Young, Martin E.

Reduced Mitochondrial Oxidative Capacity and Increased Mitochondrial Uncoupling Impair Myocardial Energetics in Obesity

Boudina, S., Sena, S., O’Neill, B. T., Tathireddy, P., Young, M. E., & Abel, E. D. (2005) · Circulation

Mitochondrial Function and PathologyCardiovascular Function and Risk Factors

Cited by 502

Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression

Bray, M. S., Shaw, C. A., Moore, M. W. S., Garcia, R. A. P., Zanquetta, M. M., Durgan, D. J., Jeong, W. J., Tsai, J.-Y., Bugger, H., Zhang, D., et al. (2008) · American Journal of Physiology-Heart and Circulatory Physiology

Circadian rhythm and melatoninCardiac electrophysiology and arrhythmias

Cited by 384

Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte

Chan, A. Y. M., Soltys, C.-L. M., Young, M. E., Proud, C. G., & Dyck, J. R. B. (2004) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 331

Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression

Belke, D. D., Betuing, S., Tuttle, M. J., Graveleau, C., Young, M. E., Pham, M., Zhang, D., Cooksey, R. C., McClain, D. A., Litwin, S. E., et al. (2002) · Journal of Clinical Investigation

Congenital heart defects researchCardiovascular Function and Risk Factors

Cited by 330

The Cardiomyocyte Circadian Clock: Emerging Roles in Health and Disease

Durgan, D. J., & Young, M. E. (2010) · Circulation Research

Circadian rhythm and melatoninCardiac electrophysiology and arrhythmias

Cited by 277

Effects of glucocorticoid excess on the sensitivity of glucose transport and metabolism to insulin in rat skeletal muscle

DIMITRIADIS, G., LEIGHTON, B., PARRY-BILLINGS, M., SASSON, S., YOUNG, M., KRAUSE, U., BEVAN, S., PIVA, T., WEGENER, G., & NEWSHOLME, E. A. (1997) · Biochemical Journal

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 266

Short Communication: Ischemia/Reperfusion Tolerance Is Time-of-Day–Dependent: Mediation by the Cardiomyocyte Circadian Clock

Durgan, D. J., Pulinilkunnil, T., Villegas-Montoya, C., Garvey, M. E., Frangogiannis, N. G., Michael, L. H., Chow, C.-W., Dyck, J. R. B., & Young, M. E. (2010) · Circulation Research

Cardiac Ischemia and ReperfusionCircadian rhythm and melatonin

Cited by 254

Cardiomyocyte-Specific BMAL1 Plays Critical Roles in Metabolism, Signaling, and Maintenance of Contractile Function of the Heart

Young, M. E., Brewer, R. A., Peliciari-Garcia, R. A., Collins, H. E., He, L., Birky, T. L., Peden, B. W., Thompson, E. G., Ammons, B.-J., Bray, M. S., et al. (2014) · Journal of Biological Rhythms

Circadian rhythm and melatoninCardiac electrophysiology and arrhythmias

Cited by 220

Circadian rhythms in the development of obesity: potential role for the circadian clock within the adipocyte

Bray, M. S., & Young, M. E. (2007) · Obesity Reviews

Circadian rhythm and melatoninAdipokines, Inflammation, and Metabolic Diseases

Cited by 213

Differential effects of saturated and unsaturated fatty acid diets on cardiomyocyte apoptosis, adipose distribution, and serum leptin

Okere, I. C., Chandler, M. P., McElfresh, T. A., Rennison, J. H., Sharov, V., Sabbah, H. N., Tserng, K.-Y., Hoit, B. D., Ernsberger, P., Young, M. E., et al. (2006) · American Journal of Physiology-Heart and Circulatory Physiology

Fatty Acid Research and HealthPeroxisome Proliferator-Activated Receptors

Cited by 147

Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice

Dolinsky, V. W., Rogan, K. J., Sung, M. M., Zordoky, B. N., Haykowsky, M. J., Young, M. E., Jones, L. W., & Dyck, J. R. B. (2013) · American Journal of Physiology-Endocrinology and Metabolism

Chemotherapy-induced cardiotoxicity and mitigationCardiovascular Effects of Exercise

Cited by 133

Potential role for peripheral circadian clock dyssynchrony in the pathogenesis of cardiovascular dysfunction

Young, M. E., & Bray, M. S. (2007) · Sleep Medicine

Circadian rhythm and melatoninSleep and Work-Related Fatigue

Cited by 129

Low Carbohydrate/High-Fat Diet Attenuates Cardiac Hypertrophy, Remodeling, and Altered Gene Expression in Hypertension

Okere, I. C., Young, M. E., McElfresh, T. A., Chess, D. J., Sharov, V. G., Sabbah, H. N., Hoit, B. D., Ernsberger, P., Chandler, M. P., & Stanley, W. C. (2006) · Hypertension

Cardiac Fibrosis and RemodelingCardiovascular Function and Risk Factors

Cited by 104

Activation of PPARγ enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats

Golfman, L. S., Wilson, C. R., Sharma, S., Burgmaier, M., Young, M. E., Guthrie, P. H., Van Arsdall, M., Adrogue, J. V., Brown, K. K., & Taegtmeyer, H. (2005) · American Journal of Physiology-Endocrinology and Metabolism

Peroxisome Proliferator-Activated ReceptorsCardiovascular Function and Risk Factors

Cited by 99

Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21

Kim, T., Nason, S., Holleman, C., Pepin, M., Wilson, L., Berryhill, T. F., Wende, A. R., Steele, C., Young, M. E., Barnes, S., et al. (2018) · Diabetes

Fibroblast Growth Factor ResearchDrug Transport and Resistance Mechanisms

Cited by 97

Effects of chronic activation of peroxisome proliferator-activated receptor-α or high-fat feeding in a rat infarct model of heart failure

Morgan, E. E., Rennison, J. H., Young, M. E., McElfresh, T. A., Kung, T. A., Tserng, K.-Y., Hoit, B. D., Stanley, W. C., & Chandler, M. P. (2006) · American Journal of Physiology-Heart and Circulatory Physiology

Peroxisome Proliferator-Activated ReceptorsCardiovascular Function and Risk Factors

Cited by 86

The circadian clock in cardiovascular regulation and disease: Lessons from the Nobel Prize in Physiology or Medicine 2017

Van Laake, L. W., Lüscher, T. F., & Young, M. E. (2018) · European Heart Journal

Circadian rhythm and melatoninHeart Rate Variability and Autonomic Control

Cited by 74

Glucagon receptor signaling regulates weight loss via central KLB receptor complexes

Nason, S. R., Antipenko, J., Presedo, N., Cunningham, S. E., Pierre, T. H., Kim, T., Paul, J. R., Holleman, C., Young, M. E., Gamble, K. L., et al. (2021) · JCI Insight

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 34

Metabolism as an integral cog in the mammalian circadian clockwork

Gamble, K. L., & Young, M. E. (2013) · Critical Reviews in Biochemistry and Molecular Biology

Circadian rhythm and melatoninDietary Effects on Health

Cited by 18