The Canadian Network for Mood and Anxiety Treatments (Canmat) Task Force Recommendations for the Management of Patients with Mood Disorders and Comorbid Conditions
Abstract
Background Medical comorbidity in patients with mood disorders has become an increasingly important clinical and global public health issue. Several specific medical conditions are associated with an increased risk of mood disorders, and conversely, mood disorders are associated with increased morbidity and mortality in patients with specific medical disorders. Methods To help understand the bidirectional relationship and to provide an evidence-based framework to guide the treatment of mood disorders that are comorbid with medical illness, we have reviewed relevant articles and reviews published in English-language databases (to April 2011) on the links between mood disorders and several common medical conditions, evaluating the efficacy and safety of pharmacologic and psychosocial treatments. The medical disorders most commonly encountered in adult populations (ie, cardiovascular disease, cerebrovascular disease, cancer, human immunodeficiency virus, hepatitis C virus, migraine, multiple sclerosis, epilepsy, and osteoporosis) were chosen as the focus of this review. Results Emerging evidence suggests that depression comorbid with several medical disorders is treatable and failure to treat depression in medically ill patients may have a negative effect on medical outcomes. Conclusions This review summarizes the available evidence and provides treatment recommendations for the management of comorbid depression in medically ill patients.
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TRD populations have a higher rate of psychiatric and physical comorbidities as compared to non-TRD populations.
“It is well established that TRD populations have a higher rate of psychiatric and physical comorbidities as compared to non- TRD populations 143 .”
From Treatment‐resistant depression: definition, prevalence, detection, management, and investigational interventions (2023) · cites this paper as [143]
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- Authors
- McIntyre, R. S., Schaffer, A., & Beaulieu, S.
- Affiliations
- University Health Network (CA)
- Sunnybrook Health Science Centre (CA)
- Douglas Mental Health University Institute (CA)
- Corresponding author
- McIntyre, Roger S.
- Venue
- Annals of Clinical Psychiatry
- Publisher
- SAGE Publications
- Published
- 2012-02
- Volume
- 24
- Issue
- 1
- Pages
- 2-3
- ISSN
- 1040-1237 (ISSN-L)
- 1547-3325
- OpenAlex
- W7214168743
- Cited by
- 11
- References
- 0
- Citations by year
- 2023: 1 · 2022: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 2
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Clinical Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed
- Topics
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Keywords
- mood disorders, anxiety disorders, comorbidities, treatment guidelines, depression, bipolar disorder
- MeSH terms
- Canada, Humans, Comorbidity, Practice Guidelines as Topic, Mood Disorders, Advisory Committees
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