Hyon, J., Min, J. Y., Huh, Y. H., Kim, H. J., Lee, H., Yun, S. H., Choi, C.-W., Ha, S. J., Park, J., et al. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.104600 · Cited by 28
Complications of Diabetes Mellitus
Brownlee, M., Aiello, L. P., Cooper, M. E., Vinik, A. I., Plutzky, J., & Boulton, A. J. M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-29738-7.00033-2 · Cited by 29
Carroll, L., Hannawi, S., Marwick, T. H., & Thomas, R. (2006) · Wiener Medizinische Wochenschrift · doi:10.1007/s10354-005-0242-9 · Cited by 28
Diabetic RBC-induced oxidant stress leads to transendothelial migration of monocyte-like HL-60 cells
Rattan, V., Shen, Y. M., Sultana, C., Kumar, D. B. U., & Kalra, V. K. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.273.2.e369 · Cited by 28
New Aspects of Vascular Calcification: Histone Deacetylases and Beyond
Kwon, D., Kim, Y., & Kook, H. Y. (2017) · Journal of Korean Medical Science · doi:10.3346/jkms.2017.32.11.1738 · Cited by 27
Nishizawà, Y., & Koyama, H. (2007) · Journal of Renal Nutrition · doi:10.1053/j.jrn.2007.10.016 · Cited by 28
Nakano, N., Takaki, K., Jono, T., Nakajou, K., Eto, N., Horiuchi, S., Takeya, M., & Nagai, R. (2006) · The Journal of Biochemistry · doi:10.1093/jb/mvj092 · Cited by 27
Chen, J., Brodsky, S. V., Li, H., Hampel, D. J., Miyata, T., Weinstein, T., Gafter, U., Norman, J. T., Fine, L. G., & Goligorsky, M. S. (2001) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.2001.281.1.f71 · Cited by 27
Self-citationGliclazide reduces the induction of human monocyte adhesion to endothelial cells by glycated albumin
Desfaits, A.-C., Serri, O., & Renier, G. (1999) · Diabetes Obesity and Metabolism · doi:10.1046/j.1463-1326.1999.00012.x · Cited by 27
Hui, Y. Y., McAmis, W., Baynes, J., Schaeffer, R. C., & Wolf, M. B. (2001) · Diabetologia · doi:10.1007/s001250100646 · Cited by 27
Chocholatý, M., Jáchymová, M., Schmidt, M., Havlová, K., Křepelová, A., Zima, T., Babjuk, M. M., & Kalousová, M. (2014) · Tumor Biology · doi:10.1007/s13277-014-2821-0 · Cited by 26
Yang, C., DeVisser, A., Martinez, J. A., Poliakov, I., Rosales-Hernandez, A., Ayer, A. B., Garven, A., Zaver, S., Rincon, N., Xu, K., et al. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.02.007 · Cited by 25
Self-citationRetractedSTAT5 Activation Induced by Diabetic LDL Depends on LDL Glycation and Occurs Via src Kinase Activity
Brizzi, M. F., Dentelli, P., Gambino, R., Cabodi, S., Cassader, M., Castelli, A., Defilippi, P., Pegoraro, L., & Pagano, G. (2002) · Diabetes · doi:10.2337/diabetes.51.11.3311 · Cited by 26
The receptor for advanced glycation end products mediates lung endothelial activation by RBCs
Mangalmurti, N. S., Friedman, J. L., Wang, L.-C., Stolz, D. B., Muthukumaran, G., Siegel, D. L., Schmidt, A. M., Lee, J. S., & Albelda, S. Μ. (2012) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00278.2012 · Cited by 25
Self-citationYou, J., Peng, W., Lin, X., Huang, Q., & Lin, J. (2010) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2010.01.036 · Cited by 25
Siddiqi, A., Zafar, S., Sharma, A., & Quaranta, A. A. (2019) · Australian Dental Journal · doi:10.1111/adj.12721 · Cited by 25
Anti-Inflammatory Properties of C-Peptide
Haidet, J., Cifarelli, V., Trucco, M., & Luppi, P. (2009) · The Review of Diabetic Studies · doi:10.1900/rds.2009.6.168 · Cited by 25
Matsunaga, N., Anan, I., Forsgren, S., Nagai, R., Rosenberg, P. M., Horiuchi, S., Ando, Y., & Suhr, O. B. (2002) · Acta Neuropathologica · doi:10.1007/s00401-002-0574-0 · Cited by 24
Barbieri, L., Verdoia, M., Schaffer, A., Cassetti, E., Giovine, G. D., Marino, P. N., Suryapranata, H., & Luca, G. D. (2014) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2014.09.041 · Cited by 24
Deronic, A., Helmersson, S., Leanderson, T., & Ivars, F. (2013) · International Immunopharmacology · doi:10.1016/j.intimp.2013.12.008 · Cited by 23
Murakami, H., Tamasawa, N., Matsui, J., Yamato, K., JingZhi, G., & Suda, T. (2001) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat1994.8.21 · Cited by 24
Therapeutic Effectiveness of Anti-RAGE Antibody Administration in a Rat Model of Crush Injury
Matsumoto, H., Matsumoto, N., Shimazaki, J., Nakagawa, J., Imamura, Y., Yamakawa, K., Yamada, T., Ikeda, M., Hiraike, H., Ogura, H., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-12065-4 · Cited by 24
Endogenous Secretory RAGE as a Novel Biomarker for Metabolic Syndrome and Cardiovascular Diseases
Koyama, H., Yamamoto, H., & Nishizawà, Y. (2007) · Biomarker Insights · doi:10.1177/117727190700200021 · Cited by 30
Endogenous Secretory RAGE as a Novel Biomarker for Metabolic Syndrome and Cardiovascular Diseases.
Koyama, H., Yamamoto, H., & Nishizawà, Y. (2007) · PubMed Central · Cited by 24
Hájek, Z., Germanová, A., Koucký, M., Zima, T., Kopecky, P., Vítkova, M., Pařı́zek, A., & Kalousová, M. (2008) · Journal of Perinatal Medicine · doi:10.1515/jpm.2008.080 · Cited by 24
Molecular Mechanisms of Diabetic Angiopathy – Clues for Innovative Therapeutic Interventions
Bierhaus, A., Ziegler, R., & Nawroth, P. P. (1998) · Hormone Research in Paediatrics · doi:10.1159/000053094 · Cited by 24
The RAGE/multiligand axis: a new actor in tumor biology
Armando Rojas, R., Schneider, I., Lindner, C., González, I., & Morales, M. A. (2022) · Bioscience Reports · doi:10.1042/bsr20220395 · Cited by 24
Zhou, L., Miranda, G. F., Chen, S., Neis, M., Hu, Z., Zhu, R., Li, Y., Prömpers, M., Offenhäusser, A., & Mayer, D. (2023) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2023.133730 · Cited by 24
The Role of Glucosamine-Induced ER Stress in Diabetic Atherogenesis
Beriault, D. R., & Werstuck, G. H. (2012) · Experimental Diabetes Research · doi:10.1155/2012/187018 · Cited by 21
Calycosin entered HUVECs and ameliorated AGEs-promoted cell apoptosis via the Bcl-2 pathway
Xu, Y., Xiong, J., Wang, S., Tang, D., Wang, R.-S., & Zhu, Q. (2013) · Journal of Natural Medicines · doi:10.1007/s11418-013-0787-7 · Cited by 23
Albumin inhibits adipogenesis and stimulates cytokine release from human adipocytes
Schlesinger, J. B., van Harmelen, V., Alberti-Huber, C., & Hauner, H. (2006) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00172.2005 · Cited by 23
The Pathogenic Role of the Adaptive Immune Response to Modified LDL in Diabetes
Virella, G., & Lopes-Virella, M. F. (2012) · Frontiers in Endocrinology · doi:10.3389/fendo.2012.00076 · Cited by 22
Saito, S., & Shibata, M. (2012) · 日本林學會誌 · doi:10.4005/jjfs.94.223 · Cited by 22
Lancefield, T. F., Patel, S. K., Freeman, M., Velkoska, E., Wai, B., Srivastava, P., Horrigan, M., Farouque, O., & Burrell, L. M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0161715 · Cited by 22
Ahmed, K. A., Muniandy, S., & Ismail, I. S. (2009) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.08-190 · Cited by 22
Advanced Glycation End Products Acutely Impair Ca2+ Signaling in Bovine Aortic Endothelial Cells
Naser, N., Januszewski, A. S., Brown, B. E., Jenkins, A. J., Hill, M. A., & Murphy, T. V. (2013) · Frontiers in Physiology · doi:10.3389/fphys.2013.00038 · Cited by 21
Gliclazide decreases low-density lipoprotein oxidation and monocyte adhesion to the endothelium
Renier, G., Desfaits, A.-C., & Serri, O. (2000) · Metabolism · doi:10.1016/s0026-0495(00)80080-3 · Cited by 22
Мухаррамовна, Б. Г., Oshitari, T., Baba, T., & Yamamoto, S. (2015) · Journal of Diabetes Research · doi:10.1155/2015/543818 · Cited by 22
McNair, E. D., Wells, C. R., Qureshi, A. M., Basran, R., Pearce, C., Orvold, J., Devilliers, J., & Prasad, K. (2010) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-010-0444-3 · Cited by 21
Advanced Glycation End Products (AGEs) in Diabetic Complications
Bhat, S., Mary, S., Giri, A. P., & Kulkarni, M. J. (2017) · Springer eBooks · doi:10.1007/978-3-319-60324-7_19 · Cited by 21
Inflammatory effects of in vivo glycated albumin from cardiovascular patients
Paradela‐Dobarro, B., Bravo, S. B., Rozados-Luís, A., González‐Peteiro, M., Roman, A. V., González‐Juanatey, J. R., García‐Seara, J., & Álvarez, E. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.108763 · Cited by 21
Metformin inhibits monocyte adhesion to endothelial cells and foam cell formation
Mamputu, J., Wiernsperger, N. F., & Renier, G. (2003) · The British Journal of Diabetes · doi:10.1177/14746514030030041501 · Cited by 21
Yoshizawa, M., Nagai, Y., OHSAWA, K., Ohta, M., Yamashita, H., Hisada, A., Miyamoto, I., Miura, K., Takamura, T., & KOBAYASHI, K. P. (1998) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(98)00091-6 · Cited by 21
Diabetes and other coronary heart disease risk equivalents
James, R. W. (2001) · Current Opinion in Lipidology · doi:10.1097/00041433-200108000-00009 · Cited by 20
E-selectin-inducing activity in plasma from type 2 diabetic patients with maculopathy
Knudsen, S. T., Foss, C. H., Poulsen, P. L., Bek, T., Ledet, T., Mogensen, C. E., & Rasmussen, L. M. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00198.2002 · Cited by 21
Transcardiac gradient of soluble adhesion molecules predicts progression of coronary artery disease
Yamamoto, H., Uemura, S., Tomoda, Y., Fujimoto, S., Hashimoto, T., & Okuchi, K. (2002) · International Journal of Cardiology · doi:10.1016/s0167-5273(02)00156-0 · Cited by 21
Gliclazide treatment lowers serum ICAM-1 levels in poorly controlled type 2 diabetic patients
Papanas, N., Tziakas, D. N., Chalikias, G. K., Floros, D., Trypsianis, G. A., Papadopoulou, E., Kortsaris, A., Symeonidis, G., Souliou, E., Maltezos, E. S., et al. (2006) · Diabetes & Metabolism · doi:10.1016/s1262-3636(07)70289-6 · Cited by 20
DiNorcia, J., Moroziewicz, D. N., Ippagunta, N., Lee, M. K., Foster, M., Rotterdam, H. Z., Bao, F., Zhou, Y. S., Yan, S. F., Emond, J. C., et al. (2010) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-010-1347-z · Cited by 21
Self-citationVlassopoulos, A., Lean, M. E. J., & Combet, E. (2014) · Proceedings of The Nutrition Society · doi:10.1017/s0029665114000603 · Cited by 20
Liu, C.-Y., Zhao, Z., Chen, Z., Che, C., Zou, Z., Wu, X., Chen, S., Li, Y., Lin, H., Wei, X.-F., et al. (2017) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2017.4784 · Cited by 20
Diabetic Retinopathy and Nephropathy
Klein, R. (2007) · Humana Press eBooks · doi:10.1007/978-1-59745-153-6_27 · Cited by 20
Kalousová, M., Jáchymová, M., Germanová, A., Kuběna, A. A., Tesař, V., & Zima, T. (2010) · Kidney & Blood Pressure Research · doi:10.1159/000285845 · Cited by 20
Yan, S. F., Yan, S. D., Herold, K. C., Ramsamy, R., & Schmidt, A. M. (2006) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2006.06.003 · Cited by 20
Self-citationElevation of N-(Carboxymethyl)valine Residue in Hemoglobin of Diabetic Patients
Uchimura, T., Nakano, K., Hashiguchi, T., Iwamoto, H., Miura, K., Yoshimura, Y., Hanyu, N., Hirata, K., Imakuma, M., Motomiya, Y., et al. (2001) · Diabetes Care · doi:10.2337/diacare.24.5.891 · Cited by 20
Expression of receptors for advanced glycation end-products in occlusive vascular and renal disease
Bierhaus, A., Ritz, E., & Nawroth, P. P. (1996) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/11.supp5.87 · Cited by 20
Monocyte adhesion in diabetic angiopathy
Renier, G., Mamputu, J., Desfaits, A.-C., & Serri, O. (2003) · Journal of Diabetes and its Complications · doi:10.1016/s1056-8727(02)00271-4 · Cited by 19
Chello, M., Spadaccio, C., Lusini, M., Covino, E., Blarzino, C., Marco, F. D., Domenico, F. D., & Coccia, R. (2009) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.966 · Cited by 19
Likhari, T., & Gama, R. M. (2010) · Journal of Clinical Pathology · doi:10.1136/jcp.2009.065821 · Cited by 19
Guo, X., HUANG, Q., Chen, B., Wang, S., Li, Q., ZHU, Y., Hou, F. F., FU, N., Brunk, U. T., & Zhao, M. F. (2006) · Apmis · doi:10.1111/j.1600-0463.2006.apm_372.x · Cited by 19
RetractedMasseau, I., & Bowles, D. K. (2015) · Journal of Biomedical Science and Engineering · doi:10.4236/jbise.2015.811073 · Cited by 19
Lee, H. M., Kim, H. J., Won, K., Choi, W. S., Park, S. H., Song, H., Park, P., Park, T.-K., Lee, C., & Kim, B. (2008) · Journal of Vascular Research · doi:10.1159/000112941 · Cited by 19
Crauwels, H. M. (2000) · Cardiovascular Research · doi:10.1016/s0008-6363(00)00090-0 · Cited by 19
Feasibility of using hyperosmolar mannitol as a liquid tumor embolization agent.
Feng, L., Kienitz, B. A., Matsumoto, C., Bruce, J. N., Sisti, M. B., Duong, H., & Pile‐Spellman, J. (2005) · PubMed Central · Cited by 19
Kageyama, Y., Takahashi, M., Nagafusa, T., Torikai, E., & Nagano, A. (2007) · Modern Rheumatology · doi:10.1007/s10165-007-0607-6 · Cited by 18
Ahmad, S., & Farhan, M. (2016) · Advances in neurobiology · doi:10.1007/978-3-319-28383-8_8 · Cited by 18
Neuropathy induced by exogenously administered advanced glycation end‐products in rats
Nishizawa, Y., Wada, R., Baba, M., Takeuchi, M., Hanyu‐Itabashi, C., & Yagihashi, S. (2010) · Journal of Diabetes Investigation · doi:10.1111/j.2040-1124.2009.00002.x · Cited by 18
Kneyber, M. C. J., Gazendam, R. P., Niessen, H. W. M., Kuiper, J.-W., dos Santos, C. C., Slutsky, A. S., & Plötz, F. B. (2009) · Critical Care · doi:10.1186/cc7911 · Cited by 18
Weerakoon, B. S., & Osuga, T. (2015) · Journal of Biomedical Science and Engineering · doi:10.4236/jbise.2015.811075 · Cited by 18
Čolak, E., & Majkić‐Singh, N. (2009) · Journal of Medical Biochemistry · doi:10.2478/v10011-009-0006-y · Cited by 16
Mesangial accumulation of GA-pyridine, a novel glycolaldehyde-derived AGE, in human renal disease
Greven, W. L., Waanders, F., Nagai, R., van den Heuvel, M. C., Navis, G. J., & van Goor, H. (2005) · Kidney International · doi:10.1111/j.1523-1755.2005.00437.x · Cited by 18
Future Horizons in Cardiovascular Molecular Therapeutics
Dzau, V. J., Gibbons, G. H., Mann, M. J., & Braun-Dullaeus, R. (1997) · The American Journal of Cardiology · doi:10.1016/s0002-9149(97)00790-x · Cited by 18
Mahali, S. K., & Manna, S. K. (2012) · Biochemical Pharmacology · doi:10.1016/j.bcp.2012.09.033 · Cited by 17
N-(Carboxymethyl)lysine induces γ-glutamylcysteine synthetase in RAW264.7 cells
Miyahara, Y., Ikeda, S., Muroya, T., Yasuoka, C., Urata, Y., Horiuchi, S., Kohno, S., & Kondo, T. (2002) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)00816-1 · Cited by 17
Felicetti, F., Cento, A. S., Fornengo, P., Cassader, M., Mastrocola, R., D'Ascenzo, F., Settanni, F., Benso, A. S., Arvat, E., Collino, M., et al. (2019) · Pediatric Blood & Cancer · doi:10.1002/pbc.28106 · Cited by 18
Sato, E., Nagaoka, T., Yokota, H., Takahashi, A., & Yoshida, A. (2012) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2011.10.020 · Cited by 17
Bastek, J. A., Brown, A. G., Foreman, M. N., McShea, M. A., Anglim, L. M., Adamczak, J. E., & Elovitz, M. A. (2012) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2012.663825 · Cited by 17
Li, R., Zhao, W.-W., & Gao, B. (2018) · Neural Regeneration Research · doi:10.4103/1673-5374.235249 · Cited by 17
Abdallah, H. M., Zakaria, E. M., Halawany, A. M. E., Mohamed, G. A., Safo, M. K., & El‐Bassossy, H. M. (2019) · PLoS ONE · doi:10.1371/journal.pone.0222101 · Cited by 17
The effect of serum albumin level on iron-induced oxidative stress in chronic renal failure patients
Sezer, M. T., Akın, H., Demir, M., Ertürk, J., Aydın, Z. D., Şavik, E., & Tunc, N. (2007) · Journal of Nephrology · doi:10.1093/joneph/20.2.196 · Cited by 17
Exercise and oxidative stress in diabetes mellitus
Laaksonen, D. E., Atalay, M., NISKANEN, L. K., Uusitupa, M. I. J., Hänninen, O., & Sen, C. K. (1998) · Pathophysiology · doi:10.1016/s0928-4680(98)80721-9 · Cited by 17
Inflammation, diabetic foot and related treatments
Qin, Y., & Deng, S. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1676621 · Cited by 20
Rempel, L. C. T., Becker-Finco, A., Maciel, R. A. P., Bosquetti, B., Alvarenga, L. M., de Souza, W. M., Pecoits‐Filho, R., & Stinghen, A. E. M. (2015) · Toxins · doi:10.3390/toxins7051722 · Cited by 16
Cardiovascular Risk Evaluated by C-Reactive Protein Levels in Diabetic and Obese Mexican Subjects
Flores‐Alfaro, E., Parra‐Rojas, I., Salgado-Bernabé, A. B., Chávez‐Maldonado, J. P., & Salazar-Martı́nez, E. (2008) · Circulation Journal · doi:10.1253/circj.72.1170 · Cited by 16
Cysteine/Glutathione Deficiency: A Significant and Treatable Corollary of Disease
Ghezzi, P., Lemley, K. V., Andrus, J. P., Rosa, S. C. D., Holmgren, A., Jones, D. P., Jahoor, F., Kopke, R. D., Cotgreave, I. A., Bottiglieri, T., et al. (2018) · Springer eBooks · doi:10.1007/978-981-10-5311-5_20 · Cited by 18
Soluble adhesion molecules levels in patients with Cushing’s syndrome before and after cure
Ermetici, F., Malavazos, A. E., Corbetta, S., Eller-Vainicher, C., Cannavò, S., Corsi, M. M., & Ambrosi, B. (2008) · Journal of Endocrinological Investigation · doi:10.1007/bf03346381 · Cited by 16
Heiston, E. M., & Malin, S. K. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-12668-1_15 · Cited by 17
Peschel, T., & Niebauer, J. (2003) · Cytometry Part B Clinical Cytometry · doi:10.1002/cyto.b.10026 · Cited by 16
Complications of Diabetes Mellitus
Brownlee, M., Aiello, L. P., Cooper, M. E., Vinik, A. I., Nesto, R. W., & Boulton, A. J. M. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-0324-5.00033-x · Cited by 16
Metadata
- Authors
- Schmidt, A. M., Hori, O., Chen, J. X., Li, J. F., Crandall, J., Zhang, J., Cao, R., Yan, S. D., Brett, J., & Stern, D.
- Affiliations
- Columbia University Irving Medical Center (US)
- Columbia University (US)
- Venue
- Journal of Clinical Investigation
- Published
- 1995-09-01
- Volume
- 96
- Issue
- 3
- Pages
- 1395-1403
- ISSN
- 0021-9738 (ISSN-L)
- PMC
- PMC185762
- OpenAlex
- W2138928713
- Cited by
- 896
- References
- 43
- Citations by year
- 2026: 5 · 2025: 11 · 2024: 15 · 2023: 16 · 2022: 13 · 2021: 21 · 2020: 16 · 2019: 23 · 2018: 16 · 2017: 26 · 2016: 17 · 2015: 34 · 2014: 32 · 2013: 35 · 2012: 36
- FWCI
- 17.32
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- KU ScholarWorks (University of Kansas) (submittedVersion, other-oa)
- Funders
- American Heart Association
- National Institutes of Health (5r01hl042833-10, 5p50hl021006-17)
- U.S. Public Health Service
- National Institute on Aging (AG00602)
- National Heart, Lung, and Blood Institute (HL-42833, HL 21006)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Advanced Glycation End Products research
- Health Sciences › Medicine › Immunology and Allergy › Cell Adhesion Molecules Research
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Keywords
- advanced glycation end products, receptor for advanced glycation end products, VCAM-1, endothelial cells, diabetes mellitus, diabetic vascular disease, oxidative stress, NF-kB, soluble RAGE, N-acetylcysteine, monocyte adhesion, atherosclerosis, soluble VCAM-1
- MeSH terms
- Receptor for Advanced Glycation End Products, Animals, Base Sequence, Cell Adhesion, Cell Line, Cell Nucleus, Cells, Cultured, Diabetic Angiopathies, Endothelium, Vascular, Enzyme-Linked Immunosorbent Assay, Humans, Male, Models, Biological, Molecular Sequence Data, Receptors, Immunologic, Transcription, Genetic, Umbilical Veins, Cell Adhesion Molecules, Gene Expression, Polymerase Chain Reaction, Glycation End Products, Advanced, DNA Primers, Oxidative Stress, Vascular Cell Adhesion Molecule-1, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
