The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
CSF corticotropin-releasing factor-like immunoreactivity in depression and schizophrenia
Abstract
To further investigate the hypothesis that hyperactivity of the hypothalamic-pituitary-adrenal axis in patients with depression may be mediated by hypersecretion of corticotropin-releasing factor (CRF), the authors measured CRF-like immunoreactivity in CSF samples from 138 neurological control, 54 depressed, and 27 nondepressed (23 schizophrenic and four manic) subjects. The CSF CRF concentration was markedly higher (almost twofold) in depressed patients than in control subjects and nondepressed psychiatric patients. The concentration of CSF CRF was slightly but significantly higher in schizophrenic patients than in control subjects. These findings provide further support for the hypothesis that CRF hypersecretion occurs in major depression.
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Cites
Vale, W., Spiess, J., Rivier, C., & Rivier, J. (1981) · Science · doi:10.1126/science.6267699 · Cited by 3,965
Primary structure of corticotropin-releasing factor from ovine hypothalamus
Spiess, J., Rivier, J., Rivier, C., & Vale, W. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.10.6517 · Cited by 424
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Heim, C. (2000) · JAMA · doi:10.1001/jama.284.5.592 · Cited by 1,968
The link between childhood trauma and depression: insights from HPA axis studies in humans
Heim, C., Newport, D. J., Mletzko, T., Miller, A. H., & Nemeroff, C. B. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.03.008 · Cited by 1,704
The Relationship of Depression to Cardiovascular Disease: Epidemiology, Biology, and Treatment
Musselman, D. L., Evans, D. L., & Nemeroff, C. B. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.7.580 · Cited by 1,532
The role of corticotropin-releasing factor in depression and anxiety disorders
Arborelius, L., Owens, M., Plotsky, P., & Nemeroff, C. (1999) · Journal of Endocrinology · doi:10.1677/joe.0.1600001 · Cited by 1,378
Self-citationPostmortem studies in mood disorders indicate altered numbers of neurons and glial cells
Rajkowska, G. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00950-1 · Cited by 822
Metadata
- Venue
- American Journal of Psychiatry
- Published
- 1987-07-01
- Volume
- 144
- Issue
- 7
- Pages
- 873-877
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2421183231
- Cited by
- 336
- References
- 2
- FWCI
- 6.42
- Type
- journal article
- Language
- en
- Open access
- closed
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- CSF corticotropin-releasing factor-like immunoreactivity in depression and schizophrenia. (1987). American Journal of Psychiatry. https://doi.org/10.1176/ajp.144.7.873
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
