The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Depression in Schizophrenia: Perspective in the Era of “Atypical” Antipsychotic Agents
Abstract
OBJECTIVE: The author sought to provide a contemporary understanding of depression in schizophrenia and promote a treatment orientation. METHOD: Computer and library-based resources were used to review the literature on depression in schizophrenia. RESULTS: Despite multiple definitions of "depression," a substantial rate of depression has consistently been found in patients with schizophrenia. A differential diagnosis can be used to advance the understanding and treatment of depression in schizophrenia, and changes in response to the advent of atypical antipsychotic agents can be understood in the context of this differential diagnosis paradigm. CONCLUSIONS: Depression is an important co-occurring syndrome in schizophrenia. In at least some schizophrenic patients, the stress-vulnerability model has potential as an integrating concept concerning the relationship between depression and psychosis.
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Citations
Cites
The Positive and Negative Syndrome Scale (PANSS) for schizophrenia.
Kay, S. R., Fiszbein, A., & Opler, L. A. (1987) · Schizophrenia Bulletin · doi:10.1093/schbul/13.2.261 · Cited by 21,378
A new depression scale designed to be sensitive to change
Montgomery, S. A., & Åsberg, M. (1979) · British Journal of Psychiatry · doi:10.1192/bjp.134.4.382 · Cited by 13,962
Cited by
Psychiatric Comorbidities and Schizophrenia
Buckley, P. F., Miller, B. J., Lehrer, D. S., & Castle, D. J. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbn135 · Cited by 1,121
Galletly, C., Castle, D., Dark, F., Humberstone, V., Jablensky, A., Killackey, E., Kulkarni, J., McGorry, P., Nielssen, O., & Tran, N. (2016) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867416641195 · Cited by 877
Malhi, G. S., Bassett, D., Boyce, P., Bryant, R., Fitzgerald, P. B., Fritz, K., Hopwood, M., Lyndon, B., Mulder, R., Murray, G., et al. (2015) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867415617657 · Cited by 842
“Finally, in patients who are relatively clinically stable, it is possible that the onset of depressive symptoms is a prodrome of psychotic relapse (Siris, 2000).”
BackgroundInfluentialResearch Domain Criteria: cognitive systems, neural circuits, and dimensions of behavior
Morris, S. E., & Cuthbert, B. N. (2012) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2012.14.1/smorris · Cited by 638
Miyamoto, S., Miyake, N., Jarskog, L. F., Fleischhacker, W. W., & Lieberman, J. A. (2012) · Molecular Psychiatry · doi:10.1038/mp.2012.47 · Cited by 573
Metadata
- Authors
- Siris, S. G.
- Venue
- American Journal of Psychiatry
- Published
- 2000-09-01
- Volume
- 157
- Issue
- 9
- Pages
- 1379-1389
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W1999320625
- Cited by
- 427
- References
- 2
- FWCI
- 8.47
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Depression in Schizophrenia: Perspective in the Era of “Atypical” Antipsychotic Agents. https://app.cochat.ai/papers/10.1176/appi.ajp.157.9.1379
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- Siris, S. G. (2000). Depression in Schizophrenia: Perspective in the Era of “Atypical” Antipsychotic Agents. American Journal of Psychiatry. https://doi.org/10.1176/appi.ajp.157.9.1379
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
