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Cited by 201

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Impairment of Executive Function But Not Memory in First-Degree Relatives of Patients With Bipolar I Disorder and in Euthymic Patients With Unipolar Depression

Clark, Luke, Sarna, Antonina, Goodwin, Guy M.·2005·American Journal of Psychiatry

Abstract

OBJECTIVE: The authors' goal was to characterize cognitive flexibility and verbal learning in relatives of patients with bipolar disorder and in euthymic patients with recurrent major depression. METHOD: The intradimensional/extradimensional shift task and California Verbal Learning Test were administered to 27 first-degree relatives of probands with bipolar I disorder, 15 euthymic outpatients with recurrent unipolar depression, and 47 healthy comparison subjects. RESULTS: The relatives of patients with bipolar I disorder and the euthymic patients with unipolar depression were more likely to fail the intradimensional/extradimensional shift task than the healthy comparison subjects. The impairments at the extradimensional shift stage were pronounced. Verbal learning, delayed recall, and recognition were unimpaired in all groups. CONCLUSIONS: Attentional set shifting may represent an endophenotype in mood disorder, related to underlying vulnerability rather than the actual disease phenotype.

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Crossref · 10.1176/appi.ajp.162.10.1980

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Metadata

Authors
Clark, L., Sarna, A., & Goodwin, G. M.
Venue
American Journal of Psychiatry
Published
2005-10-01
Volume
162
Issue
10
Pages
1980-1982
ISSN
  • 0002-953X (ISSN-L)
  • 1535-7228
OpenAlex
W2150096817
Cited by
201
References
6
FWCI
6.78
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Impairment of Executive Function But Not Memory in First-Degree Relatives of Patients With Bipolar I Disorder and in Euthymic Patients With Unipolar Depression. https://app.cochat.ai/papers/10.1176/appi.ajp.162.10.1980
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Clark, L., Sarna, A., & Goodwin, G. M. (2005). Impairment of Executive Function But Not Memory in First-Degree Relatives of Patients With Bipolar I Disorder and in Euthymic Patients With Unipolar Depression. American Journal of Psychiatry. https://doi.org/10.1176/appi.ajp.162.10.1980

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