The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
A review of the toxic effects and mechanisms of action of fumonisin B1
Abstract
Fumonisin B 1(FB 1) is a mycotoxin produced by the fungus Fusarium verticillioides, which commonly infects corn and other agricultural products. Fusarium species can also be found in moisture-damaged buildings, and, therefore, exposure of humans to Fusarium mycotoxins including FB 1 may take place. FB 1 bears a clear structural similarity to the cellular sphingolipids, and this similarity has been shown to disturb the metabolism of sphingolipids by inhibiting the enzyme ceramide synthase leading to accumulation of sphinganine in cells and tissues. FB 1 is neurotoxic, hepatotoxic, and nephrotoxic in animals, and it has been classified as a possible carcinogen to humans. The cellular mechanisms behind FB 1-induced toxicity include the induction of oxidative stress, apoptosis, and cytotoxicity, as well as alterations in cytokine expression. The effects of FB 1 on different parameters vary markedly depending on what types of cells are studied or what species they originate from. These aspects are important to consider when evaluating the toxic potential of FB 1.
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Some traditional herbal medicines, some mycotoxins, naphthalene and styrene.
Anttila, A., Bhat, R. V., Bond, J. A., Borghoff, S. J., Bosch, F. X., Carlson, G. P., Castegnaro, M., Cruzan, G., Gelderblom, W. C. A., Hass, U., et al. (2002) · PubMed · Cited by 1,674
Fumonisins--novel mycotoxins with cancer-promoting activity produced by Fusarium moniliforme
Gelderblom, W. C., Jaskiewicz, K., Marasas, W. F., Thiel, P. G., Horak, R. M., Vleggaar, R., & Kriek, N. P. (1988) · Applied and Environmental Microbiology · doi:10.1128/aem.54.7.1806-1811.1988 · Cited by 1,263
Wang, E., Norred, W. P., Bacon, C. W., Riley, R. T., & Merrill, A. H. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)98712-0 · Cited by 1,113
Bose, R., Verheij, M., Haimovitz-Friedman, A., Scotto, K., Fuks, Z., & Kolesnick, R. (1995) · Cell · doi:10.1016/0092-8674(95)90429-8 · Cited by 826
Sphingolipids—The Enigmatic Lipid Class: Biochemistry, Physiology, and Pathophysiology
Merrill, A. H., Schmelz, E.-M., Dillehay, D. L., Spiegel, S., Shayman, J. A., Schroeder, J. J., Riley, R. T., Voss, K. A., & Wang, E. (1997) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1996.8029 · Cited by 643
Structure elucidation of the fumonisins, mycotoxins from Fusarium moniliforme
Bezuidenhout, S. C., Gelderblom, W. C. A., Gorst‐Allman, C. P., Horak, R. M., Marasas, W. F. O., Spiteller, G., & Vleggaar, R. (1988) · Journal of the Chemical Society Chemical Communications · doi:10.1039/c39880000743 · Cited by 617
Marasas, W. F. O., Riley, R. T., Hendricks, K. A., Stevens, V. L., Sadler, T. W., Gelineau-van Waes, J., Missmer, S. A., Cabrera, J., Torres, O., Gelderblom, W. C. A., et al. (2004) · The Journal of Nutrition · doi:10.1093/jn/134.4.711 · Cited by 604
Discovery and Occurrence of the Fumonisins: A Historical Perspective
Marasas, W. F. O. (2001) · Environmental Health Perspectives · doi:10.1289/ehp.01109s2239 · Cited by 567
Neural tube defects and folate: case far from closed
Blom, H. J., Shaw, G. M., den Heijer, M., & Finnell, R. H. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1986 · Cited by 562
Chu, F. S., & Li, G. Y. (1994) · Applied and Environmental Microbiology · doi:10.1128/aem.60.3.847-852.1994 · Cited by 529
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Tiwari, B. K., Brennan, C. S., Curran, T., Gallagher, E., Cullen, P. J., & O' Donnell, C. P. (2010) · Journal of Cereal Science · doi:10.1016/j.jcs.2010.01.007 · Cited by 288
Dietary mycotoxins, co-exposure, and carcinogenesis in humans: Short review
De Ruyck, K., De Boevre, M., Huybrechts, I., & De Saeger, S. (2015) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2015.07.003 · Cited by 268
Kumi, J., Mitchell, N., Asare, G., Dotse, E., Kwaa, F., Phillips, T., & Ankrah, N.-A. (2014) · Ghana Medical Journal · doi:10.4314/gmj.v48i3.1 · Cited by 59
Juan-García, A., Caprioli, G., Sagratini, G., Mañes, J., & Juan, C. (2021) · Toxins · doi:10.3390/toxins13020132 · Cited by 28
Metadata
- Authors
- Stockmann-Juvala, H., & Savolainen, K.
- Venue
- Human & Experimental Toxicology
- Publisher
- SAGE Publications
- Published
- 2008-11
- Volume
- 27
- Issue
- 11
- Pages
- 799-809
- ISSN
- 0960-3271 (ISSN-L)
- 1477-0903
- OpenAlex
- W2044120837
- Cited by
- 318
- References
- 45
- FWCI
- 11.95
- Type
- journal article
- Language
- en
- Open access
- closed
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