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Cited by 435

The DOI matches its OpenAlex record; 42 of the 42 references it cites were found in a registry or an index.

Mechanisms for the induction of autoimmunity by infectious agents

Open access
Kai W. Wucherpfennig·2001·Journal of Clinical Investigation

Abstract

Autoimmune diseasesActivation and clonal expansion of autoreactive lymphocytes is a critical step in the pathogenesis of autoimmune diseases.In experimental models of autoimmunity, disease can be transferred by activated, but not resting, autoreactive T cells (1), indicating that activation of autoreactive T cells is required for the development of autoimmune diseases.Infectious agents have long been considered as possible culprits in the activation of autoreactive T cells.Mechanisms by which an infection can lead to an autoimmune process have been examined in experimental animal models, and these concepts as well as their relevance to human diseases will be discussed here.

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Metadata

Authors
Wucherpfennig, K. W.
Venue
Journal of Clinical Investigation
Publisher
American Society for Clinical Investigation
Published
2001-10-15
Volume
108
Issue
8
Pages
1097-1104
ISSN
0021-9738 (ISSN-L)
OpenAlex
W2135373024
Cited by
435
References
42
FWCI
5.72
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Mechanisms for the induction of autoimmunity by infectious agents. https://app.cochat.ai/papers/10.1172/jci14235
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Wucherpfennig, K. W. (2001). Mechanisms for the induction of autoimmunity by infectious agents. Journal of Clinical Investigation. https://doi.org/10.1172/jci14235

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.