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Cited by 279

The DOI matches its Crossref record; 100 of the 100 references it cites were found in a registry or an index.

Clinical Staging: A Heuristic and Practical Strategy for New Research and Better Health and Social Outcomes for Psychotic and Related Mood Disorders

Open access
McGorry, Patrick D, Nelson, Barnaby, Goldstone, Sherilyn, Yung, Alison R·2010·The Canadian Journal of Psychiatry

Abstract

Most mental illnesses emerge during adolescence and early adulthood, with considerable associated distress and functional decline appearing during this critical developmental phase. Our current diagnostic system lacks therapeutic validity, particularly for the early stages of mental disorders when symptoms are still emerging and intensifying and have not yet stabilized sufficiently to fit the existing syndromal criteria. While this is, in part, due to the difficulty of distinguishing transient developmental or normative changes from the early symptoms of persistent and disabling mental illness, these factors have contributed to a growing movement for the reform of our current diagnostic system to more adequately inform the choice of therapeutic strategy, particularly in the early stages of a mental illness. The clinical staging model, which defines not only the extent of progression of a disorder at a particular point in time but also where a person lies currently along the continuum of the course of an illness, is particularly useful as it differentiates early, milder clinical phenomena from those that accompany illness progression and chronicity. This will not only enable clinicians to select treatments relevant to earlier stages of an illness, where such interventions are likely to be more effective and less harmful than treatments delivered later in the course of illness, but also allow a more efficient integration of our rapidly expanding knowledge of the biological, social, and psychological vulnerability factors involved in the development of mental illness into a useful diagnostic framework.

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Metadata

Authors
McGorry, P. D., Nelson, B., Goldstone, S., & Yung, A. R.
Venue
The Canadian Journal of Psychiatry
Published
2010-08
Volume
55
Issue
8
Pages
486-497
ISSN
  • 0706-7437 (ISSN-L)
  • 1497-0015
OpenAlex
W166433667
Cited by
279
References
100
FWCI
9.17
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Clinical Staging: A Heuristic and Practical Strategy for New Research and Better Health and Social Outcomes for Psychotic and Related Mood Disorders. https://app.cochat.ai/papers/10.1177/070674371005500803
The paper
McGorry, P. D., Nelson, B., Goldstone, S., & Yung, A. R. (2010). Clinical Staging: A Heuristic and Practical Strategy for New Research and Better Health and Social Outcomes for Psychotic and Related Mood Disorders. The Canadian Journal of Psychiatry. https://doi.org/10.1177/070674371005500803

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.