The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Effect of a Calcium-silicate-based Restorative Cement on Pulp Repair
Abstract
In cases of pulp injury, capping materials are used to enhance tertiary dentin formation; Ca(OH)2 and MTA are the current gold standards. The aim of this study was to evaluate the capacity of a new calcium-silicate-based restorative cement to induce pulp healing in a rat pulp injury model. For that purpose, cavities with mechanical pulp exposure were prepared on maxillary first molars of 27 six-week-old male rats, and damaged pulps were capped with either the new calcium-silicate-based restorative cement (Biodentine), MTA, or Ca(OH)2. Cavities were sealed with glass-ionomer cement, and the repair process was assessed at several time-points. At day 7, our results showed that both the evaluated cement and MTA induced cell proliferation and formation of mineralization foci, which were strongly positive for osteopontin. At longer time-points, we observed the formation of a homogeneous dentin bridge at the injury site, secreted by cells displaying an odontoblastic phenotype. In contrast, the reparative tissue induced by Ca(OH)2 showed porous organization, suggesting a reparative process different from those induced by calcium silicate cements. Analysis of these data suggests that the evaluated cement can be used for direct pulp-capping.
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Cites
Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo
Gronthos, S., Mankani, M., Brahim, J., Robey, P. G., & Shi, S. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.240309797 · Cited by 4,570
The effects of surgical exposures of dental pulps in germ-free and conventional laboratory rats
Kakehashi, S., Stanley, H. R., & Fitzgerald, R. J. (1965) · Oral Surgery, Oral Medicine, Oral Pathology · doi:10.1016/0030-4220(65)90166-0 · Cited by 2,330
Physical and chemical properties of a new root-end filling material
TORABINEJAD, M., HONG, C., MCDONALD, F., & PITTFORD, T. (1995) · Journal of Endodontics · doi:10.1016/s0099-2399(06)80967-2 · Cited by 1,493
Sealing ability of a mineral trioxide aggregate when used as a root end filling material
Torabinejad, M., Watson, T. F., & Pitt Ford, T. R. (1993) · Journal of Endodontics · doi:10.1016/s0099-2399(06)80271-2 · Cited by 1,158
Schröder, U. (1985) · Journal of Dental Research · doi:10.1177/002203458506400407 · Cited by 566
Using Mineral Trioxide Aggregate as a Pulp-Capping Material
FORD, T. R. P., TORABINEJAD, M., ABEDI, H. R., BAKLAND, L. K., & KARIYAWASAM, S. P. (1996) · The Journal of the American Dental Association · doi:10.14219/jada.archive.1996.0058 · Cited by 546
Goldberg, M., & Smith, A. J. (2004) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/154411130401500103 · Cited by 535
BiodentineTM induces TGF‐β 1 release from human pulp cells and early dental pulp mineralization
Laurent, P., Camps, J., & About, I. (2012) · International Endodontic Journal · doi:10.1111/j.1365-2591.2011.01995.x · Cited by 422
Characterization of hydration products of mineral trioxide aggregate
Camilleri, J. (2008) · International Endodontic Journal · doi:10.1111/j.1365-2591.2007.01370.x · Cited by 411
Dual origin of mesenchymal stem cells contributing to organ growth and repair
Feng, J., Mantesso, A., De Bari, C., Nishiyama, A., & Sharpe, P. T. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015449108 · Cited by 410
Cited by
Response of Human Dental Pulp Capped with Biodentine and Mineral Trioxide Aggregate
Nowicka, A., Lipski, M., Parafiniuk, M., Sporniak-Tutak, K., Lichota, D., Kosierkiewicz, A., Kaczmarek, W., & Buczkowska-Radlińska, J. (2013) · Journal of Endodontics · doi:10.1016/j.joen.2013.01.005 · Cited by 490
A Review on Biodentine, a Contemporary Dentine Replacement and Repair Material
Malkondu, Ö., Kazandağ, M. K., & Kazazoğlu, E. (2014) · BioMed Research International · doi:10.1155/2014/160951 · Cited by 384
Calcium silicate‐based cements: composition, properties, and clinical applications
Dawood, A. E., Parashos, P., Wong, R. H. K., Reynolds, E. C., & Manton, D. J. (2017) · Journal of Investigative and Clinical Dentistry · doi:10.1111/jicd.12195 · Cited by 255
Metadata
- Authors
- Tran, X. V., Gorin, C., Willig, C., Baroukh, B., Pellat, B., Decup, F., Opsahl Vital, S., Chaussain, C., & Boukpessi, T.
- Venue
- Journal of Dental Research
- Publisher
- SAGE Publications
- Published
- 2012-09-13
- Volume
- 91
- Issue
- 12
- Pages
- 1166-1171
- ISSN
- 0022-0345 (ISSN-L)
- 1544-0591
- OpenAlex
- W2001704880
- Cited by
- 277
- References
- 25
- FWCI
- 16.44
- Type
- journal article
- Language
- en
- Open access
- closed
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- Tran, X. V., Gorin, C., Willig, C., Baroukh, B., Pellat, B., Decup, F., Opsahl Vital, S., Chaussain, C., & Boukpessi, T. (2012). Effect of a Calcium-silicate-based Restorative Cement on Pulp Repair. Journal of Dental Research. https://doi.org/10.1177/0022034512460833
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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