The DOI matches its OpenAlex record; 42 of the 42 references it cites were found in a registry or an index.
Mechanisms for the induction of autoimmunity by infectious agents
Open accessAbstract
Autoimmune diseasesActivation and clonal expansion of autoreactive lymphocytes is a critical step in the pathogenesis of autoimmune diseases.In experimental models of autoimmunity, disease can be transferred by activated, but not resting, autoreactive T cells (1), indicating that activation of autoreactive T cells is required for the development of autoimmune diseases.Infectious agents have long been considered as possible culprits in the activation of autoreactive T cells.Mechanisms by which an infection can lead to an autoimmune process have been examined in experimental animal models, and these concepts as well as their relevance to human diseases will be discussed here.
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Cited by
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Metadata
- Authors
- Wucherpfennig, K. W.
- Venue
- Journal of Clinical Investigation
- Publisher
- American Society for Clinical Investigation
- Published
- 2001-10-15
- Volume
- 108
- Issue
- 8
- Pages
- 1097-1104
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W2135373024
- Cited by
- 435
- References
- 42
- FWCI
- 5.72
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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