Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide

Merrifield, R. B. (1963) · Journal of the American Chemical Society · doi:10.1021/ja00897a025 · Cited by 7,645 · see citing works

NEURAL CONTROL OF THE PITUITARY GLAND

Harris, G. W. (1948) · Physiological Reviews · doi:10.1152/physrev.1948.28.2.139 · Cited by 903 · see citing works

Culture of Enzymatically Dispersed Anterior Pituitary Cells: Functional Validation of a Method

Vale, W., Grant, G., Amoss, M. S., Blackwell, R. E., & Guillemin, R. (1972) · Endocrinology · doi:10.1210/endo-91-2-562 · Cited by 550 · see citing works

Primary structure of corticotropin-releasing factor from ovine hypothalamus

Spiess, J., Rivier, J., Rivier, C., & Vale, W. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.10.6517 · Cited by 424 · see citing works

HUMORAL HYPOTHALAMIC CONTROL OF ANTERIOR PITUITARY: A STUDY WITH COMBINED TISSUECULTURES

Guillemin, R., & Rosenberg, B. (1955) · Endocrinology · doi:10.1210/endo-57-5-599 · Cited by 368 · see citing works

THE PREPARATION, PURIFICATION, AND AMINO ACID SEQUENCE OF A POLYPEPTIDE RENIN SUBSTRATE

Skeggs, L. T., Kahn, J. R., Lentz, K. E., & Shumway, N. P. (1957) · The Journal of Experimental Medicine · doi:10.1084/jem.106.3.439 · Cited by 316 · see citing works

Isolation and sequence analysis of a somatostatin-like polypeptide from ovine hypothalamus

Spiess, J., Villarreal, J. A., & Vale, W. (1981) · Biochemistry · doi:10.1021/bi00510a038 · Cited by 214 · see citing works

Active polypeptides: from amphibian skin to gastrointestinal tract and brain of mammals

Erspamer, V. (1980) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(80)90060-7 · Cited by 205 · see citing works

Effects of Purified Hypothalamic Corticotropin-Releasing Factor and Other Substances on the Secretion of Adrenocorticotropin and β-Endorphin-Like Immunoactivities inVitro*

Vale, W., RIVIER, C. L., YANG, L., Minick, S., & Guillemin, R. (1978) · Endocrinology · doi:10.1210/endo-103-5-1910 · Cited by 179 · see citing works

Corticotrophin releasing factor may be modulated vasopressin

Gillies, G. E., & Lowry, P. (1979) · Nature · doi:10.1038/278463a0 · Cited by 174 · see citing works

β-endorphin concentration in the brain of intact and hypophysectomized rats

Ogawa, N., Panerai, A. E., Lee, S., et al. (1979) · Life Sciences · doi:10.1016/0024-3205(79)90261-3 · Cited by 130 · see citing works

A device coupled to a modified sequenator for the automated conversion of anilinothiazolinones into PTH amino acids

Wittmann‐Liebold, B., Graffunder, H., & Kohls, H. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90117-2 · Cited by 123 · see citing works

THE ACTH-RELEASING ACTIVITY OF EXTRACTS OF THE POSTERIOR LOBE OF THE PITUITARY IN VIVO1

McCann, S. M. (1957) · Endocrinology · doi:10.1210/endo-60-5-664 · Cited by 93 · see citing works

THE RELEASE OF CORTICOTROPHIN BY ANTERIOR PITUITARY TISSUE IN VITRO

Saffran, M., & Schally, A. V. (1955) · Canadian Journal of Biochemistry and Physiology · doi:10.1139/y55-054 · Cited by 86 · see citing works

Assays for Corticotropin-Releasing Factor (CRF) Using Rats Treated with Morphine, Chlorpromazine, Dexamethasone and Nembutal

Arimura, A., Saito, T., & Schally, A. V. (1967) · Endocrinology · doi:10.1210/endo-81-2-235 · Cited by 78 · see citing works

Total solid-phase synthesis of porcine gut gastrin releasing peptide (GRP), a mammalian bombesin

MAERKI, W., Spiess, J., Tache, Y., et al. (1981) · Journal of the American Chemical Society · doi:10.1021/ja00401a040 · Cited by 72 · see citing works

Evidence for the Existence of Two Corticotrophin-releasing Factors, α and β

Schally, A. V., Andersen, R. N., LIPSCOMB, H. S., et al. (1960) · Nature · doi:10.1038/1881192a0 · Cited by 59 · see citing works

Isolated Pituitary Cells: CRF-Like Activity of Neurohypophysial and Related Polypeptides

PORTANOVA, R., & Sayers, G. (1973) · Experimental Biology and Medicine · doi:10.3181/00379727-143-37386 · Cited by 55 · see citing works

Isolation, structural elucidation and synthesis of a tetradecapeptide with in vitro ACTH-releasing activity corresponding to residues 33–46 of the α-chain of porcine hemoglobin

Schally, A. V., Huang, W. Y., Redding, T. W., et al. (1978) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(78)90914-2 · Cited by 43 · see citing works

NURAL PATHWAYS INVOLVED IN ACTH REGULATION

Palkovits, M. (1977) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1977.tb41875.x · Cited by 29 · see citing works

FURTHER STUDY OF AN ACTH-RELEASING PROTEIN FROM HYPOPHYSEAL PORTAL VESSEL PLASMA1

Porter, J. C., & Rumsfeld, H. W. (1959) · Endocrinology · doi:10.1210/endo-64-6-948 · Cited by 28 · see citing works

Properties of the Corticotrophin-Releasing Factor of the Rat Median Eminence1

CHAN, L. T., SCHAAL, S. M., & Saffran, M. (1969) · Endocrinology · doi:10.1210/endo-85-4-644 · Cited by 28 · see citing works

Purification of Hypothalamic Corticotrophin-Releasing Factor (CRF) Of Ovine Origin

DHARIWAL, A. P. S., Antunes‐Rodrigues, J., Reeser, F. H., et al. (1966) · Experimental Biology and Medicine · doi:10.3181/00379727-121-30682 · Cited by 16 · see citing works

STUDIES ON THE NATURE OF CORTICOTROPHIN RELEASING HORMONE AND ITS PARTIAL PURIFICATION FROM PORCINE HYPOTHALAMI

Cooper, D. M. F., Synetos, D., Christie, R. B., et al. (1976) · Journal of Endocrinology · doi:10.1677/joe.0.0710171 · Cited by 12 · see citing works

Isolation of N-acetylaspartic acid from hypothalamic tissue and significance of its ACTH-releasing activity

Knudsen, R., Lam, Y.-K., Folkers, K., et al. (1978) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(78)91306-2 · Cited by 11 · see citing works

Stress and disorders of the stress system

Chrousos, G. P. (2009) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2009.106 · Cited by 3,215 · see citing works

Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress

Tsigos, C., & Chrousos, G. P. (2002) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(02)00429-4 · Cited by 2,822 · see citing works

The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress

Smith, S. M., & Vale, W. W. (2006) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2006.8.4/ssmith · Cited by 1,948 · see citing works

Stress Effects on Neuronal Structure: Hippocampus, Amygdala, and Prefrontal Cortex

McEwen, B. S., Nasca, C., & Gray, J. D. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2015.171 · Cited by 1,574 · see citing works

Stress hormones: their interaction and regulation

Axelrod, J., & Reisine, T. D. (1984) · Science · doi:10.1126/science.6143403 · Cited by 1,527 · see citing works

Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients

Nemeroff, C. B., Widerlöv, E., Bissette, G., Walléus, H., Karlsson, I., Eklund, K., Kilts, C. D., Loosen, P. T., & Vale, W. (1984) · Science · doi:10.1126/science.6334362 · Cited by 1,485 · see citing works

Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

Dunn, A. J., & Berridge, C. W. (1990) · Brain Research Reviews · doi:10.1016/0165-0173(90)90012-d · Cited by 1,352 · see citing works

CRF and CRF receptors: role in stress responsivity and other behaviors

Bale, T. L., & Vale, W. W. (2004) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.44.101802.121410 · Cited by 1,270 · see citing works

Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action

TURNBULL, A. V., & RIVIER, C. L. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.1.1 · Cited by 1,297 · see citing works

Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin

Gillies, G. E., Linton, E. A., & Lowry, P. J. (1982) · Nature · doi:10.1038/299355a0 · Cited by 965 · see citing works

The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders

Binder, E. B. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.05.021 · Cited by 968 · see citing works

Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1

Timpl, P., Spanagel, R., Sillaber, I., Kresse, A., Reul, J. M. H. M., Stalla, G. K., Blanquet, V., Steckler, T., Holsboer, F., & Wurst, W. (1998) · Nature Genetics · doi:10.1038/520 · Cited by 919 · see citing works

Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor

Lewis, K., Li, C., Perrin, M. H., Blount, A., Kunitake, K., Donaldson, C., Vaughan, J., Reyes, T. M., Gulyas, J., Fischer, W., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.121165198 · Cited by 925 · see citing works

Neuroendocrine pharmacology of stress

Carrasco, G. A., & Van de Kar, L. D. (2003) · European Journal of Pharmacology · doi:10.1016/s0014-2999(03)01285-8 · Cited by 914 · see citing works

Corticotropin Releasing Factor Receptor 1–Deficient Mice Display Decreased Anxiety, Impaired Stress Response, and Aberrant Neuroendocrine Development

Smith, G. W., Aubry, J.-M., Dellu, F., Contarino, A., Bilezikjian, L. M., Gold, L. H., Chen, R., Marchuk, Y., Hauser, C., Bentley, C. A., et al. (1998) · Neuron · doi:10.1016/s0896-6273(00)80491-2 · Cited by 892 · see citing works

Urocortin II: A Member of the Corticotropin-Releasing Factor (CRF) Neuropeptide Family that Is Selectively Bound by Type 2 CRF Receptors

Reyes, T. M., Lewis, K., Perrin, M. H., Kunitake, K. S., Vaughan, J., Arias, C. A., Hogenesch, J. B., Gulyas, J., Rivier, J., Vale, W. W., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.051626398 · Cited by 887 · see citing works

Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress

Slominski, A., Wortsman, J., Luger, T., Paus, R., & Solomon, S. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.3.979 · Cited by 776 · see citing works

Sex differences and stress across the lifespan

Bale, T. L., & Epperson, C. N. (2015) · Nature Neuroscience · doi:10.1038/nn.4112 · Cited by 751 · see citing works

Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor.

Maier, S. F., & Watkins, L. R. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.03.021 · Cited by 737 · see citing works

Sex differences in stress-related psychiatric disorders: neurobiological perspectives

Bangasser, D. A., & Valentino, R. J. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2014.03.008 · Cited by 737 · see citing works

Hypothalamic–pituitary–adrenal and hypothalamic–pituitary–gonadal axes: sex differences in regulation of stress responsivity

Oyola, M. G., & Handa, R. J. (2017) · Stress · doi:10.1080/10253890.2017.1369523 · Cited by 710 · see citing works

Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated

Zobel, A. W., Nickel, T., Künzel, H. E., Ackl, N., Sonntag, A., Ising, M., & Holsboer, F. (2000) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(00)00016-9 · Cited by 705 · see citing works

Revisiting the Stress Concept: Implications for Affective Disorders

McEwen, B. S., & Akil, H. (2020) · The Journal of Neuroscience · doi:10.1523/jneurosci.0733-19.2019 · Cited by 686 · see citing works

The organization of the stress system and its dysregulation in depressive illness

Gold, P. W. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.163 · Cited by 654 · see citing works

PSYCHONEUROENDOCRINOLOGY OF DEPRESSION

Plotsky, P. M., Owens, M. J., & Nemeroff, C. B. (1998) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70006-x · Cited by 672 · see citing works

The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety

Holsboer, F. (1999) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(98)90056-5 · Cited by 654 · see citing works

Corticotropin-releasing factor, norepinephrine, and stress

Koob, G. F. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00164-x · Cited by 629 · see citing works

Intraadrenal interactions in the regulation of adrenocortical steroidogenesis.

Ehrhart-Bornstein, M., Hinson, J. P., Bornstein, S. R., Scherbaum, W. A., & Vinson, G. P. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.2.0326 · Cited by 600 · see citing works

Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system

Whitnall, M. H. (1993) · Progress in Neurobiology · doi:10.1016/0301-0082(93)90035-q · Cited by 582 · see citing works

Anxiety, depression, and the microbiome: A role for gut peptides

Lach, G., Schellekens, H., Dinan, T. G., & Cryan, J. F. (2018) · Neurotherapeutics · doi:10.1007/s13311-017-0585-0 · Cited by 573 · see citing works

Convergent regulation of locus coeruleus activity as an adaptive response to stress

Valentino, R. J., & Van Bockstaele, E. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.11.062 · Cited by 569 · see citing works

The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors

Bruchas, M. R., Land, B. B., & Chavkin, C. (2010) · Brain Research · doi:10.1016/j.brainres.2009.08.062 · Cited by 544 · see citing works

Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain

Chang, C.-P., Pearse, R. V., O'Connell, S., & Rosenfeld, M. G. (1993) · Neuron · doi:10.1016/0896-6273(93)90230-o · Cited by 537 · see citing works

Modulation of stress-induced ACTH release by corticotropin-releasing factor, catecholamines and vasopressin

Rivier, C., & Vale, W. (1983) · Nature · doi:10.1038/305325a0 · Cited by 539 · see citing works

Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need

Muglia, L., Jacobson, L., Dikkes, P., & Majzoub, J. A. (1995) · Nature · doi:10.1038/373427a0 · Cited by 524 · see citing works

Distribution of corticotropin-releasing factor receptor mRNA expression in the rat brain and pituitary.

Potter, E., Sutton, S., Donaldson, C., Chen, R., Perrin, M., Lewis, K., Sawchenko, P. E., & Vale, W. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.19.8777 · Cited by 514 · see citing works

A key role for corticotropin-releasing factor in alcohol dependence

Heilig, M., & Koob, G. F. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.06.006 · Cited by 503 · see citing works

Activation of Corticotropin-Releasing Factor in the Limbic System During Cannabinoid Withdrawal

Rodrı́guez de Fonseca, F., Carrera, M. R. A., Navarro, M., Koob, G. F., & Weiss, F. (1997) · Science · doi:10.1126/science.276.5321.2050 · Cited by 499 · see citing works

Differential steroid hormone and neural influences on peptide mRNA levels in CRH cells of the paraventricular nucleus: a hybridization histochemical study in the rat

Swanson, L. W., & Simmons, D. M. (1989) · Journal of Comparative Neurology · doi:10.1002/cne.902850402 · Cited by 478 · see citing works

Stress Hormone Regulation: Biological Role and Translation into Therapy

Holsboer, F., & Ising, M. (2010) · Annual Review of Psychology · doi:10.1146/annurev.psych.093008.100321 · Cited by 473 · see citing works

Untitled work

Slominski (2012) · doi:10.1007/978-3-642-19683-6_1 · Cited by 461 · see citing works

Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice

Elliott, E., Ezra-Nevo, G., Regev, L., Neufeld-Cohen, A., & Chen, A. (2010) · Nature Neuroscience · doi:10.1038/nn.2642 · Cited by 436 · see citing works

Induction of corticotropin-releasing hormone gene expression by glucocorticoids: implication for understanding the states of fear and anxiety and allostatic load

Schulkin, J., W. Gold, P., & S. McEwen, B. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(97)00099-1 · Cited by 423 · see citing works

Psychoneuroendocrine processes in human pregnancy influence fetal development and health

Wadhwa, P. D. (2005) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2005.02.004 · Cited by 420 · see citing works

Evidence of direct estrogenic regulation of human corticotropin-releasing hormone gene expression. Potential implications for the sexual dimophism of the stress response and immune/inflammatory reaction.

Vamvakopoulos, N. C., & Chrousos, G. P. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116782 · Cited by 422 · see citing works

Gonadal steroid hormones and the hypothalamo–pituitary–adrenal axis

Handa, R. J., & Weiser, M. J. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2013.11.001 · Cited by 408 · see citing works

Elevated maternal cortisol early in pregnancy predicts third trimester levels of placental corticotropin releasing hormone (CRH): Priming the placental clock

Sandman, C. A., Glynn, L., Schetter, C. D., Wadhwa, P., Garite, T., Chicz-DeMet, A., & Hobel, C. (2006) · Peptides · doi:10.1016/j.peptides.2005.10.002 · Cited by 411 · see citing works

Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal

Rassnick, S., Heinrichs, S. C., Britton, K. T., & Koob, G. F. (1993) · Brain Research · doi:10.1016/0006-8993(93)91352-s · Cited by 407 · see citing works

Sex differences in corticotropin-releasing factor receptor signaling and trafficking: potential role in female vulnerability to stress-related psychopathology

Bangasser, D. A., Curtis, A., Reyes, B. A. S., Bethea, T. T., Parastatidis, I., Ischiropoulos, H., Van Bockstaele, E. J., & Valentino, R. J. (2010) · Molecular Psychiatry · doi:10.1038/mp.2010.66 · Cited by 401 · see citing works

Modulation of learning and anxiety by corticotropin-releasing factor (CRF) and stress: differential roles of CRF receptors 1 and 2

Radulovic, J., Rühmann, A., Liepold, T., & Spiess, J. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-12-05016.1999 · Cited by 402 · see citing works

Key role of CRF in the skin stress response system

Slominski, A. T., Zmijewski, M. A., Zbytek, B., Tobin, D. J., Theoharides, T. C., & Rivier, J. (2013) · Endocrine Reviews · doi:10.1210/er.2012-1092 · Cited by 400 · see citing works

Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor

Valdez, G. R., Roberts, A. J., Chan, K., Davis, H., Brennan, M., Zorrilla, E. P., & Koob, G. F. (2002) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2002.tb02448.x · Cited by 387 · see citing works

Corticotropin-releasing factor within the central nucleus of the amygdala mediates enhanced ethanol self-administration in withdrawn, ethanol-dependent rats

Funk, C. K., O'Dell, L. E., Crawford, E. F., & Koob, G. F. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.3096-06.2006 · Cited by 381 · see citing works

Development and function of the human fetal adrenal cortex: a key component in the feto-placental unit

Ishimoto, H., & Jaffe, R. B. (2011) · Endocrine Reviews · doi:10.1210/er.2010-0001 · Cited by 379 · see citing works

Rearing condition and rh5-HTTLPR interact to influence limbic-hypothalamic-pituitary-adrenal axis response to stress in infant macaques

Barr, C. S., Newman, T. K., Shannon, C., Parker, C., Dvoskin, R. L., Becker, M. L., Schwandt, M., Champoux, M., Lesch, K. P., Goldman, D., et al. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.12.008 · Cited by 385 · see citing works

The Effect of Long-Term Glucocorticoid Therapy on Pituitary–Adrenal Responses to Exogenous Corticotropin-Releasing Hormone

Schlaghecke, R., Kornely, E., Santen, R. T., & Ridderskamp, P. (1992) · New England Journal of Medicine · doi:10.1056/nejm199201233260403 · Cited by 381 · see citing works

Allostasis, amygdala, and anticipatory angst

Schulkin, J., McEwen, B. S., & Gold, P. W. (1994) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(94)90051-5 · Cited by 380 · see citing works

Hypercortisolemia and depression

Gillespie, C. F., & Nemeroff, C. B. (2005) · Psychosomatic Medicine · doi:10.1097/01.psy.0000163456.22154.d2 · Cited by 361 · see citing works

Stress and Preterm Birth: Neuroendocrine, Immune/Inflammatory, and Vascular Mechanisms

Wadhwa, P. D., Culhane, J. F., Rauh, V., & Barve, S. S. (2001) · Maternal and Child Health Journal · doi:10.1023/a:1011353216619 · Cited by 336 · see citing works

Glucocorticoid actions on synapses, circuits, and behavior: Implications for the energetics of stress

Myers, B., McKlveen, J. M., & Herman, J. P. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2013.12.003 · Cited by 318 · see citing works

Effects of Cytokines on Cerebral Neurotransmission: Comparison with the Effects of Stress

Dunn, A. J., Wang, J., & Ando, T. (1999) · Advances in Experimental Medicine and Biology · doi:10.1007/978-0-585-37970-8_8 · Cited by 316 · see citing works

Stress, infection and preterm birth: a biobehavioural perspective

Wadhwa, P. D., Culhane, J. F., Rauh, V., Barve, S. S., Hogan, V., Sandman, C. A., Hobel, C. J., Chicz‐DeMet, A., Dunkel‐Schetter, C., Garite, T. J., et al. (2001) · Paediatric and Perinatal Epidemiology · doi:10.1046/j.1365-3016.2001.00005.x · Cited by 309 · see citing works

Corticotropin-releasing factor potentiates acoustic startle in rats: Blockade by chlordiazepoxide

Swerdlow, N. R., Geyer, M. A., Vale, W. W., & Koob, G. F. (1986) · Psychopharmacology · doi:10.1007/bf00652231 · Cited by 299 · see citing works

Effect of a corticotropin releasing hormone receptor antagonist on colonic sensory and motor function in patients with irritable bowel syndrome

Sagami, Y., Shimada, Y., Tayama, J., Nomura, T., Satake, M., Endo, Y., Shoji, T., Karahashi, K., Hongo, M., & Fukudo, S. (2004) · Gut · doi:10.1136/gut.2003.018911 · Cited by 291 · see citing works

The medial prefrontal cortex: coordinator of autonomic, neuroendocrine and behavioural responses to stress

McKlveen, J. M., Myers, B., & Herman, J. P. (2015) · Journal of Neuroendocrinology · doi:10.1111/jne.12272 · Cited by 273 · see citing works

Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats

Funk, C. K., Zorrilla, E. P., Lee, M.-J., Rice, K. C., & Koob, G. F. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.063 · Cited by 276 · see citing works

Structural and functional evolution of vertebrate neuroendocrine stress systems

Denver, R. J. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04433.x · Cited by 273 · see citing works

Cutaneous hypothalamic–pituitary–adrenal axis homolog: regulation by ultraviolet radiation

Skobowiat, C., Dowdy, J. C., Sayre, R. M., Tuckey, R. C., & Slominski, A. (2011) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00217.2011 · Cited by 269 · see citing works

HPA Axis‐Rhythms

Spiga, F., Walker, J. J., Terry, J. R., & Lightman, S. L. (2014) · Comprehensive Physiology · doi:10.1002/cphy.c140003 · Cited by 267 · see citing works

Hormonal Treatments for Major Depressive Disorder: State of the Art

Dwyer, J. B., Aftab, A., Radhakrishnan, R., Widge, A., Rodriguez, C. I., Carpenter, L. L., Nemeroff, C. B., McDonald, W. M., Kalin, N. H., & APA Council of Research Task Force on Novel Biomarkers and Treatments (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.19080848 · Cited by 252 · see citing works

60 YEARS OF NEUROENDOCRINOLOGY: Redefining neuroendocrinology: stress, sex and cognitive and emotional regulation

McEwen, B. S., Gray, J. D., & Nasca, C. (2015) · Journal of Endocrinology · doi:10.1530/joe-15-0121 · Cited by 253 · see citing works

Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake

Olive, M. F., Koenig, H. N., Nannini, M. A., & Hodge, C. W. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00748-1 · Cited by 237 · see citing works

The Impact of the Nonpeptide Corticotropin-Releasing Hormone Antagonist Antalarmin on Behavioral and Endocrine Responses to Stress**This research was supported by NIMH Grant MH-50479 and the Undergraduate Research Opportunities Program at the University of Colorado at Boulder.

Deak, T., Nguyen, K. T., Ehrlich, A. L., Watkins, L. R., Spencer, R. L., Maier, S. F., Licinio, J., Wong, M.-L., Chrousos, G. P., Webster, E., et al. (1999) · Endocrinology · doi:10.1210/endo.140.1.6415 · Cited by 242 · see citing works

Role of stress, corticotrophin releasing factor (CRF) and amygdala plasticity in chronic anxiety

Shekhar, A., Truitt, W., Rainnie, D., & Sajdyk, T. (2005) · Stress · doi:10.1080/10253890500504557 · Cited by 237 · see citing works

Dissociation of oxytocin, vasopressin and corticotropin secretion during different types of stress

Gibbs, D. M. (1984) · Life Sciences · doi:10.1016/0024-3205(84)90241-8 · Cited by 233 · see citing works

Neuroendocrine Mechanisms in Pregnancy and Parturition

Petraglia, F., Imperatore, A., & Challis, J. R. G. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0019 · Cited by 224 · see citing works

Serial assessment of corticotropin-releasing hormone response after dexamethasone in depression Implications for pathophysiology of DST nonsuppression

Holsboer, F., von Bardeleben, U., Wiedemann, K., Müller, O. A., & Stalla, G. K. (1987) · Biological Psychiatry · doi:10.1016/0006-3223(87)90237-x · Cited by 221 · see citing works

Acute stress increases interstitial fluid amyloid-β via corticotropin-releasing factor and neuronal activity

Kang, J.-E., Cirrito, J. R., Dong, H., Csernansky, J. G., & Holtzman, D. M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700148104 · Cited by 219 · see citing works

A new model for the HPA axis explains dysregulation of stress hormones on the timescale of weeks

Karin, O., Raz, M., Tendler, A., Bar, A., Korem Kohanim, Y., Milo, T., & Alon, U. (2020) · Molecular Systems Biology · doi:10.15252/msb.20209510 · Cited by 200 · see citing works

Behavioral effects of neuropeptides in rodent models of depression and anxiety

Rotzinger, S., Lovejoy, D. A., & Tan, L. A. (2010) · Peptides · doi:10.1016/j.peptides.2009.12.015 · Cited by 211 · see citing works

CRH and the immune system

Karalis, K., Muglia, L. J., Bae, D., Hilderbrand, H., & Majzoub, J. A. (1997) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(96)00178-6 · Cited by 203 · see citing works

The molecular physiology of CRH neurons

Aguilera, G., & Liu, Y. (2012) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2011.08.002 · Cited by 198 · see citing works

Glucocorticoids, chronic stress, and obesity

Dallman, M. F., Pecoraro, N. C., La Fleur, S. E., Warne, J. P., Ginsberg, A. B., Akana, S. F., Laugero, K. C., Houshyar, H., Strack, A. M., Bhatnagar, S., et al. (2006) · Progress in Brain Research · doi:10.1016/s0079-6123(06)53004-3 · Cited by 198 · see citing works

Neuropeptide receptor ligands as drugs for psychiatric diseases: the end of the beginning?

Griebel, G., & Holsboer, F. (2012) · Nature Reviews Drug Discovery · doi:10.1038/nrd3702 · Cited by 194 · see citing works

High-priority communication I Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence

Valdez, G. R., Zorrilla, E. P., Roberts, A. J., & Koob, G. F. (2003) · Alcohol · doi:10.1016/s0741-8329(03)00020-x · Cited by 186 · see citing works

Arginine vasopressin potentiates adrenocorticotropin release induced by ovine corticotropin-releasing factor

DeBold, C. R., Sheldon, W. R., DeCherney, G. S., Jackson, R. V., Alexander, A. N., Vale, W., Rivier, J., & Orth, D. N. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111240 · Cited by 189 · see citing works

The origin of glucocorticoid hormone oscillations

Walker, J. J., Spiga, F., Waite, E., Zhao, Z., Kershaw, Y., Terry, J. R., & Lightman, S. L. (2012) · PLoS Biology · doi:10.1371/journal.pbio.1001341 · Cited by 189 · see citing works

GABAergic innervation of corticotropin-releasing hormone (CRH)-secreting parvocellular neurons and its plasticity as demonstrated by quantitative immunoelectron microscopy

Miklós, I. H., & Kovács, K. J. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00147-1 · Cited by 182 · see citing works

Neural Regulation of the Stress Response: The Many Faces of Feedback

Myers, B., McKlveen, J. M., & Herman, J. P. (2012) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-012-9801-y · Cited by 175 · see citing works

Development of adrenal cortex zonation

Xing, Y., Lerario, A. M., Rainey, W., & Hammer, G. D. (2015) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2015.02.001 · Cited by 174 · see citing works

Glucocorticoid Negative Feedback Selectively Targets Vasopressin Transcription in Parvocellular Neurosecretory Neurons

Kovács, K. J., Földes, A., & Sawchenko, P. E. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-10-03843.2000 · Cited by 172 · see citing works

Reduction of Stress-Induced Behavior by Antagonism of Corticotropin-Releasing Hormone 2 (CRH₂) Receptors in Lateral Septum or CRH₁Receptors in Amygdala

Bakshi, V. P., Smith-Roe, S., Newman, S. M., Grigoriadis, D. E., & Kalin, N. H. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-07-02926.2002 · Cited by 171 · see citing works

Stress, cortisol, and obesity: A role for cortisol responsiveness in identifying individuals prone to obesity

Hewagalamulage, S. D., Lee, T. K., Clarke, I. J., & Henry, B. A. (2016) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2016.03.004 · Cited by 167 · see citing works

Modulation of dendritic differentiation by corticotropin-releasing factor in the developing hippocampus

Chen, Y., Bender, R. A., Brunson, K. L., Pomper, J. K., Grigoriadis, D. E., Wurst, W., & Baram, T. Z. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403975101 · Cited by 166 · see citing works

Stress is a principal factor that promotes tobacco use in females

Torres, O. V., & O'Dell, L. E. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2015.04.005 · Cited by 164 · see citing works

Oxytocin and Social Relationships: From Attachment to Bond Disruption

Bosch, O. J., & Young, L. J. (2017) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2017_10 · Cited by 162 · see citing works

Inhibitory effect of oxytocin on corticotrope function in humans: are vasopressin and oxytocin ying–yang neurohormones?

Legros, J.-J. (2001) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(01)00018-x · Cited by 159 · see citing works

Rapid stress-induced elevations in corticotropin-releasing hormone mRNA in rat central amygdala nucleus and hypothalamic paraventricular nucleus: An in situ hybridization analysis

Hsu, D. T., Chen, F.-L., Takahashi, L. K., & Kalin, N. H. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00032-8 · Cited by 154 · see citing works

Corticotropin releasing hormone and the skin

Slominski, A. (2006) · Frontiers in bioscience · doi:10.2741/1966 · Cited by 157 · see citing works

GABAA receptor-acting neurosteroids: a role in the development and regulation of the stress response

Gunn, B. G., Cunningham, L., Mitchell, S. G., Swinny, J. D., Lambert, J. J., & Belelli, D. (2015) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2014.06.001 · Cited by 149 · see citing works

Comparison of the Ability of Thyroxine and Triiodothyronine to Suppress TRH-Induced TSH Secretion by Perifused Rat Anterior Pituitary Fragments

Ikeda, H., UCHIMURA, H., & Greer, M. A. (2008) · Neuroendocrinology · doi:10.1159/000124157 · Cited by 4 · see citing works

Studies on Autoregulation of Prolactin Secretion from Perifused Rat Pituitary Glands in the Basal and Thyrotropin-Releasing Hormone-Stimulated States*

MALTZ, B. L., Buckman, M. T., Peake, G. T., et al. (1978) · Endocrinology · doi:10.1210/endo-103-2-480 · Cited by 13 · see citing works

Inverse Effects of Purified Hypothalamic TRF on the Acute Secretion of TSH and ACTH

Sakiz, E., & Guillemin, R. (1965) · Endocrinology · doi:10.1210/endo-77-5-797 · Cited by 20 · see citing works

THE SECRETION OF DEHYDROEPIANDROSTERONE AND DEHYDROEPIANDROSTERONE SULPHATE IN MAN

Nieschlag, E., Loriaux, D. L., Ruder, H. J., Zucker, I., Kirschner, M. A., & LIPSETT, M. B. (1973) · Journal of Endocrinology · doi:10.1677/joe.0.0570123 · Cited by 209 · see citing works

Epidermal Growth Factor Stimulates Growth Hormone Secretion from Superfused Rat Adenohypophyseal Fragments

Ikeda, H., Mitsuhashi, T., Kubota, K., et al. (1984) · Endocrinology · doi:10.1210/endo-115-2-556 · Cited by 49 · see citing works