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Lymphocytic Hypophysitis in Children: A Novel Presentation and Literature Review
Abstract
Lymphocytic hypophysitis, an autoimmune mediated chronic inflammation of the pituitary gland, is uncommon in children. 1 The usual presentation is with symptoms secondary to pressure from the enlargement of the gland itself and or impairment of pituitary hormones of varying degrees, in conjunction with a sellar mass. 2,3 In 80% of cases, partial or panhypopituitarism is present with approximately 75% of cases having multiple hormonal deficiencies. 2 We report the case of a prepubertal female who presented with cyclical vomiting, as her initial symptom of lymphocytic hypophysitis which resolved promptly after pituitary biopsy. This case suggests that cyclical vomiting can be a symptom associated with lymphocytic hypophysitis. Therefore, it should be considered in the differential diagnosis of any child presenting with cyclical vomiting.
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“Clinical findings include headaches and pituitary hormonal dysfunction, with deficiency of ACTH in adults and growth hormone in children [71].”
From Magnetic resonance imaging of sellar and juxtasellar abnormalities in the paediatric population: an imaging review (2015) · cites this paper as [71]
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Cited by
Shields, R., Mangla, R., Almast, J., & Meyers, S. (2015) · Insights into Imaging · doi:10.1007/s13244-015-0401-5 · Cited by 18
Metadata
- Authors
- Kalra, A. A., Riel-Romero, R. M. S., & Gonzalez-Toledo, E.
- Venue
- Journal of Child Neurology
- Publisher
- SAGE Publications
- Published
- 2011-01
- Volume
- 26
- Issue
- 1
- Pages
- 87-94
- ISSN
- 0883-0738
- 1708-8283
- Cited by
- 37
- References
- 0
- Language
- en
- Licence
- journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
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- Kalra, A. A., Riel-Romero, R. M. S., & Gonzalez-Toledo, E. (2011). Lymphocytic Hypophysitis in Children: A Novel Presentation and Literature Review. Journal of Child Neurology. https://doi.org/10.1177/0883073810373278
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