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Efficacy of Silver Diamine Fluoride for Arresting Caries Treatment
Abstract
Arresting Caries Treatment (ACT) has been proposed to manage untreated dental caries in children. This prospective randomized clinical trial investigated the caries-arresting effectiveness of a single spot application of: (1) 38% silver diamine fluoride (SDF) with tannic acid as a reducing agent; (2) 38% SDF alone; (3) 12% SDF alone; and (4) no SDF application in primary teeth of 976 Nepalese schoolchildren. The a priori null hypothesis was that the different treatments have no effect in arresting active cavitated caries. Only the single application of 38% SDF with or without tannic acid was effective in arresting caries after 6 months (4.5 and 4.2 mean number of arrested surfaces; p < 0.001), after 1 year (4.1 and 3.4; p < 0.001), and after 2 years (2.2 and 2.1; p < 0.01). Tannic acid conferred no additional benefit. ACT with 38% SDF provides an alternative when restorative treatment for primary teeth is not an option.
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Cited by
Minimal intervention dentistry for managing dental caries – a review
Frencken, J. E., Peters, M. C., Manton, D. J., Leal, S. C., Gordan, V. V., & Eden, E. (2012) · International Dental Journal · doi:10.1111/idj.12007 · Cited by 531
UCSF Protocol for Caries Arrest Using Silver Diamine Fluoride: Rationale, Indications and Consent
Horst, J. A., Ellenikiotis, H., & Milgrom, P. L. (2016) · Journal of the California Dental Association · doi:10.1080/19424396.2016.12220962 · Cited by 426
Topical fluoride for caries prevention
Weyant, R. J., Tracy, S. L., Anselmo, T. (., Beltrán-Aguilar, E. D., Donly, K. J., Frese, W. A., Hujoel, P. P., Iafolla, T., Kohn, W., Kumar, J., et al. (2013) · The Journal of the American Dental Association · doi:10.14219/jada.archive.2013.0057 · Cited by 357
Evidence-based clinical practice guideline on nonrestorative treatments for carious lesions
Slayton, R. L., Urquhart, O., Araujo, M. W. B., Fontana, M., Guzmán-Armstrong, S., Nascimento, M. M., Nový, B. B., Tinanoff, N., Weyant, R. J., Wolff, M. S., et al. (2018) · The Journal of the American Dental Association · doi:10.1016/j.adaj.2018.07.002 · Cited by 317
Evidence-based dentistry update on silver diamine fluoride
Crystal, Y. O., & Niederman, R. (2019) · Dental Clinics of North America · doi:10.1016/j.cden.2018.08.011 · Cited by 253
Metadata
- Authors
- Yee, R., Holmgren, C., Mulder, J., Lama, D., Walker, D., & van Palenstein Helderman, W.
- Venue
- Journal of Dental Research
- Publisher
- SAGE Publications
- Published
- 2009-07
- Volume
- 88
- Issue
- 7
- Pages
- 644-647
- ISSN
- 0022-0345 (ISSN-L)
- 1544-0591
- OpenAlex
- W2122622727
- Cited by
- 289
- References
- 0
- FWCI
- 8.28
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yee, R., Holmgren, C., Mulder, J., Lama, D., Walker, D., & van Palenstein Helderman, W. (2009). Efficacy of Silver Diamine Fluoride for Arresting Caries Treatment. Journal of Dental Research. https://doi.org/10.1177/0022034509338671
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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