Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

Kume, Shinji, Uzu, Takashi, Horiike, Kihachiro, Chin-Kanasaki, Masami, Isshiki, Keiji, Araki, Shin-ichi, Sugimoto, Toshiro, Haneda, Masakazu +2 more·2010·Journal of Clinical Investigation

DOI 10.1172/jci41376

Cited by (639)

Items 101–200 of 639

Mechanisms and disease implications of sirtuin-mediated autophagic regulation
In Hye Lee · 2019 · Experimental & Molecular Medicine
Role of melatonin in the regulation of autophagy and mitophagy: A review
Ana M. Coto‐Montes, José Antonio Boga, Sergio Rosales‐Corral, Lorena Fuentes‐Broto, Dun‐Xian Tan, Russel Joseph Reiter · 2012 · Molecular and Cellular Endocrinology
Cellular senescence and autophagy in the pathogenesis of chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF)
Kazuyoshi Kuwano, Jun Araya, Hiromichi Hara, Shunsuke Minagawa, Naoki Takasaka, Saburo Ito, Kenji Kobayashi, Katsutoshi Nakayama · 2016 · Respiratory Investigation
Alteration of Forkhead Box O (Foxo4) Acetylation Mediates Apoptosis of Podocytes in Diabetes Mellitus
Peter Y. Chuang, Yan Dai, Ruijie Liu, Helen He, Matthias Kretzler, Belinda Jim, Clemens David Cohen, Cijiang He · 2011 · PLoS ONE
Aging and Chronic Kidney Disease
Kosaku Nitta, Kazuyoshi Okada, Mitsuru Yanai, SUSUMU Y. TAKAHASHI · 2013 · Kidney & Blood Pressure Research
SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells
Tetsuro Koyama, Shinji Kume, Daisuke Koya, Shin‐ichi Araki, Keiji Isshiki, Masami Chin‒Kanasaki, Toshiro Sugimoto, Masakazu Haneda, Takeshi Sugaya, Atsunori Kashiwagi et al. · 2011 · Free Radical Biology and Medicine
Sirtuins and Insulin Resistance
Shuang Zhou, Xiaoqiang Tang, Hou‐Zao Chen · 2018 · Frontiers in Endocrinology
Sirtuin and metabolic kidney disease
Shu Wakino, Kazuhiro Hasegawa, Hiroshi Itoh · 2015 · Kidney International
A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 1.
Gregory S. Kelly · 2010 · PubMed
Disease drivers of aging
Hodes, Richard J., Sierra, Felipe, Austad, Steven N., Epel, Elissa, Neigh, Gretchen N., Erlandson, Kristine M., Schafer, Marissa J., LeBrasseur, Nathan K., Wiley, Christopher, Campisi, Judith et al. · 2016 · Annals of the New York Academy of Sciences
Role of sirtuin-1 in diabetic nephropathy
Wanning Wang, Weixia Sun, Yanli Cheng, Zhonggao Xu, Lu Cai · 2019 · Journal of Molecular Medicine
Interplay of skeletal muscle and adipose tissue: sarcopenic obesity.
Minjeong Park, Kyung Mook Choi · 2023 · Metabolism: Clinical and Experimental
HIF-1-driven skeletal muscle adaptations to chronic hypoxia: molecular insights into muscle physiology
F. B. Favier, Florian Alexis Britto, Damien Gilles Freyssenet, Xavier A. Bigard, H. Benoit · 2015 · Cellular and Molecular Life Sciences
Exercise activates lysosomal function in the brain through AMPK‐SIRT1‐TFEB pathway
Jun Huang, Xue Wang, Yi Zhu, Zhe Li, Yu‐Ting Zhu, Junchao Wu, Zheng‐Hong Qin, Min Xiang, Fang Lin · 2019 · CNS Neuroscience & Therapeutics
Pathways for Ischemic Cytoprotection: Role of Sirtuins in Caloric Restriction, Resveratrol, and Ischemic Preconditioning
Kahlilia C. Morris, Hung Wen Lin, John W. Thompson, Miguel A. Pérez‐Pinzón · 2011 · Journal of Cerebral Blood Flow & Metabolism
Sirt1–hypoxia‐inducible factor‐1α interaction is a key mediator of tubulointerstitial damage in the aged kidney
Dong‐Ryeol Ryu, Mi Ra Yu, Kyoung Hye Kong, Hyoungnae Kim, Soon‐Hyo Kwon, Jin Seok Jeon, Dong Cheol Han, Hyunjin Noh · 2019 · Aging Cell
Role of Impaired Nutrient and Oxygen Deprivation Signaling and Deficient Autophagic Flux in Diabetic CKD Development: Implications for Understanding the Effects of Sodium-Glucose Cotransporter 2-Inhibitors
Milton Packer · 2020 · Journal of the American Society of Nephrology
Sirt1 regulates acrosome biogenesis by modulating autophagic flux during spermiogenesis in mice
Chao Liu, Zhenhua Song, Lina Wang, Haiyan Yu, Weixiao Liu, Yongliang Shang, Zhiliang Xu, Haichao Zhao, Fengyi Gao, Jiamin Wen et al. · 2016 · Development
Microglia activation and phagocytosis: relationship with aging and cognitive impairment in the rhesus monkey
Eli Shobin, Michael P. Bowley, Larissa Isabel Estrada, Nadine C. Heyworth, Mary E. Orczykowski, Sherri A. Eldridge, Samantha M. Calderazzo, Farzad Mortazavi, Tara L. Moore, Douglas L. Rosene · 2017 · GeroScience
TAp63 Is a Master Transcriptional Regulator of Lipid and Glucose Metabolism
Xiaohua Su, Young Jin Gi, Deepavali Chakravarti, Io Long Chan, Aijun Zhang, Xuefeng Xia, Kenneth Yee Tsai, Elsa Renee Flores · 2012 · Cell Metabolism
Mitochondria, the NLRP3 Inflammasome, and Sirtuins in Type 2 Diabetes: New Therapeutic TargetsReviewing Editors: Markus Bachschmid, Dylan Burger, Vittorio Calabrese, Amadou Camara, Lukas Kubala, Giuseppe Poli, and Chandan K. Sen
Susana Rovira‐Llopis, Nadezda Apostolova, Celia Bañuls, Jordi Muntané, Milagros Rocha, Víctor M. Víctor · 2017 · Antioxidants and Redox Signaling
Mitochondrial Biogenesis in Kidney Disease
Joel M. Weinberg · 2011 · Journal of the American Society of Nephrology
Prolonged fasting suppresses mitochondrial NLRP3 inflammasome assembly and activation via SIRT3-mediated activation of superoxide dismutase 2
Javier Traba, Sarah S. Geiger, Miriam A. Osei, Kim Han, One Hyuk Ra, Richard M. Siegel, David R. Gius, Michael N. Sack · 2017 · Journal of Biological Chemistry
β-Cell Autophagy in Diabetes Pathogenesis
Michelle R. Marasco, Amelia K. Linnemann · 2018 · Endocrinology
The Effects of Calorie Restriction on Autophagy: Role on Aging Intervention
Ki Wung Chung, Hae Young Chung · 2019 · Nutrients
Mitochondrial Biogenesis in Health and Disease. Molecular and Therapeutic Approaches
Fabián Sanchis‐Gomar, Jose Luis García‐Giménez, Mari Carmen Gómez‐Cabrera, Federico Vicente Pallardó · 2014 · Current Pharmaceutical Design
Autophagy in vascular endothelial cells
Fan Jiang · 2016 · Clinical and Experimental Pharmacology and Physiology
Manganese Superoxide Dismutase Dysfunction and the Pathogenesis of Kidney Disease
Munehiro Kitada, Jing Xu, Yoshio Ogura, Itaru Monno, Daisuke Koya · 2020 · Frontiers in Physiology
SIRT1-FOXOs activity regulates diabetic complications
Manjiri P. Jalgaonkar, Urvi M. Parmar, Yogesh Anant Kulkarni, Manisha J. Oza · 2021 · Pharmacological Research
Polyphenols as Caloric Restriction Mimetics Regulating Mitochondrial Biogenesis and Mitophagy
Davinelli, Sergio, De Stefani, Diego, De Vivo, Immaculata, Scapagnini, Giovanni · 2020 · Trends in Endocrinology & Metabolism
METTL14 aggravates podocyte injury and glomerulopathy progression through N6-methyladenosine-dependent downregulating of Sirt1
Zhihui Lu, Hong Liu, Nana Song, Yiran Liang, Jiaming Zhu, Jing Chen, Yichun Ning, Jiachang Hu, Yi Fang, Jie Teng et al. · 2021 · Cell Death and Disease
Autophagy: A Novel Therapeutic Target for Diabetic Nephropathy
Shinji Kume, Daisuke Koya · 2015 · Diabetes & Metabolism Journal
The mitochondrial-targeted peptide, SS-31, improves glomerular architecture in mice of advanced age
Mariya T. Sweetwyne, Jeffrey W. Pippin, Diana G. Eng, Kelly L. Hudkins, Ying Ann Chiao, Matthew D. Campbell, David Joseph Marcinek, Charles E. Alpers, Hazel H. Szeto, Peter S. Rabinovitch et al. · 2017 · Kidney International
Resveratrol serves as a protein-substrate interaction stabilizer in human SIRT1 activation
Xuben Hou, David W. Rooklin, Hao Fang, Yingkai Zhang · 2016 · Scientific Reports
Autophagy Function and Regulation in Kidney Disease
Gur P. Kaushal, Kiran Chandrashekar, Luis Augusto Juncos, Sudhir V. Shah · 2020 · Biomolecules
Autophagy as a Therapeutic Target in Diabetic Nephropathy
Yuki Tanaka, Shinji Kume, Munehiro Kitada, Keizo Kanasaki, Takashi Uzu, Hiroshi Maegawa, Daisuke Koya · 2011 · Experimental Diabetes Research
Impact of neural stem cell-derived extracellular vesicles on mitochondrial dysfunction, sirtuin 1 level, and synaptic deficits in Alzheimer’s disease
Li, Bo, Liu, Jianhui, Gu, Guojun, Han, Xu, Zhang, Qi, Zhang, Wei · 2020 · Journal of Neurochemistry
SGLT2 Inhibitors as Calorie Restriction Mimetics: Insights on Longevity Pathways and Age-Related Diseases
Caroline Wei Shan Hoong, Marvin Wei Jie Chua · 2021 · Endocrinology
Intercellular Transfer of Microvesicles from Young Mesenchymal Stromal Cells Rejuvenates Aged Murine Hematopoietic Stem Cells
Rohan SUDHIR Kulkarni, Manmohan S. Bajaj, Suprita S. Ghode, Sapana S. Jalnapurkar, Lalita S. Limaye, Vaijayanti Prakash Kale · 2017 · Stem Cells
Mitochondrial Activity and Dynamics Changes Regarding Metabolism in Ageing and Obesity
López-Lluch, Guillermo · 2017 · Mechanisms of Ageing and Development
Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity
Jae‐Kyo Jeong, Myung‐Hee Moon, You-Jin Lee, Jae‐Won Seol, Sang‐Youel Park · 2012 · Neurobiology of Aging
Nutrient Sensing and the Oxidative Stress Response
Hanzhi Luo, Hou-Hsien Chiang, Makensie Louw, Albert Susanto, Danica Chen · 2017 · Trends in Endocrinology and Metabolism
Regulating Autophagy as a Therapeutic Target for Diabetic Nephropathy
Munehiro Kitada, Yoshio Ogura, Itaru Monno, Daisuke Koya · 2017 · Current Diabetes Reports
Longevity Pathways (mTOR, SIRT, Insulin/IGF-1) as Key Modulatory Targets on Aging and Neurodegeneration
Caio Henrique Mazucanti, João Victor Cabral‐Costa, Andréa Rodrigues Vasconcelos, Diana Zukas Andreotti, Cristóforo Scavone, Elisa Mitiko Kawamoto · 2015 · Current Topics in Medicinal Chemistry
Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay
Fiorentino, Loredana, Cavalera, Michele, Menini, Stefano, Marchetti, Valentina, Mavilio, Maria, Fabrizi, Marta, Conserva, Francesca, Casagrande, Viviana, Menghini, Rossella, Pontrelli, Paola et al. · 2013 · EMBO Molecular Medicine
Mechanisms and biological functions of autophagy in diseased and ageing kidneys
Sophie Fougeray, Nicolas Pallet · 2014 · Nature Reviews Nephrology
Renal Allograft Fibrosis: Biology and Therapeutic Targets
Peter Boor, Jürgen Floege · 2015 · American Journal of Transplantation
Autophagy in Kidney Health and Disease
Zhibo Wang, Mary E. Choi · 2013 · Antioxidants and Redox Signaling
Suppression of Autophagy During Liver Regeneration Impairs Energy Charge and Hepatocyte Senescence in Mice
Takeo Toshima, Ken Shirabe, Takasuke Fukuhara, Toru Ikegami, Tomoharu Yoshizumi, Yuji Soejima, Tetsuo Ikeda, Shinji Okano, Yoshihiko Maehara · 2014 · Hepatology
Reduction in podocyte SIRT1 accelerates kidney injury in aging mice
Chuang, Peter Y., Cai, Weijing, Li, Xuezhu, Fang, Lu, Xu, Jin, Yacoub, Rabi, He, John Cijiang, Lee, Kyung · 2017 · American Journal of Physiology-Renal Physiology
A very-low-protein diet ameliorates advanced diabetic nephropathy through autophagy induction by suppression of the mTORC1 pathway in Wistar fatty rats, an animal model of type 2 diabetes and obesity
Kitada, Munehiro, Ogura, Yoshio, Suzuki, Taeko, Sen, Shi, Lee, Seon Myeong, Kanasaki, Keizo, Kume, Shinji, Koya, Daisuke · 2016 · Diabetologia
Pro-autophagic polyphenols reduce the acetylation of cytoplasmic proteins
Federico Pietrocola, Guillermo Mariño, Delphine Lissa, Erika Vacchelli, Shoaib Ahmad Malik, Mireia Niso‐Santano, Naoufal Zamzami, Lorenzo Galluzzi, Maria Chiara Maiuri, Guido Kroemer · 2012 · Cell Cycle
Quercetin Suppresses Apoptosis and Attenuates Intervertebral Disc Degeneration via the SIRT1-Autophagy Pathway
Dong Wang, Xin He, Di Wang, Pandi Peng, Xiaolong Xu, Bo Gao, Chao Zheng, Han Wang, Haoruo Jia, Qiliang Shang et al. · 2020 · Frontiers in Cell and Developmental Biology
Sirt1 is essential for resveratrol enhancement of hypoxia-induced autophagy in the type 2 diabetic nephropathy rat
Liqun Ma, Rongguo Fu, Zhaoyang Duan, Jiamei Lu, Jie Gao, Lifang Tian, Zhian Lv, Chen Zhao, Jin Soo Han, Lining Jia et al. · 2016 · Pathology - Research and Practice
Control of Inflammation by Calorie Restriction Mimetics: On the Crossroad of Autophagy and Mitochondria
Enrique Gabandé‐Rodríguez, Manuel M. Gómez de las Heras, Marı́a Mittelbrunn · 2019 · Cells
Accelerated Kidney Aging in Diabetes Mellitus
Jing Guo, Huijuan Zheng, Wenting Zhang, Wenjiao Lou, Chen Xia, Xue Ting Han, Wei Jun Huang, Fan Zhang, Yaoxian Wang, Wei Jing Liu · 2020 · Oxidative Medicine and Cellular Longevity
SIRT1 Is a Potential Drug Target for Treatment of Diabetic Kidney Disease
Yifei Zhong, Kyung Lee, Cijiang He · 2018 · Frontiers in Endocrinology
SIRT1 inhibits chemoresistance and cancer stemness of gastric cancer by initiating an AMPK/FOXO3 positive feedback loop
Yifei An, Bo Wang, Xin Wang, Guoying Dong, Jihui Jia, Qing Yang · 2020 · Cell Death and Disease
Pre-emptive Short-term Nicotinamide Mononucleotide Treatment in a Mouse Model of Diabetic Nephropathy
Itaru Yasuda, Kazuhiro Hasegawa, Yusuke Sakamaki, Hirokazu Muraoka, Takahisa Kawaguchi, Ei Kusahana, Takashi Ono, Takeshi Kanda, Hirobumi Tokuyama, Shu Wakino et al. · 2021 · Journal of the American Society of Nephrology
The Role of SIRT1 in Diabetic Kidney Disease
Rabi Yacoub, Kyung Lee, Cijiang He · 2014 · Frontiers in Endocrinology
Autophagy and the kidney: health and disease
Yoshitsugu Takabatake, Tomonori Kimura, A. Takahashi, Yoshitaka Isaka · 2014 · Nephrology Dialysis Transplantation
Short-term calorie restriction protects against renal senescence of aged rats by increasing autophagic activity and reducing oxidative damage
Yichun Ning, Guangyan Cai, Li Zhuo, Jianjun Gao, Dan Feng Dong, Shaoyuan Cui, Zhe Feng, Suozhu Shi, Xueyuan Bai, Xuefeng Sun et al. · 2013 · Mechanisms of Ageing and Development
Fine Tuning Our Cellular Factories: Sirtuins in Mitochondrial Biology
Lei Zhong, Raúl Mostoslavsky · 2011 · Cell Metabolism
Autophagy and Tubular Cell Death in the Kidney
Andrea Havasi, Zheng Dong · 2016 · Seminars in Nephrology
BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy
Salwa Sebti, Christine Prébois, Esther Pérez-Gracia, Chantal Bauvy, Fabienne Desmots, Nelly Pirot, Céline Gongora, Anne-Sophie Bach, Andrew V. Hubberstey, Valérie Palissot et al. · 2014 · Proceedings of the National Academy of Sciences
Sirtuin1 and autophagy protect cells from fluoride-induced cell stress
M. Suzuki, John D. Bartlett · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue
Amiya Kumar Ghosh, Theresa Mau, Martin O’Brien, Sanjay Garg, Raymond L. Yung · 2016 · Aging
Pathological mechanisms of kidney disease in ageing
Takeshi Yamamoto, Yoshitaka Isaka · 2024 · Nature Reviews Nephrology
Mitochondrial longevity pathways
Anna Raffaello, Rosario Rizzuto · 2010 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
SIRT1 protects cochlear hair cell and delays age-related hearing loss via autophagy
Jiaqi Pang, Hao Xiong, Yongkang Ou, Haidi Yang, Yaodong Xu, Suijun Chen, Lan Lai, Yongyi Ye, Zhongwu Su, Hanqing Lin et al. · 2019 · Neurobiology of Aging
The Role of Autophagy in the Pathogenesis of Diabetic Nephropathy
Kosuke Yamahara, Mako Yasuda, Shinji Kume, Daisuke Koya, Hiroshi Maegawa, Takashi Uzu · 2013 · Journal of Diabetes Research
Liraglutide inhibits autophagy and apoptosis induced by high glucose through GLP-1R in renal tubular epithelial cells
Xueqin Zhao, G. Liu, H. Shen, Bin Gao, Xueyong Li, Jianfang Fu, Jinfeng Zhou, Qiuhe Ji · 2014 · International Journal of Molecular Medicine
Osteopontin induces autophagy to promote chemo-resistance in human hepatocellular carcinoma cells
Guoke Liu, Xiaoyu Fan, Min Tang, Rui Chen, Hao Wang, Rongjie Jia, Xuyu Zhou, Wei Jing, Huajing Wang, Yang� Yang et al. · 2016 · Cancer Letters
Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice
Takayoshi Sasako, Toshihiro Umehara, Kotaro Soeda, Kazuma Kaneko, Miho Suzuki, Naoki Kobayashi, Yukiko Okazaki, Miwa Tamura‐Nakano, Tomoki Chiba, Domenico Accili et al. · 2022 · Nature Communications
Hypoxia-Inducible Factor-1α: The Master Regulator of Endothelial Cell Senescence in Vascular Aging
Matilde Alique, Elsa Sánchez‐López, Guillermo Bodega, Chiara Giannarelli, Julia Carracedo, Rafael Ramı́rez · 2020 · Cells
Kidney aging—inevitable or preventable?
Devasmita Choudhury, Moshe Levi · 2011 · Nature Reviews Nephrology
Sirtuin 1: A Target for Kidney Diseases
Lili Kong, Hao Wu, Wenhua Zhou, Manyu Luo, Yi Tan, Lining Miao, Lu Cai · 2015 · Molecular Medicine
Organotypic hippocampal slice culture from the adult mouse brain: A versatile tool for translational neuropsychopharmacology
Hyunjeong Kim, Eosu Kim, Minsun Park, Eun Min Lee, Kee Namkoong · 2012 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
Mitochondrial Dysfunction in Age‐Related Metabolic Disorders
Venkateswaran Natarajan, Ritu Chawla, Tania Ken Lin Mah, Rajesh Vivekanandan, Shu Tan, Priscila Y. Sato, Karthik Babu Mallilankaraman · 2020 · PROTEOMICS
Oleate and eicosapentaenoic acid attenuate palmitate-induced inflammation and apoptosis in renal proximal tubular cell
Mariko Soumura, Shinji Kume, Keiji Isshiki, Naoko Takeda, Shin‐ichi Araki, Yuki Tanaka, Toshiro Sugimoto, Masami Chin‒Kanasaki, Yoshihiko Nishio, Masakazu Haneda et al. · 2010 · Biochemical and Biophysical Research Communications
Fibroblast autophagy in fibrotic disorders
Domenico Del Principe, Pasquale Lista, Walter Malorni, Anna Maria Giammarioli · 2012 · The Journal of Pathology
Autophagic deficiency is related to steroidogenic decline in aged rat Leydig cells
Wei-Ren Li, Liang Chen, Zhijie Chang, Xin Hua, Tao Liu, Yan-Quan Zhang, Guang-Yong Li, Feng Zhou, Yanqing Gong, Zhezhu Gao et al. · 2011 · Asian Journal of Andrology
Podocyte autophagic activity plays a protective role in renal injury and delays the progression of podocytopathies
Zeng, Caihong, Fan, Yun, Wu, Junnan, Shi, Shaolin, Chen, Zhaohong, Zhong, Yongzhong, Zhang, Changming, Zen, Ke, Liu, Zhihong · 2014 · The Journal of Pathology
Dual Regulation of Gluconeogenesis by Insulin and Glucose in the Proximal Tubules of the Kidney
Motohiro Sasaki, Takayoshi Sasako, Naoto Kubota, Yoshitaka Sakurai, Iseki Takamoto, Tetsuya Kubota, Reiko Inagi, George Seki, Moritaka Goto, Kohjiro Ueki et al. · 2017 · Diabetes
Formononetin attenuates kidney damage in type 2 diabetic rats
Manisha J. Oza, Yogesh Anant Kulkarni · 2019 · Life Sciences
Sirt1 inhibits renal tubular cell epithelial–mesenchymal transition through YY1 deacetylation in diabetic nephropathy
Lei Du, Xuan Qian, Yuan Li, Xizhi Li, Linlin He, Xu Liu, Yiqi Liu, Chengcheng Li, Pu Ma, Fanglin Shu et al. · 2020 · Acta Pharmacologica Sinica
Longevity genes, cardiac ageing, and the pathogenesis of cardiomyopathy: implications for understanding the effects of current and future treatments for heart failure
Milton Packer · 2020 · European Heart Journal
Autophagy in Aging and Alzheimer's Disease: Pathologic or Protective?
Aaron Barnett, Gregory J. Brewer · 2011 · Journal of Alzheimer s Disease
Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy
Bu-Hui Liu, Yue Tu, Weiming He, Yinglu Liu, Wei Wu, Qi‐Jun Fang, Haitao Tang, Renmao Tang, Zi-Yue Wan, Wei Sun et al. · 2018 · Aging
Aging and Renal Disease: Old Questions for New Challenges
Yu‐Hsiang Chou, Yung‐Ming Chen · 2021 · Aging and Disease
Ursolic Acid Attenuates Diabetic Mesangial Cell Injury through the Up-Regulation of Autophagy via miRNA-21/PTEN/Akt/mTOR Suppression
Xinxing Lu, Qiuling Fan, Xu Li, Li Lin, Yuan Yue, Yanyan Xu, Yan Ru Su, Dongcheng Zhang, Lining Wang · 2015 · PLoS ONE
SIRT4 overexpression protects against diabetic nephropathy by inhibiting podocyte apoptosis
Jianxia Shi, Qi-Jin Wang, Hui Li, Qin Huang · 2016 · Experimental and Therapeutic Medicine · Retracted
Age-related changes in the function of autophagy in rat kidneys
Cui, Jing, Bai, Xue-Yuan, Shi, Suozhu, Cui, Shaoyuan, Hong, Quan, Cai, Guangyan, Chen, Xiangmei · 2012 · AGE
Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes
Shiro Maeda, Daisuke Koya, Shin‐ichi Araki, Tetsuya Babazono, Tomoya Umezono, Masao Toyoda, Koichi Kawai, Masahito Imanishi, Takashi Uzu, Daisuke Suzuki et al. · 2011 · Clinical and Experimental Nephrology
Caloric restriction ameliorates kidney ischaemia/reperfusion injury through PGC‐1α–<scp>eNOS</scp> pathway and enhanced autophagy
Lempiäinen, J., Finckenberg, P., Mervaala, E. E., Sankari, S., Levijoki, J., Mervaala, E. M. · 2013 · Acta Physiologica
Cell Apoptosis and Autophagy in Renal Fibrosis
Xingchen Zhao, Man Jiang Livingston, Xinling Liang, Zheng Dong · 2019 · Advances in experimental medicine and biology
Apoptosis and autophagy in polycystic kidney disease (PKD)
Nowak, Kristen L., Edelstein, Charles L. · 2020 · Cellular Signalling
Target acquired: Selective autophagy in cardiometabolic disease
Trent D. Evans, Ismail Sergin, Xiangyu Zhang, Babak Razani · 2017 · Science Signaling
Inhibition of SIRT1/2 upregulates HSPA5 acetylation and induces pro-survival autophagy via ATF4-DDIT4-mTORC1 axis in human lung cancer cells
Ning Mu, Yuanjiu Lei, Yu Wang, Yingying Wang, Qinghui Duan, Guilin Ma, Xiangguo Liu, Ling Su · 2019 · APOPTOSIS
Puerarin Attenuates Diabetic Nephropathy by Promoting Autophagy in Podocytes
Xueling Li, Qingqing Zhu, Rong Zheng, Jiayi Yan, Minggang Wei, Yichen Fan, Yueyi Deng, Yifei Zhong · 2020 · Frontiers in Physiology