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Cited by 552

The DOI matches its Crossref record; 119 of the 119 references it cites were found in a registry or an index.

Co-Occurring Mental and Substance Use Disorders: The Neurobiological Effects of Chronic Stress

Brady, Kathleen T., Sinha, Rajita·2005·American Journal of Psychiatry

Abstract

The high rate of co-occurrence of substance use disorders and other psychiatric disorders is well established. The population of people with co-occurring disorders is heterogeneous, and the prevalence of comorbidity differs by diagnostic group. One of the overarching issues in the area of comorbidity is the nature of the connection between psychiatric disorders and substance use disorders. The rapid development of technical advances in the neurosciences has led to a better understanding of the molecular biology, neurotransmitter systems, and neural circuitry involved in mental illness and substance use disorders. The authors discuss the neurobiological interface between substance use disorders and other psychiatric disorders with an emphasis on emerging data concerning four psychiatric disorders that commonly co-occur with substance use disorders: depression/mood disorders, posttraumatic stress disorder, attention deficit hyperactivity disorder, and schizophrenia. Better understanding of the connection between substance use disorders and psychiatric disorders could have a profound effect on prevention and treatment.

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Crossref · 10.1176/appi.ajp.162.8.1483

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Metadata

Authors
Brady, K. T., & Sinha, R.
Venue
American Journal of Psychiatry
Published
2005-08-01
Volume
162
Issue
8
Pages
1483-1493
ISSN
  • 0002-953X (ISSN-L)
  • 1535-7228
OpenAlex
W2135141310
Cited by
552
References
119
FWCI
14.18
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Co-Occurring Mental and Substance Use Disorders: The Neurobiological Effects of Chronic Stress. https://app.cochat.ai/papers/10.1176/appi.ajp.162.8.1483
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Brady, K. T., & Sinha, R. (2005). Co-Occurring Mental and Substance Use Disorders: The Neurobiological Effects of Chronic Stress. American Journal of Psychiatry. https://doi.org/10.1176/appi.ajp.162.8.1483

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.