HIF2α cooperates with RAS to promote lung tumorigenesis in mice
Kim, William Y., Perera, Samanthi, Zhou, Bing, Carretero, Julian, Yeh, Jen Jen, Heathcote, Samuel A., Jackson, Autumn L., Nikolinakos, Petros, Ospina, Beatriz, Naumov, George, Brandstetter, Kathleyn A., Weigman, Victor J., Zaghlul, Sara, Hayes, D. Neil, Padera, Robert F., Heymach, John V., Kung, Andrew L., Sharpless, Norman E., Kaelin, William G., Wong, Kwok-Kin·2009·Journal of Clinical Investigation
DOI 10.1172/jci38443
Cited by (141)
Items 101–141 of 141
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- Proteomic Alterations in Response to Hypoxia Inducible Factor 2α in Normoxic Neuroblastoma CellsFlora Cimmino, Lucia Pezone, Marianna Avitabile, Luca Persano, Monica Vitale, Mauro Sassi, Silvia Bresolin, Valentina Serafin, Nicola Zambrano, Andrea Scaloni et al. · 2016 · Journal of Proteome Research
- Correlation of HIF-1α/HIF-2α expression with FDG uptake in lung adenocarcinomaKotaro Higashi, Toshiaki Yamagishi, Yoshimichi Ueda, Yasuhito Ishigaki, Miyako Shimasaki, Yuka Nakamura, Manabu Oguchi, Tsutomu Takegami, Motoyasu Sagawa, Hisao Tonami · 2016 · Annals of Nuclear Medicine
- Acute Hypoxia Stress-Induced Apoptosis in Gill of Japanese Flounder (Paralichthys olivaceus) by Modulating the Epas1/Bad PathwayGuangling Li, Binghua Liu, Jun Yang, Xiaohui Li, Hao Wang, Haishen Wen, Feng He · 2022 · Biology
- Endothelial PAS domain protein 1 gene hypomethylation is associated with colorectal cancer in Han ChineseRanran Pan, Cong Zhou, Jie Dai, Xiuru Ying, Hang Yu, Jie Ming Zhong, Yihan Zhang, Boyi Wu, Yiyi Mao, Dongping Wu et al. · 2018 · Experimental and Therapeutic Medicine
- The Biology of HIFα Proteins in Cell Differentiation and DiseaseInmaculada Royo González, Victoria Moreno‐Manzano, Francisco Javier Rodríguez-Jiménez, Pilar Sepúlveda, José-María Sánchez-Puelles · 2011 · Vitamins and hormones
- Temporal Dissection of K-rasG12D Mutant In Vitro and In Vivo Using a Regulatable K-rasG12D Mouse AlleleZuoyun Wang, Yan Feng, Nabeel Bardessy, Kwok‐Kin Wong, Xinyuan Liu, Hongbin Ji · 2012 · PLoS ONE
- GABARAPL1 is essential in extracellular vesicle cargo loading and metastasis developmentJoël E.J. Beaumont, Jinzhe Ju, Lydie M.O. Barbeau, Imke Demers, Kim G.M. Savelkouls, Kasper Derks, Freek G. Bouwman, Marca H. M. Wauben, Marijke I. Zonneveld, Tom G. Keulers et al. · 2023 · Radiotherapy and Oncology
- Tumour Hypoxia and the Hypoxia-Inducible Transcription Factors: Key Players in Cancer Progression and MetastasisAnnika Jögi · 2015 · Springer eBooks
- Antiangiogenic Action of JZL184 on Endothelial Cells via Inhibition of VEGF Expression in Hypoxic Lung Cancer CellsFelix Wittig, Liza Pannenberg, Rico Schwarz, Sander Bekeschus, Robert Ramer, Burkhard Hinz · 2023 · Cells
- Homology modeling and molecular dynamics simulation of the HIF2α degradation-related HIF2α-VHL complexXiaotian Dong, Xiaoru Su, Jiong Yu, Jingqi Liu, Xiaowei Shi, Qiaoling Pan, Jinfeng Yang, Jiajia Chen, Lanjuan Li, Hongcui Cao · 2016 · Journal of Molecular Graphics and Modelling
- Bone marrow overexpression of SNAI1 is an early indicator of intrinsic drug resistance in patients with de novo acute myeloid leukemiaMahmoud B. Y. Gouda, Naglaa Mostafa Hassan, Eman Kandil · 2022 · The Journal of Gene Medicine
- HIF2α-dependent Dock4/Rac1-signaling regulates formation of adherens junctions and cell polarity in normoxiaIrina B. Raykhel, Veli‐Pekka Ronkainen, Johanna Myllyharju, Aki Manninen · 2024 · Scientific Reports
- Inflammation and Lung Cancer: The Role of Epithelial–Mesenchymal TransitionTonya C. Walser, Stacy J. Park, Jane Yanagawa, Steven M. Dubinett · 2015 · Springer eBooks
- INT6 / eIF3e represses E‐cadherin expression through HIF2α in lung carcinoma A549 cellsSaki Gotoh-Saito, Daichi Sadato, Futoshi Shibasaki · 2022 · Genes to Cells
- Hypoxia-inducible factor-2α (HIF-2α) mediates the effects of hypoxia on the promotion of HeLa cell viability, colony formation, and invasion capacity in vitroJ. Xiong, F.F. Zhu, Miao Nie · 2015 · Genetics and Molecular Research
- HIF2α negatively regulates MYCN protein levels and promotes a low-risk noradrenergic phenotype in neuroblastomaJuan Yuan, Subhamita Maitra, Eirini Antoniou, Jiacheng Zhu, Wenyu Li, Ilknur Safak Demirel, Kostantinos Toskas, Iria Laura Martinez, Lacin Ozcimen, Henrik Lindehell et al. · 2025 · Proceedings of the National Academy of Sciences
- Normoxic HIFα-mediated metabolic rewiring in cancer as a novel therapeutic target of tumor heterogeneityAnaís Sánchez‐Castillo, Jairo G. E. Lommen, Denise Consten, Kim G.M. Savelkouls, Lydie M.O. Barbeau, Kasper M. A. Rouschop, Marc Vooijs, Kim Rosalie Kampen · 2026 · Cancer & Metabolism
- Association of COPD and Lung Cancer: How Does COPD Management Change the Outcome of Treatment of Lung Cancer?Shinsaku Togo, Yukiko Namba, Kazuhisa Takahashi · 2016 · Respiratory disease series
- Exploration Into the Effects of Hypoxia in an In Vitro Canine Glioblastoma ModelJennifer Koehler · 2013
- Hypoxic Adaptation and Arsenic Trioxide Treatment in Small Cell Lung CarcinomaMatilda Munksgaard Thorén · 2013 · Lund University Publications (Lund University)
- Chemokine Regulation of Cell Trafficking in Lung Cancer MetastasisLeena Gandhi, Kwok‐Kin Wong · 2012 · Open Journal of Hematology
- In Vitro Hypoxic Preconditioning of Bone Marrow Stromal Cells Triggers ERK-Mediated Signaling and Growth of L363 Myeloma Cells Celulele stromale ale mduvei hematopoietice precondiionate la hipoxie in vitro induc proliferarea celulelor mielomatoase L363 i semnalizarea intracelularERK-mediatGeorgiana Emilia Grigore, Mihaela Zlei, Dragos Peptanariu, Iuliu Cristian Ivanov, Didona Anca Ungureanu, Eugen Carasevici · 2011
- Inflammation and Lung Cancer: PreventionAlison K. Bauer, York E. Miller, Robert L. Keith · 2015 · Springer eBooks
- A regulation probability model-based meta-analysis of multiple transcriptomics data sets for cancer biomarker identificationXin-Ping Xie, Yufeng Xie, Hongqiang Wang · 2017 · BMC Bioinformatics
- Impact of hypoxia on hepatitis B virus replicationNicholas Ross Frampton · 2018 · University of Birmingham Institutional Research Archive (University of Birmingham)
- Inhibition of compensatory survival and proliferative pathway activation induced by mTOR inhibition in renal cell carcinomaSean T. Bailey · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
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- Caractérisation de l'effet cytoprotecteur des cellules souches mésenchymateuses sur l'apoptose et sur les altérations phénotypiques des cellules épithèliales alvéolaires soumises à l'hypoxieOlivier Bernard · 2016 · theses.fr (ABES)