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Cited by 27Heart Failure Treatment and ManagementCardiovascular and exercise physiologyTraumatic Brain Injury and Neurovascular Disturbances

The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.

Effect of enalapril maleate on cerebral blood flow in patients with chronic heart failure.

Kamishirado, Hirotoshi, Inoue, Teruo, Fujito, Tsuneo, Kase, Makoto, Shimizu, Minoru, Sakai, Yoshihiko, Takayanagi, Kan, Morooka, Shigenori, Natsui, Satoshi, Kamishirado, Hirotoshi·1997·Angiology
DOI 10.1177/000331979704800806
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Abstract

The effect of enalapril on cerebral blood flow (CBF) was studied in 11 patients with chronic heart failure (NYHA II or III, dilated cardiomyopathy in 6 and old myocardial infarction in 5). CBF was evaluated by analyzing the Patlak-Plot curve obtained from radionuclide angiography with technetium-99m hexamethylpropylene amine oxime (99mTC-HM-PAO). Cardiac index (CI) and stroke volume (SV) were simultaneously measured by impedance cardiography. These measurements were performed before and at four weeks after daily administration of 5 mg enalapril. The stroke volume, cardiac index, and heart rate were not significantly changed after four weeks of enalapril administration. However, CBF was increased by 6.5% from 36.72 +/- 4.66 to 39.13 +/- 5.65 mL/100g/min (P < 0.05). These results suggest that enalapril increased cerebral blood flow, which was not related to increased cardiac output in congestive heart failure. Patlak-Plot analysis of radionuclide angiography using 99mTC-HM-PAO may be available for quantitative assessment of brain perfusion.

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Crossref · 10.1177/000331979704800806

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14 of 14 references verified0 citation errors · 0 not checkable

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  • When modeling the response to antihypertensive therapies, the influence of angiotensin II on cardiac muscle must be taken into account to simulate decrease in blood pressure without increasing heart rate.

    “Thus, when modeling the response to antihypertensive therapies, the influence of angiotensin II on cardiac muscle must be taken into account to simulate decrease in blood pressure without increasing heart rate, which, for instance, is the standard effect of such RAAS inhibitors as aliskiren, losartan, and enalapril (Konstam et al., 1993; Kamishirado et al., 1997; González-Abraldes et al., 2001;”

    From Thoroughly Calibrated Modular Agent-Based Model of the Human Cardiovascular and Renal Systems for Blood Pressure Regulation in Health and Disease (2021) · cites this paper as Kamishirado et al., 1997

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Metadata

Authors
Kamishirado, H., Inoue, T., Fujito, T., Kase, M., Shimizu, M., Sakai, Y., Takayanagi, K., Morooka, S., Natsui, S., & Kamishirado, H.
ORCID
Venue
Angiology
Publisher
SAGE Publications
Published
1997-08
Volume
48
Issue
8
Pages
707-713
ISSN
  • 0003-3197 (ISSN-L)
  • 1940-1574
DOI
10.1177/000331979704800806
OpenAlex
W2057322285
Cited by
27
References
14
Citations by year
2024: 1 · 2021: 2 · 2020: 1 · 2017: 1 · 2015: 1 · 2014: 5 · 2012: 1
FWCI
0.97
Type
journal article
Language
en
Open access
closed
Licence
journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations
  • Angiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
  • Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury and Neurovascular Disturbances
Keywords
enalapril, cerebral blood flow, chronic heart failure, dilated cardiomyopathy, myocardial infarction, ACE inhibitors, cerebral perfusion, stroke volume, cardiac index
MeSH terms
Aged, Angiotensin-Converting Enzyme Inhibitors, Blood Flow Velocity, Cardiac Output, Cardiomyopathy, Dilated, Cerebrovascular Circulation, Chronic Disease, Enalapril, Female, Heart Failure, Heart Rate, Humans, Male, Middle Aged, Oximes, Radionuclide Angiography, Stroke Volume, Organotechnetium Compounds, Technetium Tc 99m Exametazime

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