The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Stimulant-Induced Enhanced Sexual Desire as a Potential Contributing Factor in HIV Transmission
Abstract
OBJECTIVE: Stimulant abuse is associated with an increased risk of contracting human immunodeficiency virus (HIV). Although sharing of contaminated needles is one of the routes by which HIV is spread, noninjection abusers are also at high risk. The authors investigated the effect of the stimulant drug methylphenidate (given intravenously) on sexual desire as a possible contributing factor to risky sexual behavior associated with the contraction of HIV. METHOD: The effects of intravenous methylphenidate (0.5 mg/kg) on self-reports of sexual desire (rated from 0-10) were evaluated in 39 comparison subjects and 39 cocaine abusers. RESULTS: Intravenous methylphenidate significantly increased self-reports of sexual desire in comparison subjects (1.4 versus 3.7) and cocaine abusers (2.8 versus 4.8). CONCLUSIONS: Stimulant-induced enhancement of sexual desire could be one mechanism by which stimulant drugs such as cocaine and methamphetamine increase the risk for HIV transmission even when they are not injected.
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“They are associated with increased risk-taking and delay discounting (Berry et al., 2022;Skryabin et al., 2020;Volkow et al., 2007).”
From A motivation model of sex addiction – Relevance to the controversy over the concept (2022) · cites this paper as Volkow et al., 2007
Citations
Cites
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A review of the clinical pharmacology of methamphetamine
Cruickshank, C., & Dyer, K. R. (2009) · Addiction · doi:10.1111/j.1360-0443.2009.02564.x · Cited by 802
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Metadata
- Authors
- Volkow, N. D., Wang, G.-J., Fowler, J. S., Telang, F., Jayne, M., & Wong, C.
- Affiliations
- National Institute on Drug Abuse (US)
- Venue
- American Journal of Psychiatry
- Published
- 2007-01
- Volume
- 164
- Issue
- 1
- Pages
- 157-160
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2158876851
- Cited by
- 151
- References
- 16
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 4 · 2023: 1 · 2022: 9 · 2021: 6 · 2020: 7 · 2019: 7 · 2018: 12 · 2017: 7 · 2016: 13 · 2015: 5 · 2014: 9 · 2013: 8 · 2012: 6
- FWCI
- 9.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- Topics
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- HIV transmission, sexual desire, stimulant abuse, cocaine, methylphenidate, methamphetamine, sexual risk behavior, HIV risk factors
- MeSH terms
- Administration, Oral, Adult, Central Nervous System Stimulants, Dose-Response Relationship, Drug, Female, Humans, Injections, Intravenous, Libido, Male, Methamphetamine, Methylphenidate, Placebos, Risk-Taking, Sexual Behavior, HIV Infections, Comorbidity, Cocaine-Related Disorders
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