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Cited by 192

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Stem Cells from Deciduous Tooth Repair Mandibular Defect in Swine

Open access
Zheng, Y., Liu, Y., Zhang, C.M., Zhang, H.Y., Li, W.H., Shi, S., Le, A.D., Wang, S.L.·2009·Journal of Dental Research

Abstract

Stem cells from human exfoliated deciduous teeth have been identified as a new post-natal stem cell population with multipotential differentiation capabilities, including regeneration of mineralized tissues in vivo. To examine the efficacy of utilizing these stem cells in regenerating orofacial bone defects, we isolated stem cells from miniature pig deciduous teeth and engrafted the critical-size bone defects generated in swine mandible models. Our results indicated that stem cells from miniature pig deciduous teeth, an autologous and easily accessible stem cell source, were able to engraft and regenerate bone to repair critical-size mandibular defects at 6 months post-surgical reconstruction. This pre-clinical study in a large-animal model, specifically swine, allows for testing of a stem cells/scaffold construct in the restoration of orofacial skeletal defects and provides rapid translation of stem-cell-based therapy in orofacial reconstruction in human clinical trials.

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Metadata

Authors
Zheng, Y., Liu, Y., Zhang, C. M., Zhang, H. Y., Li, W. H., Shi, S., Le, A. D., & Wang, S. L.
Venue
Journal of Dental Research
Published
2009-03
Volume
88
Issue
3
Pages
249-254
ISSN
  • 0022-0345 (ISSN-L)
  • 1544-0591
OpenAlex
W2055400697
Cited by
192
References
1
FWCI
6.99
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Stem Cells from Deciduous Tooth Repair Mandibular Defect in Swine. https://app.cochat.ai/papers/10.1177/0022034509333804
The paper
Zheng, Y., Liu, Y., Zhang, C. M., Zhang, H. Y., Li, W. H., Shi, S., Le, A. D., & Wang, S. L. (2009). Stem Cells from Deciduous Tooth Repair Mandibular Defect in Swine. Journal of Dental Research. https://doi.org/10.1177/0022034509333804

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.