Bipolar Disorder, Schizophrenia, and Metabolic Syndrome
Abstract
There is a lack of data allowing direct comparison of MetS rates between individuals with schizophrenia and bipolar disorder. Among articles screened for suitability for inclusion in meta-analysis, 11 provided data on metabolic syndrome prevalence rates of 3,888 unique participants: 1,572 with bipolar disorder and 2,316 with schizophrenia. Individuals with metabolic syndrome were 705 among bipolar patients and 890 among schizophrenia patients. The random-effect pooled odds ratio (bipolar disorder vs. schizophrenia) was 1.01 (95%CI: 0.82–1.24; p=0.93), with low heterogeneity across the studies. Additional subgroup analyses did not reveal any significant difference. Our meta-analytic findings highlighted that individuals with bipolar disorder and schizophrenia have comparable chances of having metabolic syndrome.
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A brief meta-analytic report comparing metabolic syndrome frequencies in patients with schizophrenia and bipolar disorder found that these populations are at similar risk.
“A brief meta-analytic report comparing MetS frequencies in patients with schizophrenia and bipolar disorder found that these populations are at similar risk (25).”
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References 12 · Cited by 35
- Authors
- Bartoli, F., Carrà, G., Crocamo, C., Carretta, D., & Clerici, M.
- Affiliations
- Azienda Ospedaliera San Gerardo (IT)
- Venue
- American Journal of Psychiatry
- Published
- 2013-08
- Volume
- 170
- Issue
- 8
- Pages
- 927-928
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2113871424
- Cited by
- 35
- References
- 12
- Citations by year
- 2026: 1 · 2024: 1 · 2022: 6 · 2021: 1 · 2020: 3 · 2018: 4 · 2017: 7 · 2016: 2 · 2015: 6 · 2014: 2 · 2013: 2
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- BOA (University of Milano-Bicocca) (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- bipolar disorder, schizophrenia, metabolic syndrome, prevalence, psychiatric comorbidity, metabolic risk
- MeSH terms
- Bipolar Disorder, Female, Humans, Male, Antipsychotic Agents, Metabolic Syndrome
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