Variations in the Crystalline Components of Human Dental Calculus: I. Crystallographic and Spectroscopic Methods of Analysis
Abstract
The diffractometric method has more advantages than the camera technique for X-ray diffraction analysis of the crystalline components of human dental calculus. With the use of this crystallographic method and infrared absorption techniques, it was found that the magnesium content of human dental calculus is the result of partial substitution of magnesium for calcium in whitlockite, and that the carbonate content is the result of substitution in apatite.
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Dental calculus includes a range of calcium phosphate minerals, including apatite, whitlockite, tricalcium phosphate, and octacalcium phosphate.
“Dental calculus includes a range of calcium phosphate minerals, including apatite, Whitlockite, tricalcium phosphate, and octacalcium phosphate [92–95].”
From A Review of Phosphate Mineral Nucleation in Biology and Geobiology (2013) · cites this paper as [94]
Cites
Formation and Inhibition of Dental Calculus
Schroeder, H. E., & Shanley, D. (1969) · Journal of Periodontology-Periodontics · doi:10.1902/jop.1969.40.11.643 · Cited by 209 · see citing works
Pathological calcifications associated with uremia
LeGeros, R. Z., Contiguglia, S. R., & Alfrey, A. C. (1973) · Calcified Tissue International · doi:10.1007/bf02015408 · Cited by 84 · see citing works
Whitlockite: A new calcium phosphate, Ca3(PO4)2
Frondel, C. (1941) · American Mineralogist · Cited by 78 · see citing works
Changes in crystal types of low solubility calcium phosphates in the presence of accompanying ions
Newesely, H. (1961) · Archives of Oral Biology · doi:10.1016/0003-9969(61)90032-2 · Cited by 76 · see citing works
Stages of calcium phosphate crystallisation during calculus formation
Schroeder, H. E., & Bambauer, H. U. (1966) · Archives of Oral Biology · doi:10.1016/0003-9969(66)90112-9 · Cited by 69 · see citing works
Brushite crystals grown by diffusion in silica gel and in solution
LeGeros, R. Z., & LeGeros, J. P. (1972) · Journal of Crystal Growth · doi:10.1016/0022-0248(72)90284-9 · Cited by 66 · see citing works
Grøn, P., van Campen, G. J., & Lindstrom, I. (1967) · Archives of Oral Biology · doi:10.1016/0003-9969(67)90105-7 · Cited by 58 · see citing works
Magnesian Whitlockite, a Major Constituent of Dental Calculus
Jensen, A. T., & Rowles, S. L. (1957) · Acta Odontologica Scandinavica · doi:10.3109/00016355709041096 · Cited by 58 · see citing works
Crystallography of Dental Calculus and the Precipitation of Certain Calcium Phosphates
Jensen, A. T., & Danø, M. (1954) · Journal of Dental Research · doi:10.1177/00220345540330060201 · Cited by 58 · see citing works
Chemical Investigation of Salivary Calculus
Glock, G. E., & Murray, M. M. (1938) · Journal of Dental Research · doi:10.1177/00220345380170040101 · Cited by 44 · see citing works
Tetracalcium hydrogen triphosphate trihydrate, a constituent of dental calculus
Jensen, A. T., & Hansen, K. G. (1957) · Cellular and Molecular Life Sciences · doi:10.1007/bf02296810 · Cited by 27 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Eliaz, N., & Metoki, N. (2017) · Materials · doi:10.3390/ma10040334 · Cited by 1,092 · see citing works
Bioactive calcium phosphate materials and applications in bone regeneration
Jeong, J., Kim, J. H., Shim, J. H., Hwang, N. S.-Y., & Heo, C. Y. (2019) · Biomaterials Research · doi:10.1186/s40824-018-0149-3 · Cited by 1,066 · see citing works
Ionic substitutions in calcium phosphates synthesized at low temperature
Boanini, E., Gazzano, M., & Bigi, A. (2009) · Acta Biomaterialia · doi:10.1016/j.actbio.2009.12.041 · Cited by 828 · see citing works
Calcium Orthophosphates in Nature, Biology and Medicine
Dorozhkin, S. V. (2009) · Materials · doi:10.3390/ma2020399 · Cited by 840 · see citing works
Apatites in biological systems
Zapanta LeGeros, R. (1981) · Progress in Crystal Growth and Characterization · doi:10.1016/0146-3535(81)90046-0 · Cited by 622 · see citing works
Dorozhkin, S. V. (2007) · Journal of Materials Science · doi:10.1007/s10853-006-1467-8 · Cited by 574 · see citing works
Krämer, J., Kang, R., Grimm, L., Cola, L. D., Picchetti, P., & Biedermann, F. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00746 · Cited by 455 · see citing works
Dorozhkin, S. V. (2011) · Biomatter · doi:10.4161/biom.18790 · Cited by 371 · see citing works
Phosphate Minerals in Human Tissues
LeGeros, R. Z., & LeGeros, J. P. (1984) · Springer eBooks · doi:10.1007/978-3-642-61736-2_12 · Cited by 251 · see citing works
Daculsi, G., Bouler, J., & LeGeros, R. Z. (1997) · International review of cytology · doi:10.1016/s0074-7696(08)62360-8 · Cited by 189 · see citing works
Preparation of octacalcium phosphate (OCP): A direct fast method
LeGeros, R. Z. (1985) · Calcified Tissue International · doi:10.1007/bf02554841 · Cited by 172 · see citing works
Abbona, F., Madsen, H. E. L., & BOISTELLE, R. (1986) · Journal of Crystal Growth · doi:10.1016/0022-0248(86)90205-8 · Cited by 146 · see citing works
Kannan, S., Goetz‐Neunhoeffer, F., Neubauer, J., Pina, S., Torres, P. M. C., & Ferreira, J. M. F. (2009) · Acta Biomaterialia · doi:10.1016/j.actbio.2009.08.009 · Cited by 139 · see citing works
Chemical and Crystallographic Events in the Caries Process
LeGeros, R. Z. (1990) · Journal of Dental Research · doi:10.1177/00220345900690s113 · Cited by 115 · see citing works
Possible Physico-Chemical Processes in Human Dentin Caries
Daculsi, G., LeGeros, R. Z., Jean, A., & Kerebel, B. (1987) · Journal of Dental Research · doi:10.1177/00220345870660081401 · Cited by 109 · see citing works
Dynamics of Biomineral Formation at the Near-Molecular Level
Qiu, S., & Orme, C. A. (2008) · Chemical Reviews · doi:10.1021/cr800322u · Cited by 108 · see citing works
Asymmetrische Photochemie und Photochirogenese
Griesbeck, A. G., & Meierhenrich, U. J. (2002) · Angewandte Chemie · doi:10.1002/1521-3757(20020902)114:17 · Cited by 29 · see citing works
A Review of Phosphate Mineral Nucleation in Biology and Geobiology
Omelon, S., Ariganello, M., Bonucci, E., Grynpas, M., & Nanci, A. (2013) · Calcified Tissue International · doi:10.1007/s00223-013-9784-9 · Cited by 84 · see citing works
Ishikawa, K., Miyamoto, Y., Takechi, M., Toh, T., Kon, M., Nagayama, M., & Asaoka, K. (1997) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(19970905)36:3 · Cited by 116 · see citing works
Crystallization of calcium and magnesium phosphates from solutions of low concentration
Abbona, F., & Franchini-Angela, M. (1990) · Journal of Crystal Growth · doi:10.1016/0022-0248(90)90009-a · Cited by 74 · see citing works
Biocompatible nanocrystalline octacalcium phosphate thin films obtained by pulsed laser deposition
Socol, G., Torricelli, P., Bracci, B., Iliescu, M., Miroiu, F. M., Bigi, A., Werckmann, J., & Mihailescu, I. N. (2003) · Biomaterials · doi:10.1016/j.biomaterials.2003.09.044 · Cited by 72 · see citing works
The effects of magnesium and fluoride on the hydrolysis of octacalcium phosphate
Tung, M. S., Tomazic, B. B., & Brown, W. E. (1992) · Archives of Oral Biology · doi:10.1016/0003-9969(92)90142-u · Cited by 68 · see citing works
The crystal chemistry of submandibular and parotid salivary gland stones
Burstein, L. S., Boskey, A. L., Tannenbaum, P. J., Posner, A. S., & Mandel, I. D. (1979) · Journal of Oral Pathology and Medicine · doi:10.1111/j.1600-0714.1979.tb01830.x · Cited by 60 · see citing works
Cheng, P. (1987) · Calcified Tissue International · doi:10.1007/bf02556696 · Cited by 58 · see citing works
Nikolenko, N. V., Vasylenko, K. V., Myrhorodska-Terentieva, V. D., Kostyniuk, A., & Likozar, B. (2020) · Processes · doi:10.3390/pr8091009 · Cited by 55 · see citing works
Theoretical Defect Energetics in Calcium Phosphate Bioceramics
Matsunaga, K. (2009) · Journal of the American Ceramic Society · doi:10.1111/j.1551-2916.2009.03485.x · Cited by 55 · see citing works
Anti-Calculus and Whitening Toothpastes
van Loveren, C., & Duckworth, R. M. (2013) · Monographs in oral science · doi:10.1159/000350698 · Cited by 44 · see citing works
Gopi, D., Murugan, N., Ramya, S., & Kavitha, L. (2014) · Journal of Materials Chemistry B · doi:10.1039/c4tb00960f · Cited by 43 · see citing works
RetractedEffect of sodium polyacrylate on the hydrolysis of octacalcium phosphate
Bigi, A., Boanini, E., Falini, G., Panzavolta, S., & Roveri, N. (2000) · Journal of Inorganic Biochemistry · doi:10.1016/s0162-0134(00)00015-5 · Cited by 41 · see citing works
Thermal conversion of octacalcium phosphate into hydroxyapatite
Bigi, A., Ripamonti, A., Cojazzi, G., Gazzano, M., & Roveri, N. (1990) · Journal of Inorganic Biochemistry · doi:10.1016/0162-0134(90)80063-4 · Cited by 38 · see citing works
The study of human dentine with secondary ion microscopy and electron diffraction
Lefèvre, R.-A., Frank, R. M., & Voegel, J. (1975) · Calcified Tissue International · doi:10.1007/bf02564008 · Cited by 37 · see citing works
Cristallographic behaviour of fluoridated hydroxyapatites containing Mg2+ and CO2−3 ions
Okazaki, M. (1991) · Biomaterials · doi:10.1016/0142-9612(91)90070-q · Cited by 36 · see citing works
Effect of foreign ions on the conversion of brushite and octacalcium phosphate into hydroxyapatite
Bigi, A., Gazzano, M., Ripamonti, A., & Roveri, N. (1988) · Journal of Inorganic Biochemistry · doi:10.1016/0162-0134(88)85004-9 · Cited by 33 · see citing works
Okazaki, M. (1995) · Biomaterials · doi:10.1016/0142-9612(95)99698-l · Cited by 32 · see citing works
Cellular Responses to Whitlockite
Ryan, L. M., Cheung, H. S., LeGeros, R. Z., Kurup, I. V., Toth, J. M., Westfall, P. R., & McCarthy, G. (1999) · Calcified Tissue International · doi:10.1007/s002239900716 · Cited by 30 · see citing works
Ultrastructural study of calculus–enamel and calculus–root interfaces
Rohanizadeh, R., & LeGeros, R. Z. (2005) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2004.07.001 · Cited by 29 · see citing works
Osteoinductive and Osteoconductive Biomaterials
Agrawal, S., & Srivastava, R. (2020) · Springer eBooks · doi:10.1007/978-3-030-34471-9_15 · Cited by 27 · see citing works
Distribution and incorporation of zinc in biological calcium phosphates
Barrea, R. A., Perez, C. A., Ramos, A. Y., Sánchez, H. J., & Grenón, M. S. (2003) · X-Ray Spectrometry · doi:10.1002/xrs.657 · Cited by 27 · see citing works
Computer graphics of hydroxyapatite and β-tricalcium phosphate
Okazaki, M., & Sato, M. H. (1990) · Biomaterials · doi:10.1016/0142-9612(90)90081-z · Cited by 27 · see citing works
In situ luminescence analysis: a new light on monitoring calcium phosphate phase transitions
Terraschke, H., Rothe, M., Tsirigoni, A.-M., Lindenberg, P., Arana, L. R., Heidenreich, N., Bertram, F., & Etter, M. (2017) · Inorganic Chemistry Frontiers · doi:10.1039/c7qi00172j · Cited by 26 · see citing works
Effect of Zn and Mg on the formation of whitlockite in human subgingival calculus
Knuuttila, M. L. E., Lappalainen, R., & Kontturi‐Närhi, V. (1980) · European Journal Of Oral Sciences · doi:10.1111/j.1600-0722.1980.tb01261.x · Cited by 24 · see citing works
Chen, K., & Arai, Y. (2019) · ACS Earth and Space Chemistry · doi:10.1021/acsearthspacechem.9b00089 · Cited by 22 · see citing works
Nesseri, E., Boyatzis, S. C., Boukos, N. K., & Panagiaris, G. (2020) · SN Applied Sciences · doi:10.1007/s42452-020-03547-8 · Cited by 20 · see citing works
Comparative Properties of Deciduous and Permanent (Young and Old) Human Enamel1
LeGeros, R. Z., Piliero, J. A., & Pentel, L. (1983) · Gerodontology · doi:10.1111/j.1741-2358.1983.tb00341.x · Cited by 18 · see citing works
Electron microscopy of octacalcium phosphate in the dental calculus
Kakei, M., Sakae, T., & Yoshikawa, M. (2009) · Journal of Electron Microscopy · doi:10.1093/jmicro/dfp034 · Cited by 18 · see citing works
Model Systems for Formation and Dissolution of Calcium Phosphate Minerals
Orme, C. A., & Giocondi, J. L. (2007) · doi:10.1002/9783527619443.ch32 · Cited by 18 · see citing works
Borah, B. M., Halter, T. J., Xie, B., Henneman, Z. J., Siudzinski, T. R., Harris, S., Elliott, M., & Nancollas, G. H. (2014) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2014.03.029 · Cited by 17 · see citing works
On the physicochemistry of plaque calcification and the phase composition of dental calculus
Driessens, F. C. M., Borggreven, J. M. P. M., Verbeeck, R. M. H., van Dijk, J. W. E., & Feagin, F. F. (1985) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1985.tb00442.x · Cited by 17 · see citing works
McDougall, W. A. (1985) · Archives of Oral Biology · doi:10.1016/0003-9969(85)90080-9 · Cited by 16 · see citing works
Effect of the Calcination Time of Fish Bones in the Synthesis of Hydroxyapatite
Lima, W. M., Weinand, W. R., dos Santos, O. A. A., Paesano, A., & Ortega, F. H. M. (2005) · Materials science forum · doi:10.4028/www.scientific.net/msf.498-499.600 · Cited by 16 · see citing works
The Crystalline Components of Dental Calculus in the Domestic Cat
Clarke, D. E. (1999) · Journal of Veterinary Dentistry · doi:10.1177/089875649901600402 · Cited by 16 · see citing works
Concentrations of Ca, Mg, Mn, Sr and Zn in supra‐ and subgingivalcalculus
Knuuttila, M. L. E., Lappalainen, R., & Kontturi‐Närhi, V. (1979) · European Journal Of Oral Sciences · doi:10.1111/j.1600-0722.1979.tb00672.x · Cited by 16 · see citing works
Solubility Behaviour of Mg‐Containing β‐Ca3 (PO4)2
Verbeeck, R. M. H., Bruyne, P. A. M. D., Driessens, F. C. M., Terpstra, R. A., & Verbeek, F. (1986) · Bulletin des Sociétés Chimiques Belges · doi:10.1002/bscb.19860950519 · Cited by 15 · see citing works
Mróz, W., Bombalska, A., Budner, B., Burdyńska, S., Jedyński, M., Prokopiuk, A., Menaszek, E., Ścisłowska-Czarnecka, A., Niedzielska, A., & Niedzielski, K. R. (2010) · Applied Physics A · doi:10.1007/s00339-010-5926-3 · Cited by 14 · see citing works
Magnesium- and Zinc-Substituted Beta-Tricalcium Phosphates as Potential Bone Substitute Biomaterials
Ito, A., & LeGeros, R. Z. (2008) · Key engineering materials · doi:10.4028/www.scientific.net/kem.377.85 · Cited by 11 · see citing works
Aoba, T., Doi, Y., & Koseki, T. (1979) · Journal of Oral Pathology and Medicine · doi:10.1111/j.1600-0714.1979.tb01838.x · Cited by 10 · see citing works
Transmission electron microscopic observation of heterogeneous fluoridated hydroxyapatites
Tohda, H., Okazaki, M., Yanagisawa, T., & Takahashi, J. (1995) · Biomaterials · doi:10.1016/0142-9612(95)93120-3 · Cited by 10 · see citing works
Aoba, T., & Yagi, T. (1982) · Journal of Oral Pathology and Medicine · doi:10.1111/j.1600-0714.1982.tb00157.x · Cited by 10 · see citing works
Abraham, J., Grenón, M. S., Sánchez, H. J., Valentinuzzi, M. C., & Perez, C. A. (2007) · Spectrochimica Acta Part B Atomic Spectroscopy · doi:10.1016/j.sab.2007.03.008 · Cited by 9 · see citing works
Pino, M., Chrzanowski, W., Fabel, D., Baklar, M. A., Stingelin, N., & Tanner, K. E. (2010) · Advanced Engineering Materials · doi:10.1002/adem.200980088 · Cited by 8 · see citing works
A crystallinity study of dental tissues and tartar by infrared spectroscopy
Abraham, J., Sánchez, H. J., Marcelli, C., Grenón, M. S., Guidi, M. C., & Piccinini, M. (2010) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-010-4430-0 · Cited by 8 · see citing works
Capasso, L., Tota, G., Jones, K. W., & Tuniz, C. (1995) · International Journal of Osteoarchaeology · doi:10.1002/oa.1390050307 · Cited by 8 · see citing works
Thermal decomposition ofLingula shell apatite
Iijima, M., Kamemizu, H., Wakamatsu, N., Goto, T., & Moriwaki, Y. (1991) · Calcified Tissue International · doi:10.1007/bf02565135 · Cited by 7 · see citing works
Studies on the composition of human dental calculus
Molokhia, A., & Nixon, G. S. (1984) · Journal of Radioanalytical and Nuclear Chemistry · doi:10.1007/bf02037141 · Cited by 6 · see citing works
Reaction of Ca2+ and phosphate ester
Okazaki, M., & Hattori, M. (1989) · Biomaterials · doi:10.1016/0142-9612(89)90045-8 · Cited by 6 · see citing works
Okazaki, M. (2004) · Phosphorus Research Bulletin · doi:10.3363/prb1992.17.0_1 · Cited by 6 · see citing works
Inhibition of Formation of Calcium Phosphate Deposits on Teeth and Dental Materials: Recent Advances
Gaffar, A., LeGeros, R. Z., Gambogi, R. J., & Affutto, J. (1995) · Advances in Dental Research · doi:10.1177/08959374950090041201 · Cited by 6 · see citing works
Space-cutting model of hydroxyapatite
Okazaki, M. (1995) · Biomaterials · doi:10.1016/0142-9612(95)91095-g · Cited by 5 · see citing works
BRUSHITE IN FIBROUS DYSPLASIA OF THE JAW BONE
Yamamoto, H., & Sakae, T. (1987) · Acta Pathologica Japonica · doi:10.1111/j.1440-1827.1987.tb02481.x · Cited by 5 · see citing works
Functionalization of octacalcium phosphate for bone replacement
Bigi, A., & Boanini, E. (2019) · Elsevier eBooks · doi:10.1016/b978-0-08-102511-6.00003-0 · Cited by 5 · see citing works
Magnesium in Normal and Pathological Calcifications
LeGeros, R. Z. (1991) · Springer eBooks · doi:10.1007/978-4-431-68132-8_51 · Cited by 5 · see citing works
Growth of octacalcium phosphate and dicalcium phosphate dihydrate crystals in silica gels
Sokolowski, T., & Wiktorowska, B. (1990) · Crystal Research and Technology · doi:10.1002/crat.2170250502 · Cited by 4 · see citing works
Sandin, K., Kloo, L. A., Odselius, R., & Olsson, L. (2009) · PubMed · Cited by 4 · see citing works
Influence of Condensed Phosphates on the Physical Chemistry of Calcium Phosphate Solids
Omelon, S. J., & Habraken, W. J. E. M. (2016) · Springer eBooks · doi:10.1007/978-3-319-41073-9_12 · Cited by 3 · see citing works
Pathologic Mineralization in Humans
Cheng, P. (1991) · Springer eBooks · doi:10.1007/978-4-431-68132-8_40 · Cited by 3 · see citing works
Ceramics and Glass Ceramics for Biomedical Applications
Patra, N., Ramesh, P., Grasso, S., & Boccacini, A. R. (2024) · Composites science and technology · doi:10.1007/978-981-97-3909-7_2 · Cited by 2 · see citing works
Calcium Pyrophosphate Dihydrate Deposition Disease
Katsamenis, O. L., & Bouropoulos, N. (2015) · Elsevier eBooks · doi:10.1016/b978-0-444-63228-9.00014-0 · Cited by 2 · see citing works
Yamaguchi, T., Yamada, I., & Tagaya, M. (2017) · KOBUNSHI RONBUNSHU · doi:10.1295/koron.2017-0054 · Cited by 1 · see citing works
Abraham, J. (2009) · Americanae (AECID Library) · Cited by 1 · see citing works
Bioactive Materials for Bone Tissue Engineering
Alamdari, A. N., Assadzadeh, S., Asadpour, S., Tavakoli, S., Naghavi, M., Khodadadi, A., & Dizaj, S. M. (2020) · Clinical Research in Orthopaedics · doi:10.33309/2639-8885.030101
Interaction of Sodium Polyacrylate with Octacalcium Phosphate
Bigi, A., Boanini, E., Cojazzi, G., Falini, G., Panzavolta, S., & Roveri, N. (2005) · Kluwer Academic Publishers eBooks · doi:10.1007/0-306-46924-3_3
- Authors
- Zapanta Le Geros, R.
- Affiliations
- New York University Dental School, New York, New York 10010, USA
- Venue
- Journal of Dental Research
- Publisher
- SAGE Publications
- Published
- 1974-01
- Volume
- 53
- Issue
- 1
- Pages
- 45-50
- ISSN
- 0022-0345 (ISSN-L)
- 1544-0591
- OpenAlex
- W2135001996
- Cited by
- 82
- References
- 11
- Citations by year
- 2024: 1 · 2022: 1 · 2020: 4 · 2019: 3 · 2017: 3 · 2016: 1 · 2015: 1 · 2014: 2 · 2013: 2
- FWCI
- 0.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Dental Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rheumatology › Bone and Dental Protein Studies
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Physical Sciences › Materials Science › Biomaterials › Calcium Carbonate Crystallization and Inhibition
- Keywords
- dental calculus, whitlockite, apatite, magnesium substitution, calcium substitution, carbonate content, X-ray diffraction, infrared absorption spectroscopy, crystallographic analysis
- MeSH terms
- Apatites, Calcium, Calcium Phosphates, Chemistry Techniques, Analytical, Crystallography, Dental Calculus, Dental Enamel, Dentin, Humans, Spectrophotometry, Infrared, X-Ray Diffraction
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