The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
The Role of Vitamins and Minerals on the Immune System
Abstract
It has long been recognized that individuals living in poverty who suffer from malnutrition are more susceptible to infections and certain diseases due to deficiencies in macronutrients such as proteins, lipids, and carbohydrates. More recently, it has come to light that micronutrients such as several vitamins and minerals also play major roles in boosting the immune system to protect against certain infections, inflammation, and possibly some cancers. This article discusses the various immune boosting properties of several micronutrients.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Immune function may be improved by restoring deficient micronutrients to recommended levels, thereby increasing resistance to infection and supporting faster recovery when infected.”
From Immune function and micronutrient requirements change over the life course (2018) · cites this paper as [4]
In the citing paper
“Various micronutrients are essential for immunocompetence, particularly vitamins A, C, D, E, B2, B6, and B12, folic acid, iron, selenium, and zinc.”
From Immune function and micronutrient requirements change over the life course (2018) · cites this paper as [4]
In the citing paper
“poor nutritional status predisposes to certain infections.”
From Immune function and micronutrient requirements change over the life course (2018) · cites this paper as [4]
In the citing paper
“As outlined in Table 1, micronutrients have essential roles in the immune system and an inadequate intake may have deleterious effects [4].”
From Immune function and micronutrient requirements change over the life course (2018) · cites this paper as [4]
In the citing paper
“Micronutrient deficiencies also have immunological consequences in infants and young children, and can increase morbidity and mortality from many diseases, including pneumonia, diarrheal disease, and measles [4,49].”
From Immune function and micronutrient requirements change over the life course (2018) · cites this paper as [4]
In the citing paper
“Immune defenses can be impaired by undernutrition, which increases susceptibility to infection [4,5,70].”
From Immune function and micronutrient requirements change over the life course (2018) · cites this paper as [4]
In the citing paper
“The development, maintenance and optional functioning of immune cells is dependent on adequate nutrition, evident at all stages of life [4,5,33,49,69].”
From Immune function and micronutrient requirements change over the life course (2018) · cites this paper as [4]
Citations
Cites
Carr, A. C., & Frei, B. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.6.1086 · Cited by 940
Vitamin D: its role and uses in immunology 1
DeLuca, H. F., & Cantorna, M. T. (2001) · The FASEB Journal · doi:10.1096/fj.01-0433rev · Cited by 784
Contribution of Selected Vitamins and Trace Elements to Immune Function
Wintergerst, E. S., Maggini, S., & Hornig, D. H. (2007) · Annals of Nutrition and Metabolism · doi:10.1159/000107673 · Cited by 692
Percival, S. (1998) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/67.5.1064s · Cited by 370
Nutrition and the immune system from birth to old age
Chandra, R. (2002) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601492 · Cited by 369
The immune system: a target for functional foods?
Calder, P. C., & Kew, S. (2002) · British Journal Of Nutrition · doi:10.1079/bjn2002682 · Cited by 359
Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation
Bruno, R. S., Leonard, S. W., Atkinson, J., Montine, T. J., Ramakrishnan, R., Bray, T. Μ., & Traber, M. G. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.10.051 · Cited by 185
Vitamin A as “Anti-Infective” Therapy, 1920–1940
Semba, R. D. (1999) · Journal of Nutrition · doi:10.1093/jn/129.4.783 · Cited by 143
Effect of antioxidative vitamins on immune function with clinical applications.
Grimble, R. F. (1997) · PubMed · Cited by 109
Research works printed but not linked: 1
- Grimble RF., 1997, Int J Vitam Nutr Res, 67, 312
Cited by
Sorted by citations
A Review of Micronutrients and the Immune System–Working in Harmony to Reduce the Risk of Infection
Gombart, A. F., Pierre, A., & Maggini, S. (2020) · Nutrients · doi:10.3390/nu12010236 · Cited by 1,358
Iddir, M., Alex Brito, O., Dingeo, G., Sosa, S., Samouda, H., Frano, M. R. L., & Bohn, T. (2020) · Nutrients · doi:10.3390/nu12061562 · Cited by 825
Immune function and micronutrient requirements change over the life course
Maggini, S., Pierre, A., & Calder, P. C. (2018) · Nutrients · doi:10.3390/nu10101531 · Cited by 710
“The development, maintenance and optional functioning of immune cells is dependent on adequate nutrition, evident at all stages of life [4,5,33,49,69].”
BackgroundInfluentialNutrition, immunity and COVID-19
Calder, P. C. (2020) · BMJ Nutrition Prevention & Health · doi:10.1136/bmjnph-2020-000085 · Cited by 612
Neuroinflammation in Alzheimer’s Disease
Onyango, I. G., Jauregui, G. V., Čarná, M., Bennett, J. P., & Stokin, G. B. (2021) · Biomedicines · doi:10.3390/biomedicines9050524 · Cited by 330
Metadata
- Authors
- Alpert, P. T.
- Affiliations
- Arizona College, Las Vegas Campus, NV, USA
- Corresponding author
- Alpert, Patricia T.
- Venue
- Home Health Care Management & Practice
- Publisher
- SAGE Publications
- Published
- 2017-06-06
- Volume
- 29
- Issue
- 3
- Pages
- 199-202
- ISSN
- 1084-8223 (ISSN-L)
- 1552-6739
- OpenAlex
- W2621887820
- Semantic Scholar
- a48e42c800ffa8225354da805a2248bd37246a19
- Cited by
- 120
- References
- 9
- Citations by year
- 2026: 1 · 2025: 12 · 2024: 16 · 2023: 16 · 2022: 16 · 2021: 29 · 2020: 26 · 2019: 3 · 2018: 1
- FWCI
- 8.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Home Health Care Management & Practice (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
- Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
- Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
- Keywords
- vitamins, minerals, micronutrients, immune system, malnutrition, infection susceptibility, inflammation, cancer prevention, poverty
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review