Cardiomyocyte-Specific BMAL1 Plays Critical Roles in Metabolism, Signaling, and Maintenance of Contractile Function of the Heart

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1006/abio.1987.9999 · Cited by 65,515

Real time quantitative PCR.Preprint

Heid, C., Stevens, J., Livak, K. J., & Williams, P. (1996) · Genome Research · doi:10.1101/gr.6.10.986 · Cited by 6,180

Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice

Turek, F. W., Joshu, C., Kohsaka, A., Lin, E., Ivanova, G., McDearmon, E., Laposky, A., Losee-Olson, S., Easton, A., Jensen, D. R., et al. (2005) · Science · doi:10.1126/science.1108750 · Cited by 2,485

The mammalian circadian timing system: organization and coordination of central and peripheral clocks

Dibner, C., Schibler, U., & Albrecht, U. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135821 · Cited by 2,421

A novel method for real time quantitative RT-PCR.Preprint

Gibson, U. E., Heid, C., & Williams, P. M. (1996) · Genome Research · doi:10.1101/gr.6.10.995 · Cited by 2,090

Role of the CLOCK Protein in the Mammalian Circadian Mechanism

Gekakis, N., Staknis, D., Nguyen, H. B., Davis, F. C., Wilsbacher, L. D., King, D. P., Takahashi, J. S., & Weitz, C. J. (1998) · Science · doi:10.1126/science.280.5369.1564 · Cited by 2,035

[1] Citrate synthase

Srere, P. A. (1969) · Methods in Enzymology · doi:10.1016/0076-6879(69)13005-0 · Cited by 2,005

Circadian integration of metabolism and energetics

Bass, J., & Takahashi, J. S. (2010) · Science · doi:10.1126/science.1195027 · Cited by 1,910

Mutagenesis and Mapping of a Mouse Gene, Clock , Essential for Circadian Behavior

Vitaterna, M. H., King, D. P., Chang, A.-M., Kornhauser, J. M., Lowrey, P. L., McDonald, J. D., Dove, W. F., Pinto, L. H., Turek, F. W., & Takahashi, J. S. (1994) · Science · doi:10.1126/science.8171325 · Cited by 1,632

Mop3 is an essential component of the master circadian pacemaker in mammals.

Bunger, M. K., Wilsbacher, L. D., Moran, S. M., Clendenin, C., Radcliffe, L. A., Hogenesch, J. B., Simon, M. C., Takahashi, J. S., & Bradfield, C. A. (2000) · Cell · doi:10.1016/s0092-8674(00)00205-1 · Cited by 1,621

An overview of the emerging interface between cardiac metabolism, redox biology and the circadian clock

Garcia, R. A. P., Darley-Usmar, V. M., & Young, M. E. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.02.013 · Cited by 20

Circadian Rhythm of Lipid Metabolism in Health and Disease

Zhang, Z., Xin, H., & Li, M. (2020) · Small Methods · doi:10.1002/smtd.201900601 · Cited by 21

Molecular basis of Period 1 regulation by adrenergic signaling in the heart

de Jesus, I. C. G., Araújo, F. M., Mesquita, T., Júnior, N. N. S., Silva, M. M., Morgan, H. J. N., Silva, K. S. D. C., Silva, C. L. A., Birbrair, A., Amaral, F. A., et al. (2021) · The FASEB Journal · doi:10.1096/fj.202100441r · Cited by 20

The role of the cardiomyocyte circadian clocks in ion channel regulation and cardiac electrophysiology

Schroder, E. A., Ono, M., Johnson, S. R., Rozmus, E. R., Burgess, D. E., Esser, K. A., & Delisle, B. P. (2022) · The Journal of Physiology · doi:10.1113/jp282402 · Cited by 22

Circadian Rhythms of Early Afterdepolarizations and Ventricular Arrhythmias in a Cardiomyocyte Model

Diekman, C. O., & Wei, N. (2020) · Biophysical Journal · doi:10.1016/j.bpj.2020.11.2264 · Cited by 20

Novel Roles for the Transcriptional Repressor E4BP4 in Both Cardiac Physiology and Pathophysiology

Mia, S., Sonkar, R., Williams, L. J., Latimer, M. N., Rawnsley, D. R., Rana, S., He, J., Dierickx, P., Kim, T., Xie, M., et al. (2023) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2023.03.016 · Cited by 19

Impacts of Circadian Gene Period2 Knockout on Intestinal Metabolism and Hepatic Antioxidant and Inflammation State in Mice

Zhen, Y., Xi, Z., Hu, L., Chen, Y., Ge, L., Wei, W., Loor, J. J., Yang, Q., & Wang, M. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/7896371 · Cited by 21

Metabolic and Biochemical Stressors in Diabetic Cardiomyopathy

Kain, V., & Halade, G. V. (2017) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2017.00031 · Cited by 21

Molecular link between circadian clocks and cardiac function: a network of core clock, slave clock, and effectors

Xu, W., Jain, M. K., & Zhang, L. (2020) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2020.10.006 · Cited by 18

REV-ERB is essential in cardiac fibroblasts homeostasis

Luo, X., Song, S., Qi, L., Tien, C., Li, H., Xu, W., Mathuram, T. L., Burris, T. P., Zhao, Y., Sun, Z., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.899628 · Cited by 17

Rhythm is essential: Unraveling the relation between the circadian clock and cancer

Ogunlusi, O., Ghosh, A., Sarkar, M., Carter, K., Davuluri, H., Chakraborty, M., Eckel‐Mahan, K. L., Keene, A. C., Menet, J. S., Bell‐Pedersen, D., et al. (2025) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2025.104632 · Cited by 17

Research progress on circadian clock genes in common abdominal malignant tumors (Review)

Yang, S., Ren, Q., Wen, L., Hu, J., & Wang, H. (2017) · Oncology Letters · doi:10.3892/ol.2017.6856 · Cited by 17

Circadian Rhythms in Environmental Health Sciences

Leung, J. M., & Martinez, M. E. (2020) · Current Environmental Health Reports · doi:10.1007/s40572-020-00285-2 · Cited by 20

Circadian Control of Cardiac Metabolism: Physiologic Roles and Pathologic Implications

Young, M. E. (2017) · Methodist DeBakey Cardiovascular Journal · doi:10.14797/mdcj-13-1-15 · Cited by 16

Amelioration of circadian disruption and calcium-handling protein defects by choline alleviates cardiac remodeling in abdominal aorta coarctation rats

He, X., Yang, S., Deng, J., Wu, Q., & Zang, W. (2021) · Laboratory Investigation · doi:10.1038/s41374-021-00578-6 · Cited by 16

Cardiomyocyte-specific disruption of the circadian BMAL1–REV-ERBα/β regulatory network impacts distinct miRNA species in the murine heart

Latimer, M. N., Williams, L. J., Shanmugan, G., Carpenter, B. J., Lazar, M. A., Dierickx, P., & Young, M. E. (2023) · Communications Biology · doi:10.1038/s42003-023-05537-z · Cited by 15

Circadian Governance of Cardiac Growth

Latimer, M. N., & Young, M. E. (2022) · Cells · doi:10.3390/cells11091494 · Cited by 16

Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 1: Basic and Translational Aspects

Delisle, B. P., George, A. L., Nerbonne, J. M., Bass, J. T., Ripplinger, C. M., Jain, M. K., Hermanstyne, T. O., Young, M. E., Kannankeril, P. J., Duffy, J. F., et al. (2021) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.121.010181 · Cited by 16

The Core Circadian Clock Factor, Bmal1 , Transduces Sex-specific Differences in Both Rhythmic and Nonrhythmic Gene Expression in the Mouse Heart

Zhang, X., Procopio, S. B., Ding, H., Semel, M. G., Schroder, E. A., Viggars, M. R., Seward, T. S., Du, P., Wu, K. G., Johnson, S. R., et al. (2024) · Function · doi:10.1093/function/zqae053 · Cited by 18

Augmented Cardiac Growth Hormone Signaling Contributes to Cardiomyopathy Following Genetic Disruption of the Cardiomyocyte Circadian Clock

Sonkar, R., Berry, R., Latimer, M. N., Prabhu, S. D., Young, M. E., & Frank, S. J. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.836725 · Cited by 14

Different levels of circadian (de)synchrony – where does it hurt?

Galinde, A. A., Al‐Μughales, F., Oster, H., & Heyde, I. (2022) · F1000Research · doi:10.12688/f1000research.127234.2 · Cited by 13

Diurnal expression of Dgat2 induced by time‐restricted feeding maintains cardiac health in the Drosophila model of circadian disruption

Guo, Y., Daya, F. A., Le, H. D., Panda, S., & Melkani, G. C. (2024) · Aging Cell · doi:10.1111/acel.14169 · Cited by 13

Unveiling Immune Infiltration Characterizing Genes in Hypertrophic Cardiomyopathy Through Transcriptomics and Bioinformatics

Gong, J., Shi, B., Yang, P., Khan, A., Xiong, T., & Li, Z. (2024) · Journal of Inflammation Research · doi:10.2147/jir.s454446 · Cited by 13

Diurnal, metabolic and thermogenic alterations in a murine model of accelerated aging

Allison, D. B., Ren, G., Garcia, R. A. P., Mia, S., McGinnis, G. R., Davis, J. A., Gamble, K. L., Kim, J., & Young, M. E. (2020) · Chronobiology International · doi:10.1080/07420528.2020.1796699 · Cited by 12

Aging disrupts the temporal organization of antioxidant defenses in the heart of male rats and phase shifts circadian rhythms of systolic blood pressure

Altamirano, F. G., Castro-Pascual, I. C., Ferramola, M. L., Tula, M. L., Delgado, S. M., Anzulovich, A. C., & Lacoste, M. G. (2021) · Biogerontology · doi:10.1007/s10522-021-09938-7 · Cited by 13

The Role of Circadian Clock Genes in Critical Illness: The Potential Role of Translational Clock Gene Therapies for Targeting Inflammation, Mitochondrial Function, and Muscle Mass in Intensive Care

Poole, J., & Ray, D. W. (2022) · Journal of Biological Rhythms · doi:10.1177/07487304221092727 · Cited by 13

Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids

Wintzinger, M., Panta, M., Miz, K., Prabakaran, A. D., Durumutla, H. B., Sargent, M. A., Peek, C. B., Bass, J. T., Molkentin, J. D., & Quattrocelli, M. (2022) · Molecular Metabolism · doi:10.1016/j.molmet.2022.101528 · Cited by 12

BMAL1 plays a critical role in the protection against cardiac hypertrophy through autophagy in vitro

Yu, L., Ren, L., & Dong, L. (2022) · BMC Cardiovascular Disorders · doi:10.1186/s12872-022-02822-3 · Cited by 13

β-Hydroxybutyrate dehydrogenase 1: A promising therapeutic target for diverse diseases

Ma, X., Wang, Z., Gao, H., Zhu, D., Wu, M., Zhao, L., & Xiao, W. (2025) · Biochemical Pharmacology · doi:10.1016/j.bcp.2025.117070 · Cited by 12

One Health: Circadian Medicine Benefits Both Non-human Animals and Humans Alike

Farag, H. I., Murphy, B. A., Templeman, J. R., Hanlon, C., Joshua, J., Koch, T. G., Niel, L., Shoveller, A. K. K., Bédécarrats, G. Y., Ellison, A., et al. (2024) · Journal of Biological Rhythms · doi:10.1177/07487304241228021 · Cited by 12

Circadian cardiac NAD+ metabolism, from transcriptional regulation to healthy aging

Carpenter, B. J., & Dierickx, P. (2022) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00239.2022 · Cited by 11

Voluntary Wheel Running Exercise Does Not Attenuate Circadian and Cardiac Dysfunction Caused by Conditional Deletion of Bmal1

Yusifova, M., Yusifov, A., Polson, S. M., Todd, W. D., Schmitt, E. E., & Bruns, D. R. (2023) · Journal of Biological Rhythms · doi:10.1177/07487304231152398 · Cited by 11

The vascular clock system generates the intrinsic circadian rhythm of vascular contractility

Saito, T. (2015) · Journal of Smooth Muscle Research · doi:10.1540/jsmr.51.95 · Cited by 11

Transcriptional changes during isoproterenol-induced cardiac fibrosis in mice

Nanda, D., Pant, P., Machha, P., Sowpati, D. T., & Kumarswamy, R. (2023) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2023.1263913 · Cited by 10

Identification of circadian rhythm-related gene classification patterns and immune infiltration analysis in heart failure based on machine learning

Wang, X., Rao, J., Zhang, L., Liu, X., & Zhang, Y. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e27049 · Cited by 13

Cardiovascular diseases: a therapeutic perspective around the clock

Soares, A. C., & Fonseca, D. A. (2020) · Drug Discovery Today · doi:10.1016/j.drudis.2020.04.006 · Cited by 10

Sex Inclusion in Transcriptome Studies of Daily Rhythms

Obodo, D., Outland, E. H., & Hughey, J. (2022) · Journal of Biological Rhythms · doi:10.1177/07487304221134160 · Cited by 11

Old and New Roles and Evolving Complexities of Cardiovascular Clocks.

Xu, Y., Pi, W., & Rudic, R. D. (2019) · PubMed Central · Cited by 9

New insight into methamphetamine-associated heart failure revealed by transcriptomic analyses: Circadian rhythm disorder

Zhang, C., Chen, C., Zhao, X., Lu, J., Zhang, M., Qiu, H., Yue, X., & Wang, H. (2022) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2022.116172 · Cited by 11

Identification of the potential biomarkers associated with circadian rhythms in heart failure

Sun, Q., Zhao, J., Liu, L., Wang, X., & Gu, X. (2023) · PeerJ · doi:10.7717/peerj.14734 · Cited by 8

The chronobiology of human heart failure: clinical implications and therapeutic opportunities

Gentile, F., Emdin, M., Passino, C., Montuoro, S., Tognini, P., Floras, J. S., O'Neill, J. M., & Giannoni, A. (2024) · Heart Failure Reviews · doi:10.1007/s10741-024-10447-1 · Cited by 9

Role of circadian transcription factor REV-ERB in cardiovascular diseases: a review

Wang, C., Yang, J., Yuan, J., Wang, X., Li, Q., Ren, C., Zhi, X., Lv, X., Liu, K., Zhao, X., et al. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1516279 · Cited by 12

Circadian rhythms in cardiac metabolic flexibility

Young, M. E., & Latimer, M. N. (2021) · Chronobiology International · doi:10.1080/07420528.2021.1939366 · Cited by 9

Uremia increases QRS duration afterβ-adrenergic stimulation in mice

Thomsen, M. B., Nielsen, M. S., Aarup, A., Bisgaard, L. S., & Pedersen, T. X. (2018) · Physiological Reports · doi:10.14814/phy2.13720 · Cited by 9

Time Restricted Feeding to the Light Cycle Dissociates Canonical Circadian Clocks and Physiological Rhythms in Heart Rate

Schroder, E. A., & Delisle, B. P. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.910195 · Cited by 9

Do Disruptions in the Circadian Timing System Contribute to Autonomic Dysfunction in Huntington's Disease?

Park, S., & Colwell, C. S. (2019) · PubMed Central · Cited by 9

CircadiPy: An open-source toolkit for analyzing chronobiology time series

Carvalho‐Moreira, J. P., Guarnieri, L. D. O., Passos, M. C., Emrich, F., Bargi‐Souza, P., Garcia, R. A. P., & Moraes, M. F. D. (2024) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2024.110245 · Cited by 8

Effects of time-restricted exercise on activity rhythms and exercise-induced adaptations in the heart

Dial, M. B., Malek, E. M., Neblina, G. A., Cooper, A. R., Vaslieva, N. I., Frommer, R., Girgis, M., Dawn, B., & McGinnis, G. R. (2024) · Scientific Reports · doi:10.1038/s41598-023-50113-4 · Cited by 8

Circadian control of histone turnover during cardiac development and growth

Arrieta, A., Chapski, D. J., Reese, A., Kimball, T. H., Song, K., Rosa‐Garrido, M., & Vondriska, T. M. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.107434 · Cited by 11

Daily rhythms in heartbeat rate are intrinsic to the zebrafish heart

Fong, C. K., Hearn, T. J., Webb, S., Steindal, I. A. F., Miller, A. L., & Whitmore, D. (2021) · Current Biology · doi:10.1016/j.cub.2021.01.106 · Cited by 8

Circadian Biology: The Early Bird Catches the Morning Shift

Gamble, K. L., & Young, M. E. (2015) · Current Biology · doi:10.1016/j.cub.2015.02.004 · Cited by 8

Comparisons of chromosome Y-substituted mouse strains reveal that the male-specific chromosome modulates the effects of androgens on cardiac functions

Praktiknjo, S. D., Picard, S., & Deschepper, C. F. (2016) · Biology of Sex Differences · doi:10.1186/s13293-016-0116-4 · Cited by 8

Circadian Deregulation as Possible New Player in Pollution-Induced Tissue Damage

Benedusi, M., Frigato, E., Bertolucci, C., & Valacchi, G. (2021) · Atmosphere · doi:10.3390/atmos12010116 · Cited by 8

Epigenetic Mechanisms in the Transcriptional Regulation of Circadian Rhythm in Mammals

Mao, W., Ge, X., Chen, Q., & Li, J. (2025) · Biology · doi:10.3390/biology14010042 · Cited by 9

BMAL1 in Ischemic Heart Disease: A Narrative Review from Molecular Clock to Myocardial Pathology

Yang, J., Zhao, J., Chen, Z., Duan, L., Yang, H. Y., & Cai, D. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26104626 · Cited by 7

Role of circadian rhythms in heart failure: insights from myocardial energy metabolism

Wang, P., Yu, B., Liu, L., Zhang, C., & Ai, S. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06828-1 · Cited by 7

Cardiac circadian rhythms in time and space: The future is in 4D

Chirico, N., Laake, L. W. V., Sluijter, J. P. G., van Mil, A., & Dierickx, P. (2020) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2020.11.006 · Cited by 8

Circadian determinants of heart rhythm and arrhythmias

Boyett, M. R., Li, P., Xiang, Y., Zhang, H., Kim, J. K., & D’Souza, A. (2025) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2025.08.012 · Cited by 8

Circadian Biology in Obstructive Sleep Apnea-Associated Cardiovascular Disease

Gaspar, L. S., Pyakurel, S., Xu, N., D’Souza, S. P., & Koritala, B. S. C. (2025) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2025.03.008 · Cited by 5

Time-restricted feeding mediated synchronization of circadian rhythms to sustain cardiovascular health

Melkani, G. C. (2025) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2025.07.007 · Cited by 7

Association of total sleep duration variability with risk of new stroke in the middle-aged and elderly Chinese population

Ma, J., Ma, N., Zhang, L., Xu, L., Liu, X., & Meng, G. (2024) · BMC Neurology · doi:10.1186/s12883-024-03727-8 · Cited by 6

Rest-activity rhythms and cardiovascular events in cardiovascular–kidney–metabolic syndrome: evidence from two nationwide cohorts

Weng, B., Chen, H., Chen, H., Wang, N., Feng, H., Yang, K., & Tan, X. (2026) · American Journal of Preventive Cardiology · doi:10.1016/j.ajpc.2026.101414 · Cited by 5

Timed use of digoxin prevents heart ischemia–reperfusion injury through a REV-ERBα–UPS signaling pathway

Vinod, M., Berthier, A., Maréchal, X., Gheeraert, C., Boutry, R., Delhaye, S., Annicotte, J., Duez, H., Hovasse, A., Cianférani, S., et al. (2022) · Nature Cardiovascular Research · doi:10.1038/s44161-022-00148-z · Cited by 5

Deficiency of circadian gene cryptochromes in bone marrow‐derived cells protects against atherosclerosis in LDLR −/− mice

Lin, Y., Tsai, M., Hsieh, C., Wen, M., & Wang, C. (2021) · The FASEB Journal · doi:10.1096/fj.202001818rrr · Cited by 5

A brief history of circadian time in the heart

Young, M. E., Khanna, V., Metcalfe, M., Rameshkumar, N., Harington, S., Li, L. H., Doost, J. S., Taegtmeyer, H., & Martino, T. A. (2025) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2025.08.005 · Cited by 5

Circadian biology of cardiac aging

Bettadapura, S. S., Todd, W. D., McGinnis, G. R., & Bruns, D. R. (2025) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2024.12.001 · Cited by 4

Circadian genes and circulatory system

Atkov, O. Y., & Gorokhova, S. G. (2019) · Russian Cardiology Bulletin · doi:10.17116/cardiobulletin20191402136 · Cited by 4

The association of polymorphisms in related circadian rhythm genes and clopidogrel resistance susceptibility

Su, J., Yu, Q., Yang, J., Zheng, N., Zhong, J., Ji, L., Li, J., & Chen, X. (2021) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.13622 · Cited by 4

Disease Implications of the Circadian Clocks and Microbiota Interface

Tran, L. B., Forsyth, C. B., Bishehsari, F., Voigt, R. M., Keshavarzian, A., & Swanson, G. R. (2021) · Springer eBooks · doi:10.1007/978-3-030-72158-9_17 · Cited by 4

Longitudinal association between accelerometer-derived rest–activity rhythm and atherosclerotic cardiovascular disease

Huang, L., Li, Y., Xu, X., Chen, W., Zhang, Z., Sun, L., & Gao, X. (2024) · Sleep Medicine · doi:10.1016/j.sleep.2024.06.004 · Cited by 3

Healthy sleep patterns and risk of incident cardiovascular disease, liver-related events, and all-cause mortality among individuals with metabolic dysfunction--associated steatotic liver disease: A large prospective cohort study

Wang, S., Liao, Y., Deng, Y., Yu, C., Chen, X., Liu, X., Yang, Q., Chen, X., Chen, X., & Xue, H. (2025) · Sleep Health · doi:10.1016/j.sleh.2025.07.007 · Cited by 3

Circadian transcriptional repressors REV-ERBα/β and E4BP4 regulate cardiac function

Wang, Y. H., & Dierickx, P. (2025) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2025.09.001 · Cited by 3

Role of circadian rhythms in metabolic syndrome

Bhatnagar, A., Puppala, A., Rankawat, S., Ray, S., & Ray, S. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-85732-1.00006-2 · Cited by 3

Research Progress of BMAL1 in Heart Failure

Chen, F., Yang, H., Fu, X., Liu, Z. Y., Chen, Y., Xu, T., Chen, Z., Luo, X., Wang, C., & Guo, Y. (2025) · Journal of the American Heart Association · doi:10.1161/jaha.125.043244 · Cited by 2

Cardiac Lipid Metabolism: Cells, Metabolites, and Rhythms

Goldberg, I. J., Young, M. E., Schulze, P. C., & Drosatos, K. (2026) · Circulation Research · doi:10.1161/circresaha.126.327471 · Cited by 3

The role of circadian rhythms and the “cellular clock” in age-associated diseases

Панченко, А. В., Александровна, Г. Е., & Anisimov, V. N. (2017) · Advances in Gerontology · doi:10.1134/s2079057017010131 · Cited by 2

Characteristics of Sleep in Critically Ill Patients: Part II: Circadian Rhythm Disruption

Mélone, M.-A., & Gehlbach, B. K. (2022) · Springer eBooks · doi:10.1007/978-3-031-06447-0_2 · Cited by 2

Bromide impairs the circadian clock and glycolytic homeostasis via disruption of autophagy in rat H9C2 cardiomyocytes

Jiang, Y., Gu, Y., Xu, H., Tian, X., Zhang, X., Xu, X., Yan, W., & Zhang, X. (2020) · BMC Molecular and Cell Biology · doi:10.1186/s12860-020-00289-8 · Cited by 2

Circadian-Regulated Cardiac Metabolism Involves Transcription Factor E4BP4

Rabinovich-Nikitin, I., & Kirshenbaum, L. A. (2023) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2023.06.011 · Cited by 2

Cardiac Timeless Trans-Organically Regulated by miR-276 in Adipose Tissue Modulates Cardiac Function

Tang, C., Li, Q., Wang, X., Yu, Z., Ping, X., Qin, Y., Liu, Y., & Zheng, L. (2023) · Function · doi:10.1093/function/zqad064 · Cited by 2

Severe attenuation of circadian clock output in the heart following sustained augmentation of cardiomyocyte protein O-GlcNAcylation

Shanmugam, G., Chang, S. F., Collins, H. E., Ha, C., Kane, M. S., Potter, L., Xie, L., Zou, L., Zhang, J., Chatham, J. C., et al. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1601407 · Cited by 1

Twenty‐Four Hour Rhythms in Cardiovascular Physiology

Thomsen, M. B. (2025) · Acta Physiologica · doi:10.1111/apha.70116 · Cited by 1

Timing matters: circadian rhythm disruption in alcohol-associated peripheral organ pathophysiology

Bailey, S. M. (2026) · Function · doi:10.1152/function.099.2025 · Cited by 3

Circadian System and Aging in Rodent Models

Панченко, А. В., Александровна, Г. Е., & Anisimov, V. N. (2017) · Healthy ageing and longevity · doi:10.1007/978-3-319-64543-8_5 · Cited by 1

Sodium–hydrogen exchange inhibition attenuates glycoside-induced hypertrophy in rat ventricular myocytes

(2018) · Cardiovascular Research · doi:10.1093/cvr/cvx238 · Cited by 1

The Circadian–Hypoxia Link

Oyama, Y., Walker, L. A., & Eckle, T. D. L. G. (2024) · Royal Society of Chemistry eBooks · doi:10.1039/bk9781839167553-00136 · Cited by 1

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