Cited by 136Vestibular and auditory disordersHearing, Cochlea, Tinnitus, GeneticsHearing Loss and Rehabilitation

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Role of viral infection in sudden hearing loss

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Chen, Xin, Fu, Yao-yao, Zhang, Tian-yu·2019·Journal of International Medical Research

DOI 10.1177/0300060519847860PMC PMC6683896

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Abstract

According to a recent epidemiological survey, the incidence of sudden sensorineural hearing loss (SSNHL) is increasing yearly. The cause of SSNHL is of great interest in research. To date, viral infection, vascular occlusion, abnormal cellular stress responses within the cochlea, and immune-mediated mechanisms are considered the most likely etiologies of this disease. Among these etiologies, the relationship between viral infection and sudden deafness has been unclear. In this review, we mainly discuss the viral hypothesis of SSNHL. There is little research proving or clearly indicating the pathogenesis of this disease. Further research is needed to elucidate the precise etiopathogenesis to better understand SSNHL and establish more suitable treatment to help restore hearing in affected patients.

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Тополюк, К., Дзиза, А. В., & Лупир, А. В. (2022) · ГРААЛЬ НАУКИ · doi:10.36074/grail-of-science.27.05.2022.109

Authors: Chen, X., Fu, Y.-Y., & Zhang, T.-Y.
Affiliations: Shanghai Medical College of Fudan University (CN)
ENT institute, Eye & ENT Hospital of Fudan University, Shanghai, China
ENT institute, Eye & ENT Hospital of Fudan University, Shanghai, China; Hearing Medicine Key Laboratory, National Health and Family Planning Commission, Shanghai, China
ORCID: Chen, Xin
Venue: Journal of International Medical Research
Publisher: SAGE Publications
Published: 2019-05-27
Volume: 47
Issue: 7
Pages: 2865-2872
ISSN: 0300-0605 (ISSN-L)
1473-2300
DOI: 10.1177/0300060519847860
PMC: PMC6683896
OpenAlex: W2947966724
Cited by: 136
References: 52
Citations by year: 2026: 11 · 2025: 15 · 2024: 22 · 2023: 25 · 2022: 34 · 2021: 17 · 2020: 11 · 2019: 1
FWCI: 1.64
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by-nc
creativecommons.org/licenses/by-nc/4.0/ (vor)
journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: Journal of International Medical Research (publishedVersion, cc-by-nc)
Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
PubMed Central (publishedVersion, cc-by-nc)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics: Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
Health Sciences › Health Professions › Speech and Hearing › Hearing Loss and Rehabilitation
Keywords: sudden sensorineural hearing loss, viral infection, viral hypothesis, etiopathogenesis, immune-mediated mechanisms, vascular occlusion, cellular stress response, hearing loss treatment
MeSH terms: Hearing Loss, Sudden, Humans, Prognosis, Risk Factors, Virus Diseases, Viruses

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