A Double-Blind Randomized Controlled Trial of N -Acetylcysteine in Cannabis-Dependent Adolescents

Gray, Kevin M., Carpenter, Matthew J., Baker, Nathaniel L., DeSantis, Stacia M., Kryway, Elisabeth, Hartwell, Karen J., McRae-Clark, Aimee L., Brady, Kathleen T.·2012·American Journal of Psychiatry
DOI 10.1176/appi.ajp.2012.12010055

Cited by (305)

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  67. Evidence-Based Treatments for Adolescent Substance Use Disorders
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  68. Literaturverzeichnis zu Voderholzer/Hohagen (Hrsg.): Therapie psychischer Erkrankungen, 14. Auflage
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  70. Literaturverzeichnis zu Voderholzer, Hohagen (Hrsg.): Therapie psychischer Erkrankungen, 10. Auflage
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  82. Substanzgebundener Missbrauch und Abhängigkeit im Kindes- und Jugendalter
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  88. Comorbid Cannabis Use and Mood Disorders Among Adolescents
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  92. Chapter 9. Youth Cannabis Use
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  93. Chapter 4. Cannabis: A Natural Dilemma
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  94. Chapter 8. Treatment of Marijuana Addiction
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  95. Chapter 2. Relationship Between Substance Use Disorders and Psychiatric Comorbidity
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  96. Chapter 11. Integrative Medicine Approaches to Addiction Treatment
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