Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight
DOI 10.1172/jci25977
Cited by (569)
Items 401–500 of 569
- Energy Balance, Myostatin, and GILZ: Factors Regulating Adipocyte Differentiation in Belly and BoneXingming Shi, Mark W. Hamrick, Carlos M. Isales · 2007 · PPAR Research
- Insensitivity of well-conditioned mature sheep to central administration of a leptin receptor antagonistAndreas Foskolos, Richard Ehrhardt, Stanley M. Hileman, Arieh Gertler, Yves R. Boisclair · 2015 · animal
- Hypocaloric Dieting Unsettles the Neuroenergetic Homeostasis in HumansEwelina K. Wardzinski, Carolin Hyzy, Kai Duysen, Uwe H. Melchert, Kamila Jauch‐Chara, Kerstin M. Oltmanns · 2021 · Nutrients
- Effect of Leptin Levels of Type 2 Diabetes Mellitus and Diabetic ComplicationsJingzhu Nan, Xu Zhang, Xu Zhang, Diangeng Li, Meiling Jin, Guang‐Hong Guo, Jin Dong, Xiujuan Li · 2022 · Clinical and investigative medicine
- Brain Reorganization following Weight LossMICHAEL S. ROSENBAUM, Rudolph L. Leibel · 2012 · Nestlé Nutrition Institute Workshop series
- Leptin and ObesityYuanyuan Zhang, Jun Tao Ren · 2015 · Springer eBooks
- Low-dose leptin infusion in the fourth ventricle of rats enhances the response to third-ventricle leptin injectionRuth B. S. Harris · 2017 · American Journal of Physiology-Endocrinology and Metabolism
- The Midwest Exercise Trial for the Prevention of Weight Regain: MET POWeRAmanda N. Szabo‐Reed, Richard A. Washburn, Debra K. Sullivan, Jeffery J. Honas, Matthew S. Mayo, Jeannine R. Goetz, Jae‐Hoon Lee, Joseph E. Donnelly · 2013 · Contemporary Clinical Trials
- Pharmacologic Treatments for the Preservation of Lean Body Mass During Weight LossGunjan Arora, Katherine R. Conde, Cyrus V Desouza · 2026 · Journal of Clinical Medicine
- Physiology of the Weight-Reduced State and Its Impact on Weight RegainSamar Hafida, Caroline Margaret Apovian · 2022 · Endocrinology and Metabolism Clinics of North America
- Structures of human protein tyrosine phosphatase variants reveal targetable allosteric sitesAliki Perdikari, Virgil A. Woods, Ali Ebrahim, Katherine Lawler, Rebecca Bounds, Dinesh Singh Shah, Nathanael I. Singh, Tamar Skaist Mehlman, Blake T. Riley, Shivani Sharma et al. · 2025 · Journal of Biological Chemistry
- Obesity research in the next decadeRobert H. Eckel · 2008 · International Journal of Obesity
- Identification of adipose tissue transcriptomic memory of anorexia nervosaRizaldy C. Zapata, Chanond A. Nasamran, Daisy Chilin-Fuentes, Stephanie C. Dulawa, Olivia Osborn · 2023 · Molecular Medicine
- Relationship between estimated fatty acid desaturase activities and abdominal adiposity in Japanese childrenEmiko Saito, Tomoo Okada, Yuriko Abe, Minako Odaka, Yuki Kuromori, Fujihiko Iwata, Mitsuhiko Hara, Hideo Mugishima, Yohei Kitamura · 2013 · Obesity Research & Clinical Practice
- Metabolic Consequences of Weight ReductionMICHAEL S. ROSENBAUM · 2012 · Wiley eBooks
- Systematic Review: Does Exercise Training Influence Ghrelin Levels?W. Abassi, N. Ouerghi, Antonella Muscella, S. Marsigliante, Moncef Feki, A. Bouassida · 2025 · International Journal of Molecular Sciences
- Metabolic and appetitive regulation of adipocyte mass during treatment of obesityJonathan Q. Purnell, Carel Wynand le Roux · 2025 · Journal of Internal Medicine
- The impact of a low‐carbohydrate (vs. low‐fat) diet on fat mass loss in African American women is modulated by insulin sensitivityCátia Martins, David R. Bryan, S. Katherine Sweatt, William Timothy Garvey, Kevin R. Fontaine, Gareth R. Dutton, Barbara Ann Gower · 2025 · Obesity
- Thyroid and Lipid Status in Guide Dogs During Training: Effects of Dietary Protein and Fat ContentBiagina Chiofalo, Esterina Fazio, Salvatore Cucinotta, Cristina Cravana · 2019 · Animals
- Growth hormone regulates neuroendocrine responses to weight loss via AgRP neuronsIsadora C. Furigo, Pryscila DS Teixeira, Souza Gabriel O de, Gisele C. L. Couto, Guadalupe García Romero, Mario Perelló, Renata Frazão, Lucila Leico Kagohara Elias, Martin Metzger, Edward Owen List et al. · 2019 · Yearbook of pediatric endocrinology
- Association of Serum Adipokines and Resting Energy Expenditure in Patients With Chronic Kidney DiseaseNanzha Abi, Xiao Xu, Zhikai Yang, Tiantian Ma, Jie Dong · 2022 · Frontiers in Nutrition
- Are gastrointestinal signals the principal guides to human appetite and energy balance?Katarina T. Borer · 2023 · Medical Research Archives
- Effects of the central melanocortin system on feed intake, metabolic hormones and insulin action in the sheepRichard Ehrhardt, Sarah L. Giesy, Stanley M. Hileman, Karen L. Houseknecht, Yves R. Boisclair · 2023 · Journal of Animal Science
- Strategies to Counter Weight Loss-Induced Reductions in Metabolic RateBiff F. Palmer, Deborah J. Clegg · 2019 · Current Sports Medicine Reports
- Leptin and G-protein coupled receptor (GPCR) signaling: Therapeutic potential in obesityXun Sun, Lincoln Brueck, Dongming Yang, Patrick L. Sheets, Baohua Zhou, Hongxia Ren · 2025 · Journal of Biological Chemistry
- Metabolic signature of short‐term low energy availabilityValentin Nußer, Chaise A. Murphy, Sieglinde Hechenbichler Figueroa, Alexander Braunsperger, Johanna Kaarina Ihalainen, Juha J. Hulmi, Paulina Wasserfurth, Karsten Koehler · 2025 · Physiological Reports
- Recombinant Human Leptin Does Not Alter Gut Hormone Levels after Gastric Bypass but May Attenuate Sweet CravingsRushika Conroy, Gerardo Febres, Donald J. McMahon, Michael O. Thorner, Bruce D. Gaylinn, Irene M. Conwell, Louis J. Aronne, Judith Körner · 2014 · International Journal of Endocrinology
- Management of Weight Regain Following Bariatric Surgery: Behavioral Intervention and PharmacotherapySarah R. Barenbaum, Alice S. Zhao, Katherine H. Saunders, Louis J. Aronne, Alpana P. Shukla · 2022 · Expert Review of Endocrinology & Metabolism
- Adipose tissue and sustainable development: a connection that needs protectionAngelo Tremblay, Éliane Picard‐Deland, Shirin Panahi, André Marette · 2015 · Frontiers in Pharmacology
- Nutrigenomics of Body Weight Regulation: A Rationale for Careful Dissection of Individual ContributorsJaap Keijer, Femke P. M. Hoevenaars, Arie G. Nieuwenhuizen, Evert M. van Schothorst · 2014 · Nutrients
- The Neuroendocrine Control of Energy BalanceRobert H. Lustig · 2010 · Springer eBooks
- Principles of Energy HomeostasisRexford S. Ahima · 2015 · Springer eBooks
- Metabolic Slowing Vanished 5 Years After Sleeve Gastrectomy in Patients With Obesity and Prediabetes/DiabetesSilvia Bettini, Gabriella Milan, Francesca Favaretto, Roberto Fabris, Chiara Dal Prà, Giulia Quinto, Chiara Cosma, Roberto Vettor, Luca Busetto · 2022 · The Journal of Clinical Endocrinology & Metabolism
- Angiotensin in the Arcuate: Mechanisms Integrating Cardiometabolic Control: The 2022 COH Mid-Career Award for Research ExcellenceSamuel B. R. Lawton, Valerie A. Wagner, Pablo Nakagawa, Jeffrey L. Segar, Curt D. Sigmund, Lisa Linda Morselli, Justin L. Grobe · 2024 · Hypertension
- Obesity and Thyroid FunctionGiovanni Ceccarini, Alessio Basolo, Ferruccio Santini · 2014 · Springer eBooks
- Adipokines and MetabolismRexford S. Ahima, Laura M. Scolaro, Hyeong-Kyu Park · 2016 · Springer eBooks
- Gestational weight gain by reduced brain melanocortin activity affects offspring energy balance in ratsA.C.M. Heinsbroek, Gertjan van Dijk · 2008 · International Journal of Obesity
- Characterizing the Homeostatic and Hedonic Markers of the Susceptible PhenotypeJohn Edward Blundell, Eleanor Jane Bryant, Clare Louise Lawton, Jason C. G. Halford, Erik B. Näslund, Graham Finlayson, Neil A. King · 2010 · Elsevier eBooks
- Doctor-patient interactions during medical consultations about obesity.Helena Webb · 2009 · Nottingham ePrints (University of Nottingham)
- Long-Term Hormonal Adaptations to Weight LossFernando Cordido, Susana Sangiao‐Alvarellos, Miguel Pérez Fontán · 2012 · New England Journal of Medicine
- Reduced contextually induced muscle thermogenesis in rats with calorie restriction and lower aerobic fitness but not monogenic obesityAshley Shemery, Meredith Zendlo, Jesse Kowalski, Erin Gorrell, Scott Everett, Jacob G. Wagner, Ashley E. Davis, Lauren G. Koch, Steven L. Britton, Joram D. Mul et al. · 2023 · Temperature
- Weight History Correlates of Resting Energy Expenditure in Women With Bulimia NervosaSimar Singh, Laurel Mayer, MICHAEL S. ROSENBAUM, Michael R. Lowe · 2024 · International Journal of Eating Disorders
- Impact of peripheral thyroid hormone balance on liver fat: insights from the NutriAct trialMiriam Sommer, Thu-Huong Nguyen, Laura Pletsch‐Borba, Charlotte Wernicke, Frank Tacke, Tanja Schwerdtle, Denny Pellowski, Jürgen Machann, Joachim Spranger, Eva Katrin Wirth et al. · 2024 · European Journal of Endocrinology
- Gut hormones of preterm infants with abdominal symptoms and hypothyroxinemiaRyou Kawamata, Yume Suzuki, Yukari Yada, Yasunori Koike, Yumi Kono, Naoto Takahashi · 2014 · Pediatrics International
- Adaptive Responses to Weight LossMICHAEL S. ROSENBAUM, Rudolph L. Leibel · 2014 · Springer eBooks
- Carbohydrate, Fat and Protein Metabolism in ObesityJosé Eduardo Galgani, Víctor Cortés, Fernando Carrasco N · 2015 · Springer eBooks
- Gene environment Interactions and the Origin of the Modern Obesity EpidemicJohn Roger Speakman · 2007 · Elsevier eBooks
- Can muscle avert GLP1R weight plateau and regain?Dongdong Wang, Andre Djalalvandi, Christina T. Saed, Katherine Mary Morrison, Gregory R. Steinberg · 2025 · Cell Reports Medicine
- The important role of comorbidities in the management of obesitySarah R. Barenbaum, Beverly G. Tchang, Louis J. Aronne · 2026 · Journal of the Endocrine Society
- Bariatric Surgery in the Era of GLP1RA: A Narrative ReviewMathula Muhundan, Satya Dash · 2026 · Advances in Therapy
- Leptin Interaction with Brain Orexigenic and Anorexigenic PathwaysDenis G. Baskin · 2014 · Springer eBooks
- Central leptin signaling transmits positive valenceAmber L. Alhadeff, Sineadh M. Conway, Zhi Yi Ong, Hallie S. Wald, Mitchell F. Roitman, Harvey J. Grill · 2019 · Brain Research
- Reversible insulin resistance helps Bactrian camels survive fastingFucheng Guo, Rendalai Si, Quanyun Li, Le Hai, Li Yi, Jing He, Liang Ming, Rimutu Ji · 2021 · Scientific Reports
- Does selective leptin resistance cause obesity-related hypertension?Marcelo Correia, William Geoffrey Haynes · 2008
- Anorexia Nervosa and Bulimia NervosaGilberto Paz-Filho, Júlio Licinio · 2009 · Elsevier eBooks
- Translational and Post-translational Control of Leptin Production by Fat CellsKonstantin V. Kandror · 2015 · Springer eBooks
- Developmental Origins of ObesityFrank B. Hu · 2008 · Oxford University Press eBooks
- Leptin, appetite and weight rebound in overweight/obesity individuals undertook weight loss program using a low calorie diet with or without exerciseHarry Freitag Luglio Muhammad, Dian Caturini Sulistyoningrum, Ika Riski Muharomin, Emy Huriyati · 2017 · Mediterranean Journal of Nutrition and Metabolism
- Effects of birth weight and dietary fat on intake, body composition, and plasma thyroxine in neonatal lambsJose M Ramos-Nieves, Sarah L. Giesy, Molly Mae McGuckin, Yves R. Boisclair · 2020 · Journal of Animal Science
- Nutraceutical meal replacements: more effective than all-food diets in the treatment of obesityWendy M Miller, Katherine E. Nori Janosz, Kerstyn C. Zalesin, Peter Andrew McCullough · 2007 · Therapy
- UCP2, SHBG, Leptin, and T3 Levels are Associated with Resting Energy Expenditure in Obese WomenSomaye Ahmadi, Hamideh Pishva, Mohammad Reza Eshraghian, Mehdi Hedayati · 2019 · Endocrine Metabolic & Immune Disorders - Drug Targets
- Intensive Therapies for the Treatment of Pediatric ObesityJoan C. Han, Jack Adam Yanovski · 2008 · Issues in clinical child psychology
- Leptin, the sympathetic nervous system and blood pressureGuido M. Grassi · 2014 · Journal of Hypertension
- Trends in obesity and type 2 diabetes : ethnic aspects and links to adipokinesMikael Lilja · 2011 · DiVA at Umeå University (Umeå University)
- Approach to the Patient: Clinical Outcomes and Interim Strategies Following Discontinuation of Incretin AgonistsSarah R. Barenbaum, Mohini Aras, Sangeeta Rao Kashyap, Louis J. Aronne · 2025 · The Journal of Clinical Endocrinology & Metabolism
- Overnutrition in mice impairs thyroid hormone biosynthesis and utilization, causing hypothyroidism, despite remarkable thyroidal adaptationsJessica Rampy, Alejandra Paola Torres-Manzo, Kendra Hoffsmith, Matthew A. Loberg, Quanhu Sheng, Federico Salas-Lucia, Antonio C. Bianco, Rafael Arrojo e Drigo, Huiying Wang, Vivian Lee Weiss et al. · 2026 · Journal of Clinical Investigation
- Obesity: Nature or Nurture?Robert H. Lustig · 2010 · Endocrine updates
- LeptinMalaka B. Jackson, Rexford S. Ahima · 2007 · Humana Press eBooks
- The Physiological Regulation of Body Fat MassPriya Sumithran · 2023 · Gastroenterology Clinics of North America
- Strategies for Long-Term Weight Loss and MaintenanceYoo Bin Seo · 2023 · Korean Journal of Family Practice
- Principles of Energy HomeostasisRexford S. Ahima · 2023 · Springer eBooks
- Computational Modelling of Energy Metabolism and Body Composition DynamicsKevin D. Hall · 2014 · Springer eBooks
- Obesity and Weight Loss: The Influence of Thyroid Hormone on AdipokinesRenata de Azevedo Melo Luvizotto, Sandro Jos, Miriane de, Maria Teresa De Síbio, Keize Nagamati, Clia Regina · 2012 · InTech eBooks
- Calorie restriction-mediated restoration of hypothalamic signal transducer and activator of transcription 3 (STAT3) phosphorylation is not effective for lowering the body weight set point in IRS-2 knockout obese miceSatoko Senda, Atsushi Inoue, Arshad Mahmood, Ryo Suzuki, Nozomu Kamei, Naoto Kubota, Taku Watanabe, Masashi Aoyama, Allah Nawaz, Yoshiaki Ohkuma et al. · 2015 · Diabetology International
- Energy Expenditure in ObesityLeanne Maree Redman, Éric Ravussin · 2007 · Humana Press eBooks
- Leptin ResistanceYong‐Woon Kim · 2007 · Journal of Korean Endocrine Society
- Carbohydrate, Fat, and Protein Metabolism in ObesityJosé Eduardo Galgani, Víctor Cortés, Fernando Carrasco N · 2016 · Springer eBooks
- The Association of Leptin Levels in Iraqi Women with Newly Diagnosed Thyroid DysfunctionHaider Ridha Mohammed Saeed, Sura Ahmed Abdulsattar, Abdilkarim Y. Al-Samarriae · 2023 · The Egyptian Journal of Hospital Medicine
- Weight Management in Diabetes PreventionXavier Pi-Sunyer · 2007 · Humana Press eBooks
- Adipokines and MetabolismRexford S. Ahima, Laura M. Scolaro, Hyeong-Kyu Park · 2015 · Springer eBooks
- Pharmacologic Therapy For ObesityLorenna Rodrigues Silva Sombra, Catherine Anastasopoulou · 2021 · StatPearls
- Principles of Energy HomeostasisRexford S. Ahima · 2016 · Springer eBooks
- Tirzepatide Synergizes with Leptin on Weight Loss and Restoring Metabolic Homeostasis in Diet-induced Obesity ModelXun Sun, Yuexi Yin, Min Song, Brian A. Droz, YANZHU LIN, Kristen N Beaty, Baohua Zhou, Hyun Cheol Roh, Jonathan Matthew Wilson, Paul Cain et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- High-Amylose Maize Resistant Starch Type 2 (HAM-RS2) Intake, Body Composition, and Satiety in Overweight AdultsMindy A. Patterson · 2014
- The interaction of diet-induced obesity and chronic stress in a mouse model of menopauseNadja Knox, Ali Yasrebi, Daniel Caramico, Katherine A. Denney, Kimberly Wiersielis, Benjamin Adam Samuels, Troy Adam Roepke · 2026 · Hormones and Behavior
- Exploring the disconnect: mechanisms underpinning the absence of physical function improvement with SGLT2 inhibitorsCian Sutcliffe, Jack Alistair Sargeant, Thomas E. Yates, Melanie Jane Davies, Luke A. Baker · 2025 · Frontiers in Systems Biology
- Evaluation of leptin treatment on maintenance of body weight loss in diet‐induced obese miceDanna M. Breen, Rocío del M. Saavedra-Peña, Stephanie Joaquim, Jimmy Kong, Ryan Reese, J. Brent Kuzmiski, John C. Stansfield, Rhys Jones, Kendra K. Bence, V. Margaret Jackson · 2025 · Diabetes Obesity and Metabolism
- Adaptive Ketogenic–Mediterranean Protocol (AKMP) in Real Clinical Practice: 14-Week Pre–Post Cohort Study on Glucolipid Markers and SafetyCayetano García-Gorrita, Nadia San Onofre, Juan Francisco Merino-Torres, José Miguel Soriano · 2025 · Nutrients
- Obesogenic effects of warm temperature involve feeding adaptation by preoptic area leptin receptor neuronsLee D. Kaiser, Nathan Lee, Katelynn Zaunbrecher, Clint E. Kinney, Jaclyn Williams, Michael F. Smith, Robert C. Noland, Sangho Yu, Christopher D. Morrison, Hans‐Rudolf Berthoud et al. · 2026 · Communications Biology
- Improvement of Leptin ResistanceYong Woon Kim · 2013 · Journal of Yeungnam Medical Science
- Role of Thyrotropin-Releasing Hormone in the Regulation of the Thyroid AxisAnthony Neil Hollenberg · 2009 · Elsevier eBooks
- Genetically determined lean mass and dietary responseSatya Dash, Andrew D. Paterson · 2020 · Diabetes Obesity and Metabolism
- Principles of Energy HomeostasisRexford S. Ahima · 2023 · Springer eBooks
- Longitudinal estimates of resting energy expenditure using predictive equations in individuals with excess weight after weight loss: A systematic review with meta-analysisMateus de Lima Macêna, Déborah Tenório da Costa Paula, André Eduardo da Silva Júnior, Dafiny Rodrigues Silva Praxedes, Nassib Bezerra Bueno · 2023 · Clinical Nutrition ESPEN
- Approaches to teaching about mechanisms of obesity in undergraduate pathophysiology coursesKristen L. W. Walton · 2024 · AJP Advances in Physiology Education
- Neuroendocrine and Metabolic Adaptations in the Central Nervous System That Facilitate Weight RegainRonald M. Lechan, Csaba Fekete · 2010 · Springer eBooks
- Conceptos tradicionales y emergentes sobre el balance energéticoErwin Chiquete, Paulina Tolosa · 2013 · Revista de Endocrinología y Nutrición
- The cultural and medical determination of the obesityRadojica V. Stolic · 2015 · Praxis medica
- LEPTIN RESISTANCE AND TYPE 2 DIABETESOleksandra Oleshchuk, Г. Я. Лой · 2017 · International Journal of Medicine and Medical Research
- The Role of Leptin in Body Weight RegulationAlicja A. Skowronski · 2017