The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The Relation Between Atherosclerosis and the Neutrophil–Lymphocyte Ratio
Abstract
Inflammation plays an important role in the pathophysiology of vascular disease. In this review, we consider the associations between the neutrophil–lymphocyte ratio (NLR; an indicator of inflammation) and vascular disease and its associated risk factors. The NLR has received attention due to its role as an independent prognostic factor for coronary artery disease. The NLR can also be affected by atherosclerotic risk factors, such as hypercholesterolemia, metabolic syndrome, diabetes, and hypertension. Importantly, it can predict mortality in cardiovascular diseases. There are also reports of a positive correlation between the NLR and commonly used inflammatory markers. Inflammation is important not only in pathophysiology but also clinical outcomes of many diseases. The NLR is a widely available, easily derived, and reproducible marker of inflammation. Unlike many other inflammatory markers, the NLR is inexpensive and readily available and it provides additional risk stratification beyond conventional risk scores.
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Cites
Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting
Gibson, P. H., Croal, B. L., Cuthbertson, B. H., Small, G. R., Ifezulike, A. I., Gibson, G., Jeffrey, R. R., Buchan, K. G., El-Shafei, H., & Hillis, G. S. (2007) · American Heart Journal · doi:10.1016/j.ahj.2007.06.043 · Cited by 382
Neutrophil to lymphocyte ratio may be predict of mortality in all conditions
Balta, S., Demirkol, S., Unlu, M., Arslan, Z., & Celik, T. (2013) · British Journal of Cancer · doi:10.1038/bjc.2013.598 · Cited by 124
Self-citation
Cited by
Metabolic syndrome is an inflammatory disorder: A conspiracy between adipose tissue and phagocytes
Reddy, P., Lent-Schochet, D., Ramakrishnan, N., McLaughlin, M., & Jialal, I. (2019) · Clinica Chimica Acta · doi:10.1016/j.cca.2019.06.019 · Cited by 297
Novel Systemic Inflammation Markers to Predict COVID-19 Prognosis
Karimi, A., Shobeiri, P., Kulasinghe, A., & Rezaei, N. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.741061 · Cited by 171
Erdoğan, M., Erdöl, M. A., Öztürk, S., & Durmaz, T. (2020) · Biomarkers in Medicine · doi:10.2217/bmm-2020-0274 · Cited by 128
Su, M., Ouyang, X., & Song, Y. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.04.038 · Cited by 80
Metadata
- Authors
- Balta, S., Celik, T., Mikhailidis, D. P., Ozturk, C., Demirkol, S., Aparci, M., & Iyisoy, A.
- Venue
- Clinical and Applied Thrombosis/Hemostasis
- Publisher
- SAGE Publications
- Published
- 2015-02-09
- Volume
- 22
- Issue
- 5
- Pages
- 405-411
- ISSN
- 1076-0296 (ISSN-L)
- 1938-2723
- OpenAlex
- W2069938556
- Cited by
- 404
- References
- 2
- FWCI
- 11.05
- Type
- journal article
- Language
- en
- Open access
- closed
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