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Cited by 253Suicide and Self-Harm StudiesHomicide, Infanticide, and Child AbuseBipolar Disorder and Treatment

The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.

Sex Differences in Clinical Predictors of Suicidal Acts After Major Depression: A Prospective Study

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Oquendo, Maria A., Bongiovi-Garcia, Mary E., Galfalvy, Hanga, Goldberg, Pablo H., Grunebaum, Michael F., Burke, Ainsley K., Mann, J. John·2007·American Journal of Psychiatry
DOI 10.1176/ajp.2007.164.1.134PMC PMC3785095
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Abstract

Objective: Whether sex differences exist in clinical risk factors associated with suicidal behavior is unknown. The authors postulated that among men with a major depressive episode, aggression, hostility, and history of substance misuse increase risk for future suicidal behavior, while depressive symptoms, childhood history of abuse, fewer reasons for living, and borderline personality disorder do so in depressed women. Method: Patients with DSM-III-R major depression or bipolar disorder seeking treatment for a major depressive episode (N=314) were followed for 2 years. Putative predictors were tested with Cox proportional hazards regression analysis. Results: During follow-up, 16.6% of the patients attempted or committed suicide. Family history of suicidal acts, past drug use, cigarette smoking, borderline personality disorder, and early parental separation each more than tripled the risk of future suicidal acts in men. For women, the risk for future suicidal acts was sixfold greater for prior suicide attempters; each past attempt increased future risk threefold. Suicidal ideation, lethality of past attempts, hostility, subjective depressive symptoms, fewer reasons for living, comorbid borderline personality disorder, and cigarette smoking also increased the risk of future suicidal acts for women. Conclusions: These findings suggest that the importance of risk factors for suicidal acts differs in depressed men and women. This knowledge may improve suicide risk evaluation and guide future research on suicide assessment and prevention.

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  1. Spitzer RL, 1990, Gibbon M
  2. 10.1037/0022-006X.47.2.343 · DOI · Paper page
  3. Durkheim, 1951, Translated by Spaulding JA

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Metadata

Authors
Oquendo, M. A., Bongiovi-Garcia, M. E., Galfalvy, H., Goldberg, P. H., Grunebaum, M. F., Burke, A. K., & Mann, J. J.
Affiliations
New York State Psychiatric Institute (US)
ORCID
Venue
American Journal of Psychiatry
Publisher
American Psychiatric Association Publishing
Published
2007-01
Volume
164
Issue
1
Pages
134-141
ISSN
  • 0002-953X (ISSN-L)
  • 1535-7228
DOI
10.1176/ajp.2007.164.1.134
PMC
PMC3785095
OpenAlex
W1989884455
Cited by
249
References
51
Citations by year
2026: 3 · 2025: 6 · 2024: 8 · 2023: 3 · 2022: 11 · 2021: 11 · 2020: 13 · 2019: 6 · 2018: 15 · 2017: 11 · 2016: 21 · 2015: 10 · 2014: 22 · 2013: 17 · 2012: 12
FWCI
23.91
Type
journal article
Language
en
Open access
Locations
  • American Journal of Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • American Foundation for Suicide Prevention
  • Eli Lilly and Company
  • Pfizer
  • GlaxoSmithKline
  • National Alliance for Research on Schizophrenia and Depression
  • H. Lundbeck A/S
  • National Institute on Alcohol Abuse and Alcoholism
  • National Institute of Mental Health (MH 62185, R01MH059710, MH48514, R01MH048514, MH 59710, P50MH062185)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
  • Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Keywords
sex differences, suicidal behavior, major depressive disorder, suicide risk factors, suicide attempts, borderline personality disorder, childhood abuse, parental separation, cigarette smoking, substance abuse, hostility, reasons for living, suicidal ideation, bipolar disorder, suicide prevention
MeSH terms
Suicide Prevention, Adolescent, Adult, Aged, Borderline Personality Disorder, Child, Child Abuse, Major Depressive Disorder, Female, Humans, Male, Middle Aged, Prognosis, Prospective Studies, Psychiatric Status Rating Scales, Risk Factors, Sex Factors, Smoking, Suicide, Suicide, Attempted, Comorbidity, Diagnosis, Dual (Psychiatry), Substance-Related Disorders

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