Clear Liquid Diet vs Soft Diet as the Initial Meal in Patients With Mild Acute Pancreatitis: A Randomized Interventional Trial
Abstract
Background Patients recovering from mild acute pancreatitis are usually started on a liquid diet and advanced to a solid diet. Evidence suggests a soft diet as the initial meal is tolerated well by such patients. However, the results are controversial. Objectives To assess the safety of starting an early soft diet compared with a liquid diet in patients with mild acute pancreatitis as the initial meal. Methods We randomized 60 patients with mild acute pancreatitis into 2 groups to receive either a clear liquid diet (CLD) or a soft diet (SD) as the initial meal, and parameters such as tolerance to diet, recurrence of pain, length of hospitalization (LOH), need to stop feeding, post-refeeding length of hospitalization (PRLOH), and postdischarge readmission rate within 30 days were analyzed. Results The demographic and baseline parameters (amylase, total leucocyte count, Balthazar score) in the 2 groups were comparable. Patients in both groups tolerated the diet well except 1 patient in the SD group, who developed vomiting and diarrhea, not severe enough to stop feeding. LOH and PRLOH were significantly lower in the SD group (4.23 ± 2.08 and 1.96 ± 1.63 days, P Conclusion In patients with mild acute pancreatitis, a soft diet as the initial meal is well tolerated and leads to a shorter total length of hospitalization.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Early oral diet causes no harm to patients with mild acute pancreatitis.
“The early oral diet causes no harm to”
From ESPEN guideline on hospital nutrition (2021) · cites this paper as [194]
That meta-analysis showed early oral feeding decreases hospital length of stay.
“but decreases hospital length of stay [194].”
From ESPEN guideline on hospital nutrition (2021) · cites this paper as [194]
A recent meta-analysis of five trials involving 313 patients showed that early oral feeding within 24 hours does not result in a significantly higher risk of rebleeding and mortality compared with delayed oral feeding.
“A recent meta-analysis of five trials involving 313 patients showed that early oral feeding within 1650 24 hours does not result in a significantly higher risk of rebleeding and mortality compared 1651 with delayed oral feeding”
From ESPEN guideline on hospital nutrition (2021) · cites this paper as [194]
Usually, a liquid diet is initiated immediately, and subsequently, a soft diet is given.
“Usually, a liquid diet is 1652 initiated immediately, and subsequently, a soft diet is given [194].”
From ESPEN guideline on hospital nutrition (2021) · cites this paper as [194]
Cites
Eckerwall, G. E., Tingstedt, B. B. Å., Bergenzaun, P. E., & Andersson, R. G. (2007) · Clinical Nutrition · doi:10.1016/j.clnu.2007.04.007 · Cited by 227 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
McClave, S. A., Taylor, B. E., Martindale, R. G., Warren, M. M., Johnson, D. R., Braunschweig, C., McCarthy, M. S., Davanos, E., Rice, T. W., Cresci, G. A., et al. (2016) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607115621863 · Cited by 3,982 · see citing works
Taylor, B. E., McClave, S. A., Martindale, R. G., Warren, M. M., Johnson, D. R., Braunschweig, C., McCarthy, M. S., Davanos, E., Rice, T. W., Cresci, G. A., et al. (2016) · Critical Care Medicine · doi:10.1097/ccm.0000000000001525 · Cited by 1,476 · see citing works
ESPEN guideline on hospital nutrition
Thibault, R., Abbasoglu, O., Ioannou, E., Meija, L., Ottens-Oussoren, K., Pichard, C., Rothenberg, E., Rubin, D., Siljamäki-Ojansuu, U., Vaillant, M.-F., et al. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.09.039 · Cited by 259 · see citing works
- Authors
- Rajkumar, N., Karthikeyan, V. S., Ali, S. M., Sistla, S. C., & Kate, V.
- Affiliations
- Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
- Corresponding author
- Kate, Vikram
- Venue
- Nutrition in Clinical Practice
- Publisher
- Wiley
- Published
- 2012-12-13
- Volume
- 28
- Issue
- 3
- Pages
- 365-370
- ISSN
- 0884-5336 (ISSN-L)
- 1941-2452
- OpenAlex
- W2163807272
- Cited by
- 40
- References
- 1
- Citations by year
- 2025: 5 · 2024: 2 · 2023: 1 · 2022: 4 · 2021: 4 · 2020: 2 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 5 · 2015: 6 · 2014: 2 · 2013: 1
- FWCI
- 2.93
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Nutrition in Clinical Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Pancreatitis Pathology and Treatment
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
- Keywords
- mild acute pancreatitis, clear liquid diet, soft diet, enteral nutrition, length of hospital stay, post-discharge readmission, pain recurrence
- MeSH terms
- Acute Disease, Adult, Amylases, Diet, Female, Hospitalization, Humans, Length of Stay, Male, Pancreatitis, Recurrence, Treatment Outcome, Young Adult, Meals
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
