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Cited by 369

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Course and outcome in bipolar affective disorder: a longitudinal follow- up study

·1995·American Journal of Psychiatry
DOI 10.1176/ajp.152.3.379
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Abstract

OBJECTIVE: A number of recent studies have questioned whether, despite modern treatment, the natural course of bipolar illness today still involves multiple relapses and impaired psychosocial functioning. This prospective follow-up study examined longitudinal outcome in a large group of inpatients with affective disorders. METHOD: Fifty-one bipolar manic patients and 49 unipolar depressed patients were interviewed three times: 1) during hospitalization, 2) approximately 2 years after discharge, and 3) approximately 4.5 years after discharge. Subjects were treated under routine conditions and assessed for global adjustment, rehospitalization, and work and social functioning. RESULTS: Only 41% of the bipolar group had a good overall outcome by the time of the 4.5-year follow-up. The bipolar patients had more severe work impairment than the unipolar group. More than one-half of the bipolar patients were rehospitalized at least once during the 4.5-year follow-up period. Outcome for both diagnostic groups improved significantly over time. CONCLUSIONS: Many contemporary bipolar patients demonstrate gradual improvement in the first several years after hospitalization. However, a subgroup approaching 60% still experience poor posthospital adjustment in one or more areas of functioning.

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Metadata

Venue
American Journal of Psychiatry
Publisher
American Psychiatric Association Publishing
Published
1995-03-01
Volume
152
Issue
3
Pages
379-384
ISSN
  • 0002-953X (ISSN-L)
  • 1535-7228
DOI
10.1176/ajp.152.3.379
OpenAlex
W2151089765
Cited by
369
References
15
FWCI
6.92
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Course and outcome in bipolar affective disorder: a longitudinal follow- up study. https://app.cochat.ai/papers/10.1176/ajp.152.3.379
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Course and outcome in bipolar affective disorder: a longitudinal follow- up study. (1995). American Journal of Psychiatry. https://doi.org/10.1176/ajp.152.3.379

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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