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Progress in Clinical Neurosciences: Sepsis-Associated Encephalopathy: Evolving Concepts

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Sepsis induces brain mitochondrial dysfunction.

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Transcranial Doppler to assess sepsis-associated encephalopathy in critically ill patients

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Sepsis induces apoptotic cell death in different regions of the brain in a rat model of sepsis

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Glycemic Control and Excess Mortality in Type 1 Diabetes

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The dynamic change of serum S100B levels from day 1 to day 3 is more associated with sepsis-associated encephalopathy

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Alterations in the brain electrical activity in a rat model of sepsis-associated encephalopathy

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Risk factors and outcomes of urosepsis in patients with calculous pyonephrosis receiving surgical intervention: a single-center retrospective study

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Association between Elevated Serum Tau Protein Level and Sepsis-Associated Encephalopathy in Patients with Severe Sepsis

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Short-Term Effects of Sepsis and the Impact of Aging on the Transcriptional Profile of Different Brain Regions

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Somatosensory evoked potentials as predictor of systemic inflammatory response syndrome in pigs?

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Ist die F-Wellen-Entstehung abhängig von der Größe der motorischen Einheiten?

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Sepsis-associated encephalopathy: A vicious cycle of immunosuppression

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A retrospective study of sepsis-associated encephalopathy: epidemiology, clinical features and adverse outcomes

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Sepsis-Associated Brain Dysfunction: A Review of Current Literature

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The prognostic value of neurofilament levels in patients with sepsis-associated encephalopathy – A prospective, pilot observational study

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Gut Microbiota Mediates the Susceptibility of Mice to Sepsis-Associated Encephalopathy by Butyric Acid

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Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice

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Emodin Promotes Autophagy and Prevents Apoptosis in Sepsis-Associated Encephalopathy through Activating BDNF/TrkB Signaling

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The dynamic change of serum S100B levels from day 1 to day 3 is more associated with sepsis-associated encephalopathy

Wu, L., Feng, Q., Ai, M., Deng, S., Liu, Z., Huang, L., Ai, Y., & Zhang, L. (2020) · Scientific Reports · doi:10.1038/s41598-020-64200-3 · Cited by 55 · see citing works

Blocking HMGB1/RAGE Signaling by Berberine Alleviates A1 Astrocyte and Attenuates Sepsis-Associated Encephalopathy

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Rutaecarpine ameliorated sepsis-induced peritoneal resident macrophages apoptosis and inflammation responses

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Omi/HtrA2 Regulates a Mitochondria-Dependent Apoptotic Pathway in a Murine Model of Septic Encephalopathy

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Mitochondrial dynamics and protective effects of a mitochondrial division inhibitor, Mdivi-1, in lipopolysaccharide-induced brain damage

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High Mobility Group Box 1 (HMGB1): Potential Target in Sepsis-Associated Encephalopathy

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Review of the Predictive Value of Biomarkers in Sepsis Mortality

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Extracellular vesicles in sepsis plasma mediate neuronal inflammation in the brain through miRNAs and innate immune signaling

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Risk factors and outcomes of urosepsis in patients with calculous pyonephrosis receiving surgical intervention: a single-center retrospective study

Liang, X., Huang, J., Xing, M., He, L., Zhu, X., Weng, Y., Guo, Q., & Zou, W. (2019) · BMC Anesthesiology · doi:10.1186/s12871-019-0729-3 · Cited by 29 · see citing works

Inhibition of visfatin alleviates sepsis-induced intestinal damage by inhibiting Hippo signaling pathway

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SS-31 Improves Cognitive Function in Sepsis-Associated Encephalopathy by Inhibiting the Drp1-NLRP3 Inflammasome Activation

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Subcutaneous administration of β-hydroxybutyrate improves learning and memory of sepsis surviving mice

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Association between Elevated Serum Tau Protein Level and Sepsis-Associated Encephalopathy in Patients with Severe Sepsis

Zhao, T., Xia, Y., Wang, D., & Pang, L. (2019) · Canadian Journal of Infectious Diseases and Medical Microbiology · doi:10.1155/2019/1876174 · Cited by 25 · see citing works

Emerging Trends and Hot Spots in Sepsis-Associated Encephalopathy Research From 2001 to 2021: A Bibliometric Analysis

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Acetaminophen alleviates ferroptosis in mice with sepsis-associated encephalopathy via the GPX4 pathway

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Machine learning for early prediction of sepsis-associated acute brain injury

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Identification of sepsis-associated encephalopathy risk factors in elderly patients: a retrospective observational cohort study

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TIPE2 ameliorates neuroinflammation and cognitive impairment in sepsis-associated encephalopathy through regulating RhoA/ROCK2–NF-κB signaling pathway

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Application background and mechanism of short-chain fatty acids in sepsis-associated encephalopathy

Zhang, Q., Lu, C., Fan, W., Zhang, J., & Yin, Y. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1137161 · Cited by 23 · see citing works

Short-Term Effects of Sepsis and the Impact of Aging on the Transcriptional Profile of Different Brain Regions

Hamasaki, M. Y., Severino, P., Puga, R., Koike, M. K., Hernandes, C., Barbeiro, H. V., Barbeiro, D. F., Machado, M. C. C., Reis, E. M. R., & da Silva, F. P. (2019) · Inflammation · doi:10.1007/s10753-019-00964-9 · Cited by 23 · see citing works

Mechanical Learning for Prediction of Sepsis-Associated Encephalopathy

Zhao, L., Wang, Y., Ge, Z., Zhu, H., & Li, Y. W. (2021) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2021.739265 · Cited by 23 · see citing works

Potential Neuroprotective Role of Melatonin in Sepsis-Associated Encephalopathy Due to Its Scavenging and Anti-Oxidative Properties

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The nomogram to predict the occurrence of sepsis-associated encephalopathy in elderly patients in the intensive care units: A retrospective cohort study

Zhao, Q., Xiao, J., Liu, X., & Liu, H. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1084868 · Cited by 21 · see citing works

Factors contributing to sepsis-associated encephalopathy: a comprehensive systematic review and meta-analysis

Zhang, Z., Guo, L., Jia, L., Duo, H., Shen, L., & Zhao, H. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1379019 · Cited by 20 · see citing works

Clinical features, electroencephalogram, and biomarkers in pediatric sepsis-associated encephalopathy

de Araújo, B. E. S., Fontana, R. D. S., de Magalhães‐Barbosa, M. C., Lima‐Setta, F., Paravidino, V. B., Riveiro, P. M., Pulcheri, L., Salú, M. D. S., de Oliveira, M. B. G., Robaina, J. R., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-14853-z · Cited by 19 · see citing works

Identification of IL-8 in CSF as a potential biomarker in sepsis-associated encephalopathy

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Pentamidine protects mice from cecal ligation and puncture-induced brain damage via inhibiting S100B/RAGE/NF-κB

Huang, L., Zhang, L., Liu, Z., Zhao, S., Xu, D., Li, L., Peng, Q., & Ai, Y. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.07.045 · Cited by 18 · see citing works

Posterior Reversible Encephalopathy in Sepsis-Associated Encephalopathy: Experience from a Single Center

Orhun, G., Sencer, S., Tüzün, E., Bebek, N., Özcan, P. E., Barbüroğlu, M., Günver, M. G., & Esen, F. (2022) · Neurocritical Care · doi:10.1007/s12028-021-01433-8 · Cited by 18 · see citing works

Endothelial glycocalyx-associated molecules as potential serological markers for sepsis-associated encephalopathy: A systematic review and meta-analysis

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Polydatin Improves Sepsis-Associated Encephalopathy by Activating Sirt1 and Reducing p38 Phosphorylation

Huang, L., Chen, J., Li, X., Mingxin, H., Liu, J., Qin, N., Zeng, Z., Wang, X., Li, F., & Yang, H. S. (2022) · Journal of Surgical Research · doi:10.1016/j.jss.2022.03.008 · Cited by 17 · see citing works

Electroacupuncture prevents LPS- induced neuroinflammation via upregulation of PICK-TLR4 complexes in the microglia of hippocampus

Mo, Y., Wang, L., Ren, M., Xie, W., Ye, X., Zhou, B., Zhang, A., Dai, Q., & Wang, J. (2021) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2021.10.010 · Cited by 17 · see citing works

Amitriptyline Reduces Sepsis-Induced Brain Damage Through TrkA Signaling Pathway

Zhang, L., Peng, X., Ai, Y., Li, L., Zhao, S., Liu, Z., Peng, Q., Deng, S., Huang, Y., Mo, Y., et al. (2020) · Journal of Molecular Neuroscience · doi:10.1007/s12031-020-01611-x · Cited by 16 · see citing works

Effects of MFHAS1 on cognitive impairment and dendritic pathology in the hippocampus of septic rats

Zhong, J., Guo, C., Hou, W., Shen, N., & Miao, C. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.116822 · Cited by 15 · see citing works

ROLE OF MICROGLIA IN SEPSIS-ASSOCIATED ENCEPHALOPATHY PATHOGENESIS: AN UPDATE

Yu, Z., Shi, H., Zhang, J., Ma, C., He, C., Yang, F., & Zhao, L. (2023) · Shock · doi:10.1097/shk.0000000000002296 · Cited by 15 · see citing works

Improved prediction of sepsis-associated encephalopathy in intensive care unit sepsis patients with an innovative nomogram tool

Jin, J. J., Yu, L., Zhou, Q., & Zeng, M. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1344004 · Cited by 15 · see citing works

Non-hepatic Hyperammonemia: A Potential Therapeutic Target for Sepsis-associated Encephalopathy

Zhao, L., Li, Y., Wang, Y., Ge, Z., Zhu, H., Zhou, X., & Li, Y. W. (2021) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527321666211221161534 · Cited by 15 · see citing works

Spectroscopy detects skeletal muscle microvascular dysfunction during onset of sepsis in a rat fecal peritonitis model

Kowalewska, P. M., Kowalewski, J. E., Milkovich, S., Sové, R. J., Wang, L., Whitehead, S. N., & Ellis, C. G. (2022) · Scientific Reports · doi:10.1038/s41598-022-10208-w · Cited by 15 · see citing works

Review on the Role of Mitochondrial Dysfunction in Septic Encephalopathy

Fu, C., Weng, S., Liu, D., Guo, R., Chen, M., Shi, B., & Weng, J. (2024) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-024-01493-5 · Cited by 14 · see citing works

Sex, sepsis and the brain: defining the role of sexual dimorphism on neurocognitive outcomes after infection

Polcz, V. E., Barrios, E. L., Chapin, B. A., Price, C. C., Nagpal, R., Chakrabarty, P., Casadesús, G., Foster, T. C., Moldawer, L. L., & Efron, P. A. (2023) · Clinical Science · doi:10.1042/cs20220555 · Cited by 14 · see citing works

Disrupted metabolic and spontaneous neuronal activity of hippocampus in sepsis associated encephalopathy rats: A study combining magnetic resonance spectroscopy and resting-state functional magnetic resonance imaging

Li, H., Liao, H., Zhang, C., Xu, Y., Xu, X., Chen, Y., Song, S., Li, Q., Si, Y., & Bao, H. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1032098 · Cited by 13 · see citing works

Endoplasmic reticulum stress regulates cell injury in lipopolysaccharide-induced nerve cells

Li, M., Zhang, Y., & Wang, J. (2020) · Journal of International Medical Research · doi:10.1177/0300060520949762 · Cited by 13 · see citing works

The molecular basis of brain injury in preterm infants with sepsis - associated encephalopathy

Gong, X., Weng, B., Zhang, X., Yan, C., & Cai, C. (2022) · BMC Pediatrics · doi:10.1186/s12887-022-03372-5 · Cited by 12 · see citing works

A summary of the current diagnostic methods for, and exploration of the value of microRNAs as biomarkers in, sepsis-associated encephalopathy

Yuechen, Z., Xi, S., Zhouxing, Z., Gu, F., & Hu, W. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1125888 · Cited by 12 · see citing works

Insight Into Regulatory T Cells in Sepsis-Associated Encephalopathy

Gao, Y.-L., Liu, Y.-C., Zhang, X., Shou, S.-T., & Chai, Y.-F. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.830784 · Cited by 11 · see citing works

Relationship between Nonhepatic Serum Ammonia Levels and Sepsis-Associated Encephalopathy: A Retrospective Cohort Study

Wang, P., Yan, J., Shi, Q., Yang, F., Li, X., Shen, Y., Liu, H., Xie, K., & Zhao, L. (2023) · Emergency Medicine International · doi:10.1155/2023/6676033 · Cited by 11 · see citing works

Clinical Features and Factors Associated With Sepsis-Associated Encephalopathy in Children: Retrospective Single-Center Clinical Study

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