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Tardive Dyskinesia in Patients Treated with Major Neuroleptics: A Review of the Literature
Abstract
Since 1959 a growing number of reports have described a new type of neurological disorder in mental patients. This disorder, known as tardive dyskinesia, has been observed in approximately 500 cases but, judging from the accurate observations made by three separate groups of investigators, the syndrome is likely to be more frequent than one may suspect. Although manifestations of tardive dyskinesia occur in a number of diseases of the central nervous system, there is considerable evidence that the largescale use of phenothiazines or similar drugs in recent years is responsible for the great number of patients in mental hospitals exhibiting myoclonia and choreo-athetoid symptoms.
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Citations
Cited by
Tardive Dyskinesia: Prevalence and Risk Factors, 1959 to 1979
Kane, J. M. (1982) · Archives of General Psychiatry · doi:10.1001/archpsyc.1982.04290040069010 · Cited by 656
An experimental model of tardive dyskinesia
Klawans, H. L., & Rubovits, R. (1972) · Journal of Neural Transmission · doi:10.1007/bf01245320 · Cited by 275
Historical perspectives on tardive dyskinesia
Caroff, S. N., Ungvari, G. S., & Cunningham Owens, D. G. (2018) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2018.02.015 · Cited by 55
Metadata
- Authors
- CRANE, G. E.
- Venue
- American Journal of Psychiatry
- Published
- 1968-02
- Volume
- 124
- Issue
- 8S
- Pages
- 40-48
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2115674974
- Cited by
- 235
- References
- 0
- FWCI
- 24.62
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Tardive Dyskinesia in Patients Treated with Major Neuroleptics: A Review of the Literature. https://app.cochat.ai/papers/10.1176/ajp.124.8s.40
- The paper
- CRANE, G. E. (1968). Tardive Dyskinesia in Patients Treated with Major Neuroleptics: A Review of the Literature. American Journal of Psychiatry. https://doi.org/10.1176/ajp.124.8s.40
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
