The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Concordance for the syndrome of autism in 40 pairs of afflicted twins
Abstract
The UCLA Registry for Genetic Studies in Autism was established in 1980 to test the hypothesis that genetic factors may be etiologically significant in subsets of patients. To date 61 pairs of twins have enrolled and 40 meet research diagnostic criteria for autism. The authors found a concordance for autism in these 40 pairs of 95.7% in the monozygotic twins (22 of 23) and 23.5% in the dizygotic twins (four of 17).
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“Studies making use of twin pairs (7)(8)(9)(10)(11), families (12) and populations (11,13) have provided estimates that over half of risk of developing ASD resides with genetic variation”
From Genetics and genomics of autism spectrum disorder: embracing complexity (2015) · cites this paper as [8]
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Cites
(1943) · The Nervous child · Cited by 8,870
INFANTILE AUTISM: A GENETIC STUDY OF 21 TWIN PAIRS
Folstein, S., & Rutter, M. (1977) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1977.tb00443.x · Cited by 1,361
Galdston, I. (1950) · PubMed Central · Cited by 440
Infantile Autism Reviewed: A Decade of Research
DeMyer, M. K., Hingtgen, J. N., & Jackson, R. (1981) · Schizophrenia Bulletin · doi:10.1093/schbul/7.3.388 · Cited by 376
National society for autistic children definition of the syndrome of autism
(1978) · Journal of Autism and Childhood Schizophrenia · doi:10.1007/bf01537864 · Cited by 296
The Incidence of Cognitive Disabilities in the Siblings of Autistic Children
August, G. J., Stewart, M. A., & Tsai, L. (1981) · The British Journal of Psychiatry · doi:10.1192/bjp.138.5.416 · Cited by 240
Implication of sex differences in the familial transmission of infantile autism
Tsai, L., Stewart, M. A., & August, G. J. (1981) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01531682 · Cited by 185
Introduction: The National Society for Autistic Children's Definition of the Syndrome of Autism
RITVO, E. R., & Freeman, B. J. (1978) · Journal of the American Academy of Child Psychiatry · doi:10.1016/s0002-7138(09)61011-6 · Cited by 125
Self-citationThe genetics, if any, of infantile autism and childhood schizophrenia
Hanson, D. R., & Gottesman, I. I. (1976) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01543463 · Cited by 94
Social class factors in autism
RITVO, E. R., Cantwell, D. P., Johnson, E., Clements, M., Benbrook, F., Slagle, S., Kelly, P., & Ritz, M. (1971) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01557350 · Cited by 56
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Research works printed but not linked: 7
- Kanner L, 1943, Nervous Child, 2, 217
- DeMyer MK, Schizophr Bull, 7, 387
- Freeman BJ, 1984, Pediatr Ann, 13, 285
- Kamp LN, 1964, Psychiatr Neurol Neurochir, 67, 143
- Ritvo ER, 1981, Biological Psychiatry 1981: Proceedings of the IlIrd World Congress of Biological Psychiatry
- Thompson JS, 1980, Philadelphia
- Campbell M, Biological Psychiatry: Proceedings of the IlIrd World Congress of Biological Psychiatry
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Curran, S. R., & Bolton, P. (2009) · Springer eBooks · doi:10.1007/978-0-387-76727-7_27 · Cited by 1
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Rowe, D., & Elam, P. (1988) · Journal of Children in Contemporary Society · doi:10.1300/j274v19n03_07 · Cited by 1
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Additional evidence for genetic component in autism
Gans, D. J. (1989) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02212730
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Gupta, V. B. (2004) · CRC Press eBooks · doi:10.1201/9780203026229.ch3
Petot, D. (2014) · Dunod eBooks · doi:10.3917/dunod.peto.2014.01.0481
Nissen, G. (1993) · Springer eBooks · doi:10.1007/978-3-642-97463-2_20
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Nissen, G. (1989) · Springer eBooks · doi:10.1007/978-3-642-97164-8_20
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Allen, G. H., Vilda, B., & Scott-Miller, D. (1992) · Springer eBooks · doi:10.1007/978-1-4612-2774-8_14
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Function and structure of the mirror neuron system in autism
Perkins, T. J. (2014)
Miles (2000) · doi:10.1002/(sici)1096-8628(20000410)91:4
Orsmond, G. I., Seltzer, M. M., Krauss, M. W., & Hong, J. (2003) · American Journal on Mental Retardation · doi:10.1352/0895-8017(2003)108
Donnelly, S. L., Wolpert, C. M., Menold, M. M., Bass, M. P., Gilbert, J. R., Cuccaro, M. L., Delong, G. R., & Pericak-Vance, M. A. (2000) · American Journal of Medical Genetics · doi:10.1002/1096-8628(20000612)96:3
Burger (1998) · doi:10.1002/(sici)1098-2779(1998)4:2
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Remick, R. A., Sadovnick, A. D., Lam, R. W., Zis, A. P., & Yee, I. M. L. (1996) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19960726)67:4
Metadata
- Authors
- RITVO, E. R., Freeman, B. J., MASON-BROTHERS, A., Mo, A., & Ritvo, A.
- Affiliations
- University of California, Los Angeles (US)
- Venue
- American Journal of Psychiatry
- Published
- 1985-01-01
- Volume
- 142
- Issue
- 1
- Pages
- 74-77
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W1717251174
- Cited by
- 378
- References
- 23
- Citations by year
- 2025: 1 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 5 · 2019: 5 · 2018: 6 · 2017: 6 · 2016: 15 · 2015: 14 · 2014: 15 · 2013: 13 · 2012: 22
- FWCI
- 9.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH 31274, MH 30897)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD-04612)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- autism spectrum disorder, twin concordance, monozygotic twins, dizygotic twins, genetic etiology, twin registry
- MeSH terms
- Adolescent, Adult, Age Factors, Autistic Disorder, Birth Order, Child, Child, Preschool, Diseases in Twins, Female, Humans, Male, Models, Genetic, Pregnancy, Registries, Sex Factors, Twins, Dizygotic, Twins, Monozygotic, United States
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