The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Tardive dyskinesia: are first signs reversible?
Abstract
Although tardive dyskinesia, a serious and sometimes irreversible side effect of antipsychotic drug use, is becoming increasingly common, there is still considerable confusion concerning the course of the syndrome. The authors observed 12 psychiatric patients with tardive dyskinesia from the inception of the syndrome. They found that first symptoms rarely persisted if antipsychotics were discontinued and concluded that the length of time symptoms have persisted prior to drug discontinuation, not age at onset, may be the major variable determining reversibility of the syndrome.
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“There is likely to be considerable interindividual variability in this process, with patients able to tolerate greatly varying rates of reduction: given the data on time for TD to resolve, some long-term treated patients may need longer periods, and some first-episode patients or those treated for briefer periods may tolerate shorter tapering periods.75,76,78,101”
From A Method for Tapering Antipsychotic Treatment That May Minimize the Risk of Relapse (2021) · cites this paper as [101]
Citations
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“throughout the course of TD (Quitkin et al. 1977).”
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“In a series of 12 psychiatric patients, 24 – 62 years old, tardive dyskinesia developed after treatment for as short a period as 1 month to as long as 10 years [67].”
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“The situation could be different in recent-onset TD where a prophylactic action of Li might prevent further deterioration of dyskinesia in those patients requiring continued neuroleptic medication (Quitkin et al. 1977).”
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“o :activation' (3-21); e : anxiety-depressiori" (4-28) ; .”
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Prevention/treatment of tardive dyskinesia
Gerlach, J. (1981) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1981.tb02464.x · Cited by 10
“As TD is reversible in the beginning (Quitkin et al. (1977)) it is crucial to detect the syndrome as early as possible.”
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“This was also noted by Quitkin et al (16) who observed that first symptoms of TD rarely persisted if antipsychotics were discontinued and concluded that the length of time symptoms have persisted prior to drug discontinuation may be the major variable determining reversibility of the syndrome.”
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Metadata
- Authors
- Quitkin, F. M., Rifkin, A. E., Gochfeld, L., & Klein, D. F.
- Venue
- American Journal of Psychiatry
- Published
- 1977-01-01
- Volume
- 134
- Issue
- 1
- Pages
- 84-87
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2414414545
- Cited by
- 114
- References
- 16
- Citations by year
- 2022: 2 · 2021: 1 · 2020: 3 · 2019: 2 · 2018: 3 · 2017: 1 · 2014: 1
- FWCI
- 16.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- tardive dyskinesia, antipsychotic adverse effects, reversibility, antipsychotic discontinuation, symptom duration, age of onset, psychiatric patients
- MeSH terms
- Adult, Chlorpromazine, Dyskinesia, Drug-Induced, Female, Fluphenazine, Haloperidol, Humans, Male, Middle Aged, Prognosis, Remission, Spontaneous, Antipsychotic Agents
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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