Cited by 169Peripheral Artery Disease ManagementAtherosclerosis and Cardiovascular DiseasesVascular Procedures and Complications

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Peripheral artery disease and risk of cardiovascular events in patients with coronary artery disease: Insights from the Heart and Soul Study

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Grenon, S Marlene, Vittinghoff, Eric, Owens, Christopher D, Conte, Michael S, Whooley, Mary, Cohen, Beth E·2013·Vascular Medicine

DOI 10.1177/1358863x13493825PMC PMC4207208

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Abstract

Among patients with coronary artery disease (CAD), those with peripheral artery disease (PAD) have a greater vulnerability to cardiovascular (CV) events than those with CAD alone. In a prospective cohort study of patients with CAD, we evaluated potential mechanisms that might explain the adverse CV outcomes associated with PAD. We performed a prospective cohort study of 1018 patients with stable CAD who were recruited from 2000 to 2002. Incident symptomatic PAD events were adjudicated during a follow-up period of 7.2 ± 2.6 years. We used Cox proportional hazards models to evaluate the association between incident symptomatic PAD events and subsequent risk of CV events or death. Models were adjusted for demographics, traditional risk factors, inflammation, insulin resistance and health behaviors. Among the 1018 patients, 50 patients who did not report a history of PAD at baseline suffered incident symptomatic PAD events during the follow-up period. Those patients had a higher risk of subsequent CV events and death compared to those who did not develop PAD. After adjustment for traditional risk factors, symptomatic PAD events remained associated with a 70% increased risk of subsequent CV events (adjusted HR 1.7; 95% CI 1.0, 2.9; p = 0.04) and an 80% increased risk of death (adjusted HR 1.8; 95% CI 1.2, 2.7; p = 0.006). Inflammatory biomarkers were the strongest risk factor contributing to the excess risk. In a contemporary cohort of patients with CAD, incident symptomatic PAD events were associated with an increased risk for subsequent CV events. The increased vulnerability to CV events was partially explained by shared CV risk factors and inflammation.

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Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man
Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502
Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines
Grundy, S. M., Cleeman, J. I., Merz, C. N. B., Brewer, H. B., Clark, L. T., Hunninghake, D. B., Pasternak, R. C., Smith, S. C., & Stone, N. J. (2004) · Circulation · doi:10.1161/01.cir.0000133317.49796.0e · Cited by 6,902
Universal Definition of Myocardial Infarction
Thygesen, K. A., Alpert, J. S., White, H. D., TASK FORCE MEMBERS: Chairpersons: Kristian Thygesen (Denmark), J. S. A. (., Biomarker Group: Allan S. Jaffe, C. (., ECG Group: Bernard Chaitman, C.-O. (., Imaging Group: Richard Underwood, C. (., Intervention Group: Jean-Pierre Bassand, C.-O. (., Mendis, S., Implementation Group: Lars C. Wallentin Coordinator (Sweden), F. F.-A. (., et al. (2007) · Circulation · doi:10.1161/circulationaha.107.187397 · Cited by 4,422
ACC/AHA 2005 Practice Guidelines for the Management of Patients With Peripheral Arterial Disease (Lower Extremity, Renal, Mesenteric, and Abdominal Aortic): A Collaborative Report from the American Association for Vascular Surgery/Society for Vascular Surgery,* Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease): Endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation
Hirsch, A. T., Haskal, Z. J., Hertzer, N. R., Bakal, C. W., Creager, M. A., Halperin, J. L., Hiratzka, L. F., Murphy, W. R. C., Olin, J. W., Puschett, J. B., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.174526 · Cited by 3,708
Mortality over a Period of 10 Years in Patients with Peripheral Arterial Disease
Criqui, M. H., Langer, R. D., Fronek, A., Feigelson, H. S., Klauber, M. R., McCann, T. J., & Browner, D. (1992) · New England Journal of Medicine · doi:10.1056/nejm199202063260605 · Cited by 2,579
Novel Risk Factors for Systemic Atherosclerosis
Ridker, P. M., Stampfer, M. J., & Rifai, N. (2001) · JAMA · doi:10.1001/jama.285.19.2481 · Cited by 1,290
ACC/AHA 2005 Guidelines for the Management of Patients With Peripheral Arterial Disease (Lower Extremity, Renal, Mesenteric, and Abdominal Aortic): Executive Summary A Collaborative Report From the American Association for Vascular Surgery/Society for Vascular Surgery,⁎⁎AAVS/SVS when Guideline initiated, now merged into SVSSociety for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease)
Hirsch, A. T., Haskal, Z. J., HERTZER, N. R., Bakal, C. W., Creager, M. A., Halperin, J. L., Hiratzka, L. F., Murphy, W. R. C., Olin, J. W., Puschett, J. B., et al. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.10.009 · Cited by 1,029
Plasma Concentration of C-Reactive Protein and Risk of Developing Peripheral Vascular Disease
Ridker, P. M., Cushman, M., Stampfer, M. J., Tracy, R. P., & Hennekens, C. H. (1998) · Circulation · doi:10.1161/01.cir.97.5.425 · Cited by 973
Relationship of High and Low Ankle Brachial Index to All-Cause and Cardiovascular Disease Mortality
Resnick, H. E., Lindsay, R. S., McDermott, M. M., Devereux, R. B., Jones, K. L., Fabsitz, R. R., & Howard, B. V. (2004) · Circulation · doi:10.1161/01.cir.0000112642.63927.54 · Cited by 925
Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease
Whooley, M. A. (2008) · JAMA · doi:10.1001/jama.2008.711 · Cited by 887
Self-citation
Ankle-Arm Index as a Predictor of Cardiovascular Disease and Mortality in the Cardiovascular Health Study
Newman, A. B., Shemanski, L., Manolio, T. A., Cushman, M., Mittelmark, M., Polak, J. F., Powe, N. R., & Siscovick, D. (1999) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.19.3.538 · Cited by 871
Case Definitions for Acute Coronary Heart Disease in Epidemiology and Clinical Research Studies
Luepker, R. V., Apple, F. S., Christenson, R. H., Crow, R. S., Fortmann, S. P., Goff, D. C., Goldberg, R. J., Hand, M. M., Jaffe, A. S., Julian, D. G., et al. (2003) · Circulation · doi:10.1161/01.cir.0000100560.46946.ea · Cited by 810
Incidence, Natural History and Cardiovascular Events in Symptomatic and Asymptomatic Peripheral Arterial Disease in the General Population
Leng, G. C., Lee, A. J., FOWKERS, F. G. R., Whiteman, M., Dunbar, J., Housley, E., & Ruckley, C. V. (1996) · International Journal of Epidemiology · doi:10.1093/ije/25.6.1172 · Cited by 663
Stroke Incidence, Case Fatality, and Mortality in the WHO MONICA Project
Thorvaldsen, P., Asplund, K., Kuulasmaa, K., Rajakangas, A.-M., & Schroll, M. (1995) · Stroke · doi:10.1161/01.str.26.3.361 · Cited by 536
Use of ankle brachial pressure index to predict cardiovascular events and death: a cohort study
Leng, G. C., Fowkes, F. G. R., Alexander, L. E. E., Dunbar, J., Housley, E., & Ruckley, C. V. (1996) · BMJ · doi:10.1136/bmj.313.7070.1440 · Cited by 525
Peripheral Arterial Disease: Morbidity and Mortality Implications
Golomb, B. A., Dang, T. T., & Criqui, M. H. (2006) · Circulation · doi:10.1161/circulationaha.105.593442 · Cited by 498
C-Reactive Protein, Interleukin-6, and Soluble Adhesion Molecules as Predictors of Progressive Peripheral Atherosclerosis in the General Population
Tzoulaki, I., Murray, G. D., Lee, A. J., Rumley, A., Lowe, G. D. O., & Fowkes, F. G. R. (2005) · Circulation · doi:10.1161/circulationaha.104.513085 · Cited by 432
Reliability and validity of self-reported physical activity in the Nord-Trøndelag Health Study — HUNT 1
Kurtze, N., Rangul, V., Hustvedt, B., & Flanders, W. D. (2008) · Scandinavian Journal of Public Health · doi:10.1177/1403494807085373 · Cited by 345
Validity and reliability of self-reported physical activity status: the Lipid Research Clinics questionnaire
Ainsworth, B. E., Jacobs, D. R., & Leon, A. S. (1993) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-199301000-00013 · Cited by 345
Self-reported Medication Adherence and Cardiovascular Events in Patients With Stable Coronary Heart Disease The Heart and Soul Study
Gehi, A. K. (2007) · Archives of Internal Medicine · doi:10.1001/archinte.167.16.1798 · Cited by 339
Morbidity and mortality in hypertensive adults with a low ankle/arm blood pressure index
Newman, A. B. (1993) · JAMA · doi:10.1001/jama.270.4.487 · Cited by 300
Fate in intermittent claudication: outcome and risk factors.
Jelnes, R., Gaardsting, O., Jensen, K., Bækgaard, N., Tønnesen, K. H., & Schroeder, T. V. (1986) · BMJ · doi:10.1136/bmj.293.6555.1137 · Cited by 298
Morbidity and Mortality in Hypertensive Adults With a Low Ankle/Arm Blood Pressure Index
Newman, A. B. (1993) · JAMA · doi:10.1001/jama.1993.03510040091035 · Cited by 257
Long-Term Prognosis of Patients With Peripheral Arterial Disease
Welten, G. M. J. M., Schouten, O., Hoeks, S. E., Chonchol, M., Vidaković, R., van Domburg, R. T., Bax, J. J., van Sambeek, M. R. H. M., & Poldermans, D. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.11.077 · Cited by 230
Long-term survival in patients with coronary artery disease: Importance of peripheral vascular disease
Eagle, K. A., Rihal, C. S., Foster, E. D., Mickel, M. C., & Gersh, B. J. (1994) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(94)90596-7 · Cited by 216
Depression and inflammation in patients with coronary heart disease: findings from the Heart and Soul Study
Whooley, M. A., Caska, C. M., Hendrickson, B. E., Rourke, M. A., Ho, J., & Ali, S. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.10.016 · Cited by 171
Self-citation
Multinational Comparisons of Stroke Epidemiology
Asplund, K., Bonita, R., Kuulasmaa, K., Rajakangas, A.-M., Feigin, V. L., Schaedlich, H., Suzuki, K., Thorvaldsen, P., & Tuomilehto, J. (1995) · Stroke · doi:10.1161/01.str.26.3.355 · Cited by 153
Prior peripheral arterial disease and cerebrovascular disease are independent predictors of adverse outcome in patients with acute coronary syndromes: Are we doing enough? Results from the Orbofiban in Patients with Unstable Coronary Syndromes-Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study
Cotter, G., Cannon, C. P., McCabe, C. H., Michowitz, Y., Kaluski, E., Charlesworth, A., Milo, O., Bentley, J., Blatt, A., Krakover, R., et al. (2003) · American Heart Journal · doi:10.1067/mhj.2003.6 · Cited by 150
The Prevalence of Peripheral Arterial Disease in High Risk Subjects and Coronary or Cerebrovascular Patients
Poredoš, P., & Jug, B. (2007) · Angiology · doi:10.1177/0003319707302494 · Cited by 139
Self-reported physical activity compared with maximal oxygen uptake in adults
Aadahl, M., Kjær, M., Kristensen, J. H., Mollerup, B., & Jørgensen, T. (2007) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e3280128d00 · Cited by 136
The AUDIT-C: screening for alcohol use disorders and risk drinking in the presence of other psychiatric disorders
Dawson, D. A., Grant, B. F., & Stinson, F. S. (2005) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2005.01.006 · Cited by 135
Peripheral Arterial Disease and Progression of Coronary Atherosclerosis
Hussein, A. A., Uno, K., Wolski, K., Kapadia, S., Schoenhagen, P., Tuzcu, E. M., Nissen, S. E., & Nicholls, S. J. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.10.034 · Cited by 108
The effect of intensified lipid-lowering therapy on long-term prognosis in patients with peripheral arterial disease
Feringa, H. H. H., Karagiannis, S. E., van Waning, V. H., Boersma, E. H., Schouten, O., Bax, J. J., & Poldermans, D. (2007) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2007.01.024 · Cited by 106
Comparison of Usefulness of Inflammatory Markers in Patients With Versus Without Peripheral Arterial Disease in Predicting Adverse Cardiovascular Outcomes (Myocardial Infarction, Stroke, and Death)
Beckman, J. A., Preis, O., Ridker, P. M., & Gerhard‐Herman, M. D. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2005.07.041 · Cited by 104
Construct Validity of Self-reported Historical Physical Activity
Bowles, H. R. (2004) · American Journal of Epidemiology · doi:10.1093/aje/kwh209 · Cited by 100
Lower extremity peripheral arterial disease in hospitalized patients with coronary artery disease
Dieter, R. S., Tomasson, J., Gudjonsson, T., Brown, R., Vitcenda, M., Einerson, J. A., & McBride, P. E. (2003) · Vascular Medicine · doi:10.1191/1358863x03vm506ra · Cited by 97
Prevalence and Prognosis of Asymptomatic Left Ventricular Diastolic Dysfunction in Ambulatory Patients With Coronary Heart Disease
Ren, X., Ristow, B., Na, B., Ali, S., Schiller, N. B., & Whooley, M. A. (2007) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2007.01.041 · Cited by 91
Self-citation
Construct Validity Evidence for Single-Response Items to Estimate Physical Activity Levels in Large Sample Studies
Jackson, A. W., Morrow, J. R., Bowles, H. R., FitzGerald, S. J., & Blair, S. N. (2007) · Research Quarterly for Exercise and Sport · doi:10.1080/02701367.2007.10599400 · Cited by 75
Peripheral artery disease in patients with coronary artery disease.
Atmer, B., Jogestrand, T., Laska, J., & Lund, F. (1995) · PubMed · Cited by 41
Coronary, Peripheral and Cerebrovascular Disease: a Complex Relationship
Shah, A. M., Banerjee, T., & Mukherjee, D. (2008) · Herz · doi:10.1007/s00059-008-3152-y · Cited by 27
Association between Omega–3 Fatty Acids and Depressive Symptoms among Patients with Established Coronary Artery Disease: Data from the Heart and Soul Study
Ali, S., Garg, S. K., Cohen, B. E., Bhave, P. D., Harris, W. S., & Whooley, M. A. (2009) · Psychotherapy and Psychosomatics · doi:10.1159/000203118 · Cited by 24
Self-citation
Koronare, periphere und zerebrovaskuläre Krankheit: ein komplexes Beziehungsmuster
Shah, A. M., Banerjee, T., & Mukherjee, D. (2008) · Herz · Cited by 15
Endotheliale Dysfunktion und kardiovaskuläre Ereignisse bei Patienten mit peripherer arterieller Verschlusskrankheit
Pasqualini, Marchesi, Vaudo, Siepi, Angeli, F., Paris, Schillaci, & Mannarino (2003) · VASA · doi:10.1024/0301-1526.32.3.139 · Cited by 14

Research works printed but not linked: 1

Atmer B, 1995, Int Angiol, 14, 89

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Authors: Grenon, S. M., Vittinghoff, E., Owens, C. D., Conte, M. S., Whooley, M., & Cohen, B. E.
Affiliations: San Francisco VA Medical Center (US)
University of California, San Francisco (US)
ORCID: Grenon, S Marlene
Vittinghoff, Eric
Owens, Christopher D
Conte, Michael S
Whooley, Mary
Cohen, Beth E
Venue: Vascular Medicine
Publisher: SAGE Publications
Published: 2013-07-08
Volume: 18
Issue: 4
Pages: 176-184
ISSN: 1358-863X (ISSN-L)
1477-0377
DOI: 10.1177/1358863x13493825
PMC: PMC4207208
OpenAlex: W2143326022
Semantic Scholar: 08d4713059ce5163268ed15c032dddebff564a7b
Cited by: 169
References: 43
Citations by year: 2026: 8 · 2025: 21 · 2024: 15 · 2023: 17 · 2022: 18 · 2021: 21 · 2020: 9 · 2019: 14 · 2018: 18 · 2017: 8 · 2016: 8 · 2015: 5 · 2014: 6 · 2013: 1
FWCI: 6.57
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: Vascular Medicine (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
eScholarship (California Digital Library) (submittedVersion)
Funders: National Heart, Lung, and Blood Institute (K23HL094765, R01HL079235)
National Center for Research Resources (KL2RR024130)
Topics: Health Sciences › Medicine › Surgery › Peripheral Artery Disease Management
Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Vascular Procedures and Complications
Keywords: peripheral arterial disease, coronary artery disease, cardiovascular events, cardiovascular mortality, inflammation, inflammatory markers, Heart and Soul Study
MeSH terms: Aged, Coronary Artery Disease, Female, Humans, Male, Middle Aged, Prognosis, Prospective Studies, Risk Factors, San Francisco, Time Factors, Biomarkers, Incidence, Multivariate Analysis, Proportional Hazards Models, Disease Progression, Inflammation Mediators, Peripheral Arterial Disease

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Peripheral artery disease and risk of cardiovascular events in patients with coronary artery disease: Insights from the Heart and Soul Study

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